Rechargeable Batteries Including High-Voltage Cathode and Redox Shuttle Conferring Overcharge Protection

Compounds for use as photoredox catalysts and as redox shuttles in a rechargeable battery having a high-voltage cathode providing overcharge protection capabilities are provided, including a compound according to the formula: (see patent for formula) wherein R is selected from the group consisting of alkyl, aryl, alkylaryl, alkoxyaryl, alkylcarboxyl, aryl carbonyl, haloalkyl, perfluoroalkyl, glycols, haloaryl, a negative electrolyte, and a polymer

Spacetime Singularities in String and its Low Dimensional Effective Theory

Spacetime singularities are studied in both the $D+d$-dimensional string theory and its $D$-dimensional effective theory, obtained by the Kaluza-Klein compactification. It is found that spacetime singularities in the low dimensional effective theory may or may not remain after lifted to the $D+d$-dimensional string theory, depending on particular solutions. It is also found that there exist cases in which spacetime singularities appearing in high/low dimensional spacetimes do not necessarily happen on the same surfaces.Comment: revtex4, 15 pages, 10 figures. Typos are corrected. Version to appear in Inter. J. Mod. Phys.

Liquid Phenothiazine Catholytes for Non-Aqueous Redox Flow Batteries

Highly soluble, liquid phenothiazines containing methoxy-terminated ether and oligoether substituents are disclosed with high diffusion coefficients and robust performance in electrochemical measurements, which can be synthesized in one step from commercially-available starting materials, thereby circumventing previous synthetic limitations

CRC-derived exosomes containing the RNA binding protein HuR promote lung cell proliferation by stabilizing c-Myc mRNA

HuR overexpression is related to poor survival in patients with colon cancer. HuR overexpression leads to stabilization of tumor-promoting mRNAs by binding to 3′UTR-resident AREs. Exosomes, nanosized lipid bilayer vesicles, mediate many steps in cancer progression. The potential role of exosomal HuR in colon cancer lung metastasis is unclear. HuR expression was assessed immunohistochemically in tumor tissue samples from 20 patients with metastatic or nonmetastatic colon cancer and colon cancer lung metastasis and benign lung disease samples from ten patients. Exosomes were isolated from HCT116 WT and HuR KO colon cancer cells, and uptake of PKH67- and PKH26-labeled exosomes by BEAS-2B cells was evaluated using fluorescence and confocal microscopy. C-Myc and p21protein and mRNA levels were measured by western blotting and RT-qPCR, respectively. In clinical patients, HuR overexpression was significantly enhanced in colon tissues of patients with lung metastasis. HuR expression was higher in lung tissue with metastasis of colonic origin than with benign lung disease. The effect of HuR-containing CRC exosomes compared to HuR-deficient exosomes on wound closure was observed as enhanced proliferation. BEAS-2B cell migration and invasion were enhanced after HuR-containing exosomes treatment. BEAS-2B cells showed similar uptake of PKH67 (HCT116 WT)- and PKH26 (HCT116 HuR KO)-labeled exosomes. Exosomal HuR stabilized c-Myc mRNA and downregulated p21 expression, leading to G1/S transition, in human bronchial epithelial cells. HuR overexpression is associated with lung metastasis in colon cancer patients. Exosomal HuR derived from colon cancer cells alter the biological effect on normal lung epithelial cells

Immune checkpoints and immunotherapy for colorectal cancer

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Two-Electron Donating Phenothiazines and Use Thereof

Compounds for use as electrolyte in a non-aqueous redox battery are provided, including an N-substituted phenothiazine compound according to the formula: (see patent for formula.) R\u27 is alkyl and R is selected from alkyl, aryl, alkylaryl, alkoxyaryl, alkylcarboxyl, arylcarbonyl, haloalkyl, perfluo- roalkyl, glycol, polyether, haloaryl, a negative electrolyte, a polymerizable unit, and a polymer

Non-Aqueous Redox Flow Batteries Including 3,7-Perfluoroalkylated Phenothiazine Derivatives

A non-aqueous redox flow battery includes a negative electrode immersed in a first non-aqueous liquid electrolyte solution, a positive electrode immersed in a second nonaqueous liquid electrolyte solution, and a semi-permeable separator interposed between the negative and positive electrodes, wherein the second the non-aqueous liquid electrolyte solution comprises a compound of the formula... To see the remainder of this abstract, please download this patent

Impact of seam on liquid transmission behaviour of multi-layered ensembles using sweat and water

Present study is focussed on the effect of seam on the moisture transmission in liquid form. Behaviour of actual sweat is found to be different from pure water used while evaluating the performance of multilayer clothing systems in seamed and unseamed condition in terms of their in-plane (wetting time) & cross-plane moisture transmission and overall moisture management capacity. Uni-directional seam shows higher wetting time at the inner surface as well as better cross-plane transmittance, and hence better overall moisture management capacity as compared to bi-directional stitched and unseamed fabrics. In all the cases, sweat shows less wetting time than water. Multi-layered ensemble with polyester spacer fabric as middle layer exhibits better overall moisture management properties in comparison to layered ensemble with fleece fabric as middle layer both in seamed and unseamed conditions. Seam type plays a most significant role followed by type of layered ensembles then solution type in affecting the overall moisture management behaviour of seamed ensembles

Impact of varying lactate concentration in sweat on liquid moisture transmission behaviour of layered ensembles

The present study is focussed on the impact of change in the lactate concentration (43 mM and 22 mM) in sweat solution on liquid moisture transmission behaviour through the clothing. The sweat solution with higher concentration of lactate (43 mM) shows delayed wetting at the top surface both in case of individual layer and multi-layer fabric ensembles, i.e. it takes longer time to wet the top surface in spite of the lower contact angle made by it. Significant difference is observed in in-plane transmission behaviour of both the sweat solutions in the case of multi-layered ensembles. In case of multi-layered ensembles, wetting time reduces drastically, even though both the ensembles consist of polyester knit as the inner surface possessing wetting time is 50 s approximately. Sweat solution with higher lactate concentration also shows higher cross-planar transmission rate as compared to in-plane transmission. Uni-directional seamed multi-layered spacer fabric exhibits better overall moisture management coefficient as compared to bi-directional seamed spacer ensembles with sweat solution containing higher lactate concentration. Middle layer also plays a vital role in altering the overall liquid moisture transmission behaviour