EFFECTS OF ENERGETIC THERAPY ON BASAL CELL CARCINOMA

This pilot study examines the effect of the application of energetic therapy by two energy practitioners nationally recognized for their effectiveness on basal cell carcinoma BCe. Outcome measures included photographs of the tumors during the treatment process, referring physician follow-up reports, and patient reports. Change in tumor size was related to simultaneously measured variables including therapist assessments of client's energy condition and therapist outcome expectation, and client gender, depression, mood, and outcome expectation. Client quality of life at the conclusion of treatment was assessed based on criteria for evaluating nonconventional cancer treatments from the Office of Technology Assessment (OTA). Adverse effects and cost-effectiveness of the treatment were examined. Advantage of studying treatment of this disease in complementary medicine research is noted

Herd specific risk factors for Mycoplasma hyopneumoniae infections in suckling pigs at the age of weaning

BACKGROUND Mycoplasma hyopneumoniae is the etiologic agent of enzootic pneumonia mainly occurring in fattening pigs. It is assumed that horizontal transmission of the pathogen during nursery and growing phase starts with few suckling pigs vertically infected by the sow. The aim of the present study was the exploration of the herd prevalence of M. hyopneumoniae infections in suckling pigs followed by an investigation of various herd specific factors for their potential of influencing the occurrence of this pathogen at the age of weaning. RESULTS In this cross-sectional study, 125 breeding herds were examined by taking nasal swabs from 20 suckling pigs in each herd. In total, 3.9% (98/2500) of all nasal swabs were tested positive for M. hyopneumoniae by real-time PCR. Piglets tested positive originated from 46 different herds resulting in an overall herd prevalence of 36.8% (46/125) for M. hyopneumoniae infection in pigs at the age of weaning. While the herds were epidemiologically characterized, the risk for demonstration of M. hyopneumoniae was significantly increased, when the number of purchased gilts per year was more than 120 (OR: 5.8), and when the number of farrowing pens per compartment was higher than 16 (OR: 3.3). In herds with a planned and segregated production, where groups of sows entered previously emptied farrowing units, the risk for demonstration of M. hyopneumoniae in piglets was higher in herds with two or four weeks between batches than in herds with one or three weeks between batches (OR: 2.7). CONCLUSIONS In this cross-sectional study, several risk factors could be identified enhancing the probability of breeding herds to raise suckling pigs already infected with M. hyopneumoniae at the time of weaning. Interestingly, some factors (farrowing rhythm, gilt acclimatisation issues) were overlapping with those also influencing the seroprevalences among sows or the transmission of the pathogen between older age groups. Taking the multifactorial character of enzootic pneumonia into account, the results of this study substantiate that a comprehensive herd specific prevention programme is a prerequisite to reduce transmission of and disease caused by M. hyopneumoniae

Food safety metrics relevant to low- and middle-income countries

London School of Hygiene and Tropical MedicineRoyal Veterinary College, LondonWorld Health OrganizationFood and Agriculture Organization of the United Nation

The Fornax3D project: Environmental effects on the assembly of dynamically cold disks in Fornax cluster galaxies

We apply a population-orbit superposition method to 16 galaxies in the Fornax cluster observed with MUSE/VLT in the context of the Fornax3D project. By fitting the luminosity distribution, stellar kinematics, and age and metallicity maps simultaneously, we obtained the internal stellar orbit distribution, as well as the age and metallicity distribution of stars on different orbits for each galaxy. Based on the model, we decompose each galaxy into a dynamically cold disk (orbital circularity $\lambda_z\ge0.8$) and a dynamically hot non-disk component (orbital circularity $\lambda_z<0.8$), and obtain the surface-brightness, age, and metallicity radial profiles of each component. The galaxy infall time into the cluster is strongly correlated with galaxy cold-disk age with older cold disks in ancient infallers. We quantify the infall time $t_{\rm infall}$ of each galaxy with its cold-disk age using a correlation calibrated with TNG50 cosmological simulations. For galaxies in the Fornax cluster, we found that the luminosity fraction of cold disk in galaxies with $t_{\rm infall}>8$ Gyr are a factor of $\sim 4$ lower than in more recent infallers while controlling for total stellar mass. Nine of the 16 galaxies have spatially extended cold disks, and most of them show positive or zero age gradients; stars in the inner disk are $\sim 2-5$ Gyr younger than that in the outer disk, in contrast to the expectation of inside-out growth. Our results indicate that the assembly of cold disks in galaxies is strongly affected by their infall into clusters, by either removal of gas in outer regions or even tidally stripping or heating part of the pre-existing disks. Star formation in outer disks can stop quickly after the galaxy falls into the cluster, while star formation in the inner disks can last for a few Gyrs more, building the positive age gradient measured in cold disks.Comment: 31 pages, 32 figures, Accepted to A&

Looking into the faintEst WIth MUSE (LEWIS): on the nature of ultra-diffuse galaxies in the Hydra-I cluster.I. Project description and preliminary results

Looking into the faintEst WIth MUSE (LEWIS) is an ESO large observing programme aimed at obtaining the first homogeneous integral-field spectroscopic survey of 30 extremely low-surface brightness (LSB) galaxies in the Hydra I cluster of galaxies, with MUSE at ESO-VLT. The majority of LSB galaxies in the sample (22 in total) are ultra-diffuse galaxies (UDGs). The distribution of systemic velocities Vsys ranges between 2317 km/s and 5198 km/s and is centred on the mean velocity of Hydra I (Vsys = 3683 $\pm$ 46 km/s). Considering the mean velocity and the velocity dispersion of the cluster, 17 out of 20 targets are confirmed cluster members. To assess the quality of the data and demonstrate the feasibility of the science goals, we report the preliminary results obtained for one of the sample galaxies, UDG11. For this target, we derived the stellar kinematics, including the 2-dimensional maps of line-of-sight velocity and velocity dispersion, constrained age and metallicity, and studied the globular cluster (GC) population hosted by the UDG. Results are compared with the available measurements for UDGs and dwarf galaxies in literature. By fitting the stacked spectrum inside one effective radius, we find that UDG11 has a velocity dispersion $\sigma = 20 \pm 8$ km/s, it is old ($10\pm1$ Gyr), metal-poor ([M/H]=-1.17$\pm$0.11 dex) and has a total dynamical mass-to-light ratio M$/L_V\sim 14$, comparable to those observed for classical dwarf galaxies. The spatially resolved stellar kinematics maps suggest that UDG11 does not show a significant velocity gradient along either major or minor photometric axes. We find two GCs kinematically associated with UDG11. The estimated total number of GCs in UDG11, corrected for the spectroscopic completeness limit, is $N_{GC}= 5.9^{+2.2}_ {-1.8}$, which corresponds to a GC specific frequency of $S_N = 8.4^{+3.2}_{-2.7}$.Comment: Accepted for publication in Astronomy and Astrophysic