13,166 research outputs found
Integration of an aerosol-assisted deposition technique for the deposition of functional biomaterials applied to the fabrication of miniaturised Ion sensors
Ion-selective electrodes are at the forefront of research nowadays, with applications in healthcare, agriculture and water quality analysis among others. Despite multiple attempts of miniaturization of these polyvinyl chloride (PVC) gel-based ion sensors, no ion-sensing devices with a thickness below the micrometer range, and operating using open circuit potential, have been developed so far. This work reports the causes of this thickness limitation in potassium-selective sensors. Highly homogeneous ion-sensing films were fabricated by a method based on aerosol assisted chemical vapour deposition, leading to smooth surfaces with 27 ± 11 nm of roughness. Such homogeneity allowed the systematic study of the performance and ionic diffusion properties of the sensing films at sub-micrometer scales. Sensitivities below the Nernst response were found at low thicknesses. The nature of this reduction in sensitivity was studied, and a difference in the superficial and bulk compositions of the films was measured. An optimal configuration was found at 15 µm, with a good selectivity against Na+ (KK+, Na+ = −1.8) a limit of detection in the range of 10−4 M and esponse time below 40 s. The stability of sensors was improved by the deposition of protective layers, which expanded the lifespan of the ion sensors up to 5 weeks while preserving the Nernst sensitivity
Rapid detection of free and bound toxins using molecularly imprinted silica/graphene oxide hybrids dagger
Rapid, selective detection of biological analytes is necessary for early diagnosis, but is often complicated by the analytes being bound to proteins and the lack of fast and reliable systems available for their direct assessment. Here, a cheap, easily-assembled molecularly imprinted silica/graphene oxide hybrid is developed, which can selectively detect toxins linked to early-stage chronic kidney disease, down to femtomolar concentrations within 5 minutes. The hybrid material is capable of simultaneously and separately measuring free and bound analytes using with an ultra-low limit of detection in the femtomolar range, and uses processes intrinsically adaptable to any charged molecular analy
Landscape Assessment via Regression Analysis
This paper presents a methodology for assessing the visual quality of agricultural landscapes through direct and indirect techniques of landscape valuation. The first technique enables us to rank agricultural landscapes on the basis of a survey of public preferences. The latter weighs the contribution of the elements and attributes contained in the picture to its overall scenic beauty via regression analysis. The photos used in the survey included man-made elements, positive and negative, agricultural fields, mainly of cereals and olive trees, and a natural park. The results show that perceived visual quality increases, in decreasing order of importance, with the degree of wilderness of the landscape, the presence of well-preserved man-made elements, the percentage of plant cover, the amount of water, the presence of mountains and the colour contrast.landscape assessment, visual quality, landscape elements, landscape value, Land Economics/Use, H41, Q21, Q26,
Molecular analysis of estrogen receptor alpha gene AGATA haplotype and SNP12 in European populations: potential protective effect for cryptorchidism and lack of association with male infertility.
PO-0815: Impact of digitizer response and time averaging de-noising in radiochromic film dosimetry
Boundary K-Matrices for the Six Vertex and the n(2n-1) A_{n-1} Vertex Models
Boundary conditions compatible with integrability are obtained for two
dimensional models by solving the factorizability equations for the reflection
matrices . For the six vertex model the general solution
depending on four arbitrary parameters is found. For the models all
diagonal solutions are found. The associated integrable magnetic Hamiltonians
are explicitly derived.Comment: 9 pages,latex, LPTHE-PAR 92-4
Analysis of CMB maps with 2D wavelets
We consider the 2D wavelet transform with two scales to study sky maps of
temperature anisotropies in the cosmic microwave background radiation (CMB). We
apply this technique to simulated maps of small sky patches of size 12.8 \times
12.8 square degrees and 1.5' \times 1.5' pixels. The relation to the standard
approach, based on the cl's is established through the introduction of the
scalogram. We consider temperature fluctuations derived from standard, open and
flat-Lambda CDM models. We analyze CMB anisotropies maps plus uncorrelated
Gaussian noise (uniform and non-uniform) at idfferent S/N levels. We explore in
detail the denoising of such maps and compare the results with other techniques
already proposed in the literature. Wavelet methods provide a good
reconstruction of the image and power spectrum. Moreover, they are faster than
previously proposed methods.Comment: latex file 7 pages + 5 postscript files + 1 gif file; accepted for
publication in A&A
PCN4 Costo-Efectividad De Octreotide Comparado Con Terapia De Soporte Usual Para El Tratamiento De Tumores Neuroendocrinos En Colombia
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