1,239 research outputs found

    Dirac parameters and topological phase diagram of Pb1-xSnxSe from magneto-spectroscopy

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    Pb1-xSnxSe hosts 3D massive Dirac fermions across the entire composition range for which the crystal structure is cubic. In this work, we present a comprehensive experimental mapping of the 3D band structure parameters of Pb1-xSnxSe as a function of composition and temperature. We cover a parameter space spanning the band inversion that yields its topological crystalline insulator phase. A non-closure of the energy gap is evidenced in the vicinity of this phase transition. Using magnetooptical Landau level spectroscopy, we determine the energy gap, Dirac velocity, anisotropy factor and topological character of Pb1-xSnxSe epilayers grown by molecular beam epitaxy on BaF2 (111). Our results are evidence that Pb1-xSnxSe is a model system to study topological phases and the nature of the phase transition.Comment: Submitte

    Molecular Imaging in Synthetic Biology, and Synthetic Biology in Molecular Imaging

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    Biomedical synthetic biology is an emerging field in which cells are engineered at the genetic level to carry out novel functions with relevance to biomedical and industrial applications. This approach promises new treatments, imaging tools, and diagnostics for diseases ranging from gastrointestinal inflammatory syndromes to cancer, diabetes, and neurodegeneration. As these cellular technologies undergo pre-clinical and clinical development, it is becoming essential to monitor their location and function in vivo, necessitating appropriate molecular imaging strategies, and therefore, we have created an interest group within the World Molecular Imaging Society focusing on synthetic biology and reporter gene technologies. Here, we highlight recent advances in biomedical synthetic biology, including bacterial therapy, immunotherapy, and regenerative medicine. We then discuss emerging molecular imaging approaches to facilitate in vivo applications, focusing on reporter genes for noninvasive modalities such as magnetic resonance, ultrasound, photoacoustic imaging, bioluminescence, and radionuclear imaging. Because reporter genes can be incorporated directly into engineered genetic circuits, they are particularly well suited to imaging synthetic biological constructs, and developing them provides opportunities for creative molecular and genetic engineering

    Massive and massless Dirac fermions in Pb1-xSnxTe topological crystalline insulator probed by magneto-optical absorption

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    Dirac fermions in condensed matter physics hold great promise for novel fundamental physics, quantum devices and data storage applications. IV-VI semiconductors, in the inverted regime, have been recently shown to exhibit massless topological surface Dirac fermions protected by crystalline symmetry, as well as massive bulk Dirac fermions. Under a strong magnetic field (B), both surface and bulk states are quantized into Landau levels that disperse as B^1/2, and are thus difficult to distinguish. In this work, magneto-optical absorption is used to probe the Landau levels of high mobility Bi-doped Pb0.54Sn0.46Te topological crystalline insulator (111)-oriented films. The high mobility achieved in these thin film structures allows us to probe and distinguish the Landau levels of both surface and bulk Dirac fermions and extract valuable quantitative information about their physical properties. This work paves the way for future magnetooptical and electronic transport experiments aimed at manipulating the band topology of such materials.Comment: supplementary material included, to appear in Scientific Report

    Antiferromagnetic phase of the gapless semiconductor V3Al

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    Discovering new antiferromagnetic compounds is at the forefront of developing future spintronic devices without fringing magnetic fields. The antiferromagnetic gapless semiconducting D03 phase of V3Al was successfully synthesized via arc-melting and annealing. The antiferromagnetic properties were established through synchrotron measurements of the atom-specific magnetic moments, where the magnetic dichroism reveals large and oppositely-oriented moments on individual V atoms. Density functional theory calculations confirmed the stability of a type G antiferromagnetism involving only two-third of the V atoms, while the remaining V atoms are nonmagnetic. Magnetization, x-ray diffraction and transport measurements also support the antiferromagnetism. This archetypal gapless semiconductor may be considered as a cornerstone for future spintronic devices containing antiferromagnetic elements.Comment: Accepted to Physics Review B on 02/23/1

    Overlap properties of geometric expanders

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    The {\em overlap number} of a finite (d+1)(d+1)-uniform hypergraph HH is defined as the largest constant c(H)(0,1]c(H)\in (0,1] such that no matter how we map the vertices of HH into Rd\R^d, there is a point covered by at least a c(H)c(H)-fraction of the simplices induced by the images of its hyperedges. In~\cite{Gro2}, motivated by the search for an analogue of the notion of graph expansion for higher dimensional simplicial complexes, it was asked whether or not there exists a sequence {Hn}n=1\{H_n\}_{n=1}^\infty of arbitrarily large (d+1)(d+1)-uniform hypergraphs with bounded degree, for which infn1c(Hn)>0\inf_{n\ge 1} c(H_n)>0. Using both random methods and explicit constructions, we answer this question positively by constructing infinite families of (d+1)(d+1)-uniform hypergraphs with bounded degree such that their overlap numbers are bounded from below by a positive constant c=c(d)c=c(d). We also show that, for every dd, the best value of the constant c=c(d)c=c(d) that can be achieved by such a construction is asymptotically equal to the limit of the overlap numbers of the complete (d+1)(d+1)-uniform hypergraphs with nn vertices, as nn\rightarrow\infty. For the proof of the latter statement, we establish the following geometric partitioning result of independent interest. For any dd and any ϵ>0\epsilon>0, there exists K=K(ϵ,d)d+1K=K(\epsilon,d)\ge d+1 satisfying the following condition. For any kKk\ge K, for any point qRdq \in \mathbb{R}^d and for any finite Borel measure μ\mu on Rd\mathbb{R}^d with respect to which every hyperplane has measure 00, there is a partition Rd=A1Ak\mathbb{R}^d=A_1 \cup \ldots \cup A_{k} into kk measurable parts of equal measure such that all but at most an ϵ\epsilon-fraction of the (d+1)(d+1)-tuples Ai1,,Aid+1A_{i_1},\ldots,A_{i_{d+1}} have the property that either all simplices with one vertex in each AijA_{i_j} contain qq or none of these simplices contain qq

    A Pair of Disjoint 3-GDDs of type g^t u^1

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    Pairwise disjoint 3-GDDs can be used to construct some optimal constant-weight codes. We study the existence of a pair of disjoint 3-GDDs of type gtu1g^t u^1 and establish that its necessary conditions are also sufficient.Comment: Designs, Codes and Cryptography (to appear

    Miniband engineering and topological phase transitions in topological - normal insulator superlattices

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    Periodic stacking of topologically trivial and non-trivial layers with opposite symmetry of the valence and conduction bands induces topological interface states that, in the strong coupling limit, hybridize both across the topological and normal insulator layers. Using band structure engineering, such superlattices can be effectively realized using the IV-VI lead tin chalcogenides. This leads to emergent minibands with a tunable topology as demonstrated both by theory and experiments. The topological minibands are proven by magneto-optical spectroscopy, revealing Landau level transitions both at the center and edges of the artificial superlattice mini Brillouin zone. Their topological character is identified by the topological phase transitions within the minibands observed as a function of temperature. The critical temperature of this transition as well as the miniband gap and miniband width can be precisely controlled by the layer thicknesses and compositions. This witnesses the generation of a new fully tunable quasi-3D topological state that provides a template for realization of magnetic Weyl semimetals and other strongly interacting topological phases.Comment: 21 pages, 8 figure

    First Passage Distributions in a Collective Model of Anomalous Diffusion with Tunable Exponent

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    We consider a model system in which anomalous diffusion is generated by superposition of underlying linear modes with a broad range of relaxation times. In the language of Gaussian polymers, our model corresponds to Rouse (Fourier) modes whose friction coefficients scale as wavenumber to the power 2z2-z. A single (tagged) monomer then executes subdiffusion over a broad range of time scales, and its mean square displacement increases as tαt^\alpha with α=1/z\alpha=1/z. To demonstrate non-trivial aspects of the model, we numerically study the absorption of the tagged particle in one dimension near an absorbing boundary or in the interval between two such boundaries. We obtain absorption probability densities as a function of time, as well as the position-dependent distribution for unabsorbed particles, at several values of α\alpha. Each of these properties has features characterized by exponents that depend on α\alpha. Characteristic distributions found for different values of α\alpha have similar qualitative features, but are not simply related quantitatively. Comparison of the motion of translocation coordinate of a polymer moving through a pore in a membrane with the diffusing tagged monomer with identical α\alpha also reveals quantitative differences.Comment: LaTeX, 10 pages, 8 eps figure

    Reduction of quantum noise in optical interferometers using squeezed light

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    We study the photon counting noise in optical interferometers used for gravitational wave detection. In order to reduce quantum noise a squeezed vacuum state is injected into the usually unused input port. Here, we specifically investigate the so called `dark port case', when the beam splitter is oriented close to 90{\deg} to the incoming laser beam, such that nearly all photons go to one output port of the interferometer, and only a small fraction of photons is seen in the other port (`dark port'). For this case it had been suggested that signal amplification is possible without concurrent noise amplification [R.Barak and Y.Ben-Aryeh, J.Opt.Soc.Am.B25(361)2008]. We show that by injection of a squeezed vacuum state into the second input port, counting noise is reduced for large values of the squeezing factor, however the signal is not amplified. Signal strength only depends on the intensity of the laser beam.Comment: 8 pages, 1 figur

    Patient-Led Research Collaborative: embedding patients in the Long COVID narrative

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    A large subset of patients with coronavirus disease 2019 (COVID-19) are experiencing symptoms well beyond the claimed 2-week recovery period for mild cases. These long-term sequelae have come to be known as Long COVID. Originating out of a dedicated online support group, a team of patients formed the Patient-Led Research Collaborative and conducted the first research on Long COVID experience and symptoms. This article discusses the history and value of patient-centric and patient-led research; the formation of Patient-Led Research Collaborative as well as key findings to date; and calls for the following: the acknowledgement of Long COVID as an illness, an accurate estimate of the prevalence of Long COVID, publicly available basic symptom management, care, and research to not be limited to those with positive polymerase chain reaction and antibody tests, and aggressive research and investigation into the pathophysiology of symptoms
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