10 research outputs found
Selective etching characteristics of the AgInSbTe phase-change film in laser thermal lithography
Size-exclusion chromatographic behavior of bovine serum albumin in uni-uni valent ions solutions
Testosterone levels in obese male patients with obstructive sleep apnea syndrome: Relation to oxygen desaturation, body weight, fat distribution and the metabolic parameters
Microcomputer assisted, single beam, photoacoustic spectrometer system for the study of solids
Liquid chromatographic separation of phosphorus oxo acids and other anions with post-column indirect fluorescence detection by aluminum-morin
Analysis of commercial sodium tripolyphosphates by phosphorus-31 Fourier transform nuclear magnetic resonance spectrometry
Genome Sequence and Analysis of a Propionibacterium acnes Bacteriophageâ–¿ â€
Cutaneous propionibacteria are important commensals of human skin and are implicated in a wide range of opportunistic infections. Propionibacterium acnes is also associated with inflammatory acne vulgaris. Bacteriophage PA6 is the first phage of P. acnes to be sequenced and demonstrates a high degree of similarity to many mycobacteriophages both morphologically and genetically. PA6 possesses an icosahedreal head and long noncontractile tail characteristic of the Siphoviridae. The overall genome organization of PA6 resembled that of the temperate mycobacteriophages, although the genome was much smaller, 29,739 bp (48 predicted genes), compared to, for example, 50,550 bp (86 predicted genes) for the Bxb1 genome. PA6 infected only P. acnes and produced clear plaques with turbid centers, but it lacked any obvious genes for lysogeny. The host range of PA6 was restricted to P. acnes, but the phage was able to infect and lyse all P. acnes isolates tested. Sequencing of the PA6 genome makes an important contribution to the study of phage evolution and propionibacterial genetics