6 research outputs found

    Conceptual Framework for a Data Model to Support Asset Management Decision-Making Process

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    Part 4: Product and Asset Life Cycle Management in Smart Factories of Industry 4.0International audienceInformation and data management is nowadays a central issue to support the Asset Management (AM) decision-making process. Manufacturing companies have to take different decisions along the asset lifecycle and at different organisational levels, and, to this end, they require proper information and data management. In the literature, besides the crucial role played by information and data, there is evidence of existing gaps, especially related to information management and integration, and transformation of data into useful information. Thus, a conceptual framework is proposed to guide the definition of a data model to fulfil the previously identified gap. Generally, the framework aims at contributing to the improvement of the integration of information along the AM decision-making process. Specifically, it is intended to be aligned with the AM theory and, in particular, its fundamentals defined in the scientific literature and the ISO 5500x body of standards. Overall, thanks to the improvement of the information management and integration along with the AM decision-making, the expectation is to be capable of achieving more value-oriented decisions for the asset lifecycle

    Intestinal hormones, gut microbiota and non-alcoholic fatty liver disease

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    Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and has a complex pathophysiology with multiple pathways of development and progression implicated. Intestinal hormones regulate multiple biological functions and may play a role in the pathogenesis of non alcoholic fatty liver disease (NAFLD) by affecting food intake, body weight and insulin resistance. Bacterial products can affect the secretion of these hormones and thus have an effect on metabolism. Gut microbiota are normally involved in the intestinal energy harvest and their role has been increasingly been implicated in the pathogenesis of obesity and NAFLD. The intestinal hormone pathways as well as the intestinal microbiota populations are potential therapeutic targets in the management of NAFLD. We review the evidence on the associations of the intestinal hormones and gut microbiota in the development, progression and treatment of NAFLD

    Approach on Analysis of Heterogeneous Requirements in Software Engineering

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    Innovation projects in information and communication technology often include a lot of end users with different use cases that results in very heterogeneous requirements. This requires a special approach for analysis and categorization of the requirements as well as for converging to one architecture solution, which addresses the needs of all end users. The communication between end users and developers should be supported correspondingly. This is relevant in different research and software development projects that involve a lot of users and developers. This paper describes the approach on analysis of heterogeneous requirements that extends traditional approaches with additional iterative steps aiming to find the commonalities between use cases. The approach was validated in the large research EU funded project PLANTCockpi

    Adult and paediatric GERD: diagnosis, phenotypes and avoidance of excess treatments

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