3,177 research outputs found
Features of ion acceleration by circularly polarized laser pulses
The characteristics of a MeV ion source driven by superintense, ultrashort
laser pulses with circular polarization are studied by means of
particle-in-cell simulations. Predicted features include high efficiency, large
ion density, low divergence and the possibility of femtosecond duration. A
comparison with the case of linearly polarized pulses is made.Comment: 4 pages, 4 figure
"Single-cycle" ionization effects in laser-matter interaction
We investigate numerically effects related to ``single-cycle'' ionization of
dense matter by an ultra-short laser pulse. The strongly non-adiabatic response
of electrons leads to generation of a megagauss steady magnetic field in
laser-solid interaction. By using two-beam interference, it is possible to
create periodic density structures able to trap light and to generate
relativistic ionization frontsComment: 12 pages, 6 figures, to be published in Laser and Particle Beam
Solitary versus Shock Wave Acceleration in Laser-Plasma Interactions
The excitation of nonlinear electrostatic waves, such as shock and solitons,
by ultraintense laser interaction with overdense plasmas and related ion
acceleration are investigated by numerical simulations. Stability of solitons
and formation of shock waves is strongly dependent on the velocity distribution
of ions. Monoenergetic components in ion spectra are produced by "pulsed"
reflection from solitary waves. Possible relevance to recent experiments on
"shock acceleration" is discussed.Comment: 4 pages, 4 figure
Laser ion acceleration using a solid target coupled with a low density layer
We investigate by particle-in-cell simulations in two and three dimensions
the laser-plasma interaction and the proton acceleration in multilayer targets
where a low density "near-critical" layer of a few micron thickness is added on
the illuminated side of a thin, high density layer. This target design can be
obtained by depositing a "foam" layer on a thin metallic foil. The presence of
the near-critical plasma strongly increases both the conversion efficiency and
the energy of electrons and leads to enhanced acceleration of proton from a
rear side layer via the Target Normal Sheath Acceleration mechanism. The
electrons of the foam are strongly accelerated in the forward direction and
propagate on the rear side of the target building up a high electric field with
a relatively flat longitudinal profile. In these conditions the maximum proton
energy is up to three times higher than in the case of the bare solid target.Comment: 9 pages, 11 figures. Submitted to Physical Review
Programmed cell death and natural killer cells in multiple sclerosis: New potential therapeutic targets?
Two-surface wave decay: improved analytical theory and effects on electron acceleration
Two-surface wave decay (TSWD), i.e. the parametric excitation of electron
surface waves, was recently proposed as an absorption mechanism in the
interaction of ultrashort, intense laser pulses with solid targets. We present
an extension of the fluid theory of TSWD to a warm plasma which treats boundary
effects consistently. We also present test-particle simulations showing
localized enhancement of electron acceleration by TSWD fields; this effect
leads to a modulation of the current density entering into the target and may
seed current filamentation instabilities.Comment: 4 figures, submitted to Appl.Phys.B (special issue from HFSW X
conference, Biarritz, France, Oct 12-15 2003); slightly revised tex
Analyse chimique continue de la mer: II. Mission internationale <i>Mechelen</i> 1968 en Méditerranée
Results of automatic and continuous analysis of both physical and chemical parameters of sea water between Marbella (Malaga) and Brest (Mechelen cruise, Mediterranean 1968, supported by the « Institut royal des Sciences naturelles de Belgique ») are studied in this paper.Two conclusions are reached: 1° The distribution of salinity, temperature and nitrate, sometimes anomalous, appears to follow some rythm or law. 2° There appears a close spacial relationship too between these anomalies and fishery. Then, it is possible to use the continuous automatic method for the exploratory work on fishery technology
Particle acceleration and radiation friction effects in the filamentation instability of pair plasmas
The evolution of the filamentation instability produced by two
counter-streaming pair plasmas is studied with particle-in-cell (PIC)
simulations in both one (1D) and two (2D) spatial dimensions. Radiation
friction effects on particles are taken into account. After an exponential
growth of both the magnetic field and the current density, a nonlinear
quasi-stationary phase sets up characterized by filaments of opposite currents.
During the nonlinear stage, a strong broadening of the particle energy spectrum
occurs accompanied by the formation of a peak at twice their initial energy. A
simple theory of the peak formation is presented. The presence of radiative
losses does not change the dynamics of the instability but affects the
structure of the particle spectra.Comment: 8 pages, 8 figures, submitted to MNRA
Widening use of dexamethasone implant for the treatment of macular edema
Sustained-release intravitreal 0.7 mg dexamethasone (DEX) implant is approved in Europe for the treatment of macular edema related to diabetic retinopathy, branch retinal vein occlusion, central retinal vein occlusion, and non-infectious uveitis. The implant is formulated in a biodegradable copolymer to release the active ingredient within the vitreous chamber for up to 6 months after an intravitreal injection, allowing a prolonged interval of efficacy between injections with a good safety profile. Various other ocular pathologies with inflammatory etiopathogeneses associated with macular edema have been treated by DEX implant, including neovascular age-related macular degeneration, Irvine–Gass syndrome, vasoproliferative retinal tumors, retinal telangiectasia, Coats’ disease, radiation maculopathy, retinitis pigmentosa, and macular edema secondary to scleral buckling and pars plana vitrectomy. We undertook a review to provide a comprehensive collection of all of the diseases that benefit from the use of the sustained-release DEX implant, alone or in combination with concomitant therapies. A MEDLINE search revealed lack of randomized controlled trials related to these indications. Therefore we included and analyzed all available studies (retrospective and prospective, comparative and non-comparative, randomized and nonrandomized, single center and multicenter, and case report). There are reports in the literature of the use of DEX implant across a range of macular edema-related pathologies, with their clinical experience supporting the use of DEX implant on a case-by-case basis with the aim of improving patient outcomes in many macular pathologies. As many of the reported macular pathologies are difficult to treat, a new treatment option that has a beneficial influence on the clinical course of the disease may be useful in clinical practice
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