246 research outputs found

    Food Insecurity and Psychological Well-Being Among Women Living with HIV/AIDS on Antiretroviral Therapy in the Alabama Black Belt

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    The objective of this research was to estimate the prevalence of food insecurity and determine if food insecurity is associated with psychological well-being among women living with HIV/AIDS. Survey data were collected from 268 women living with HIV/AIDS attending two clinics that provide medical and social support services to HIV-positive patients who live in 23 counties in Southeast Alabama. The results indicated that, using USDA food security scale, 54% of the women were food insecure. Multiple regression analysis results indicated that income, depressive symptoms, race, and participation in SNAP were significant predictors of food insecurity; employment and education were not statistically significant predictors. The overall model was significant at the 5% level reflecting the validity of the model. Based on these results, programs that address food insecurity should be a critical component of HIV/AIDS treatment in the Alabama Black Belt

    Factors Associated with Belief in Conspiracies about HIV/AIDS among HIV-Positive African-American Patients

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    Abstract The purpose of this study is to examine factors associated with belief in conspiracies about HIV/AIDS among HIV-Positive African American patients. Survey data were collected from 256 African American patients living with HIV/AIDS attending two HIV clinics in Montgomery and Dothan, Alabama. The study used multiple regression analysis to examine how sociodemographic factors contribute to belief in conspiracies about HIV/AIDS. Education and age were significantly related to belief in conspiracies about HIV/AIDS among men and women. Beliefs in conspiracies about HIV/AIDS may be a barrier to HIV prevention among African Americans. Public health officials should work toward obtaining the trust of African Americans by addressing the existing discrimination within the health care system and acknowledging the existence of HIV/AIDS conspiracy beliefs. Conspiracies about HIV/AIDS may be a manifestation to African Americans’ mistrust of the U.S. government and the health system. Keywords: HIV/AIDS, African Americans, Conspiracy Belief

    Evaluation de l’introgression du caractĂšre croissance lente de quelques gĂ©niteurs Akpadanou (origine BĂ©nin) chez quelques gĂ©niteurs amĂ©liorĂ©s de palmier Ă  huile (E. guineensis Jacq.) de l’origine La MĂ© (CĂŽte d’Ivoire)

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    La vitesse de croissance en hauteur de 294 arbres appartenant Ă  11 descendances de palmier Ă  huile a étĂ© Ă©valuĂ©e selon la mĂ©thode dĂ©crite par Jacquemard (1980). Ces descendances ont Ă©tĂ© obtenues Ă  partir de plusieurs croisements de type (AKN3 x La MĂ©) x La MĂ© et (AKN3 x La MĂ©) x (La MĂ© x La MĂ©) qui visaient à introduire le caractĂšre croissance lente de l’origine Akpadanou (Benin) chez des gĂ©niteurs amĂ©liorĂ©s de l’origine La MĂ©, CĂŽte d’Ivoire. Les descendances ont Ă©tĂ© comparĂ©es Ă  un tĂ©moin vulgarisĂ© de type DA10D x LM2T. Les rĂ©sultats ont montrĂ© que l’ensemble des descendances testĂ©es ont une vitesse de croissance en hauteur moyenne infĂ©rieure au tĂ©moin. En effet, les valeurs obtenues ont variĂ© de 19,86 Ă  35,89 cm/an au sein de ces descendances testĂ©es, contre 45,25 cm/an pour le tĂ©moin de l’essai. Une rĂ©duction de plus de 20% de la vitesse de croissance en hauteur a donc Ă©tĂ© observĂ©e au niveau de ces descendances. Ces rĂ©sultats laissent entrevoir la perspective de sĂ©lection, Ă  terme, de matĂ©riel vĂ©gĂ©tal Ă  croissance en hauteur fortement rĂ©duite et possĂ©dant un bon niveau de production de rĂ©gimes et d’huile de palme.Mots clĂ©s : SĂ©lection, palmier amĂ©liorĂ©, croissance en hauteur rĂ©duite

    Inhibitive effects of 2-mercaptobenzimidazole (MBI) and 2-thiobenzylbenzimidazole (TBBI) on copper corrosion in 1 M nitric acid solution

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    The inhibitive actions of 2-mercaptobenzimidazole (MBI) and 2-thiobenzylbenzimidazole (TBBI) on copper corrosion in 1M HNO3 medium were studied, using weight loss method, at 25 to 65°C and concentrations of 5.10-5M to 10-3M. The results showed that the two compounds had fairly good inhibiting properties for copper corrosion in the medium, with efficiencies of 90.0% for TBBI and 87.7% for MBI at 25°C and concentration of 10-3M. Modified Langmuir isotherm was found to provide an accurate description of the behavior of the two compounds. The thermodynamic functions of adsorption (ΔG°ads,Qads) and the activation energy (Ea) were calculated. Negative values of changes in free energies were obtained, indicating the spontaneity of the adsorption process. From thermodynamic adsorption and dissolution functions, both physisorption and chemisorption were proposed. Quantum chemical parameters such as highest occupied molecular orbital energy (EHOMO), lowest unoccupied molecular orbital energy (ELUMO), energy gap (ΔE) and dipole moment (μ) were calculated for these compounds, using DFT/B3LYP/6-31G (d,p) method in order to discuss the correlation between theoretical data and experimental results. It was found that theoretical data support the experimental results.Key words: Corrosion Inhibitor, inhibition efficiency, adsorption isotherm, free adsorption energy, adsorption heat, theoretical calculation, dipole moment

    The use of sequential mark-release-recapture experiments to estimate population size, survival and dispersal of male mosquitoes of the  Anopheles gambiae complex in Bana, a west African humid savannah village

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    BACKGROUND: Vector control is a major component of the malaria control strategy. The increasing spread of insecticide resistance has encouraged the development of new tools such as genetic control which use releases of modified male mosquitoes. The use of male mosquitoes as part of a control strategy requires an improved understanding of male mosquito biology, including the factors influencing their survival and dispersal, as well as the ability to accurately estimate the size of a target mosquito population. This study was designed to determine the seasonal variation in population size via repeated mark-release-recapture experiments and to estimate the survival and dispersal of male mosquitoes of the Anopheles gambiae complex in a small west African village. METHODS: Mark-release-recapture experiments were carried out in Bana Village over two consecutive years, during the wet and the dry seasons. For each experiment, around 5000 (3407-5273) adult male Anopheles coluzzii mosquitoes were marked using three different colour dye powders (red, blue and green) and released in three different locations in the village (centre, edge and outside). Mosquitoes were recaptured at sites spread over the village for seven consecutive days following the releases. Three different capture methods were used: clay pots, pyrethroid spray catches and swarm sampling. RESULTS: Swarm sampling was the most productive method for recapturing male mosquitoes in the field. Population size and survival were estimated by Bayesian analyses of the Fisher-Ford model, revealing an about 10-fold increase in population size estimates between the end of dry season (10,000-50,000) to the wet season (100,000-500,000). There were no detectable seasonal effects on mosquito survival, suggesting that factors other than weather may play an important role. Mosquito dispersal ranged from 40 to 549 m over the seven days of each study and was not influenced by the season, but mainly by the release location, which explained more than 44% of the variance in net dispersal distance. CONCLUSION: This study clearly shows that male-based MRR experiments can be used to estimate some parameters of wild male populations such as population size, survival, and dispersal and to estimate the spatial patterns of movement in a given locality

    Heterosis Increases Fertility, Fecundity and Survival of Laboratory-Produced F1 Hybrid Males of the Malaria Mosquito Anopheles coluzzii

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    The success of vector control strategies aiming to decrease disease transmission via the release of sterile or genetically-modified male mosquitoes critically depends on mating between laboratory-reared males and wild females. Unfortunately, mosquito colonization, laboratory rearing, and genetic manipulations can all negatively affect male competitiveness. Heterosis is commonly used to produce domestic animals with enhanced vigor and homogenous genetic background and could therefore potentially improve the mating performance of mass-reared male mosquitoes. Here, we produced enhanced hybrid males of the malaria mosquito Anopheles coluzzii by crossing two strains colonized 35+ and 8 years ago. We compared the amount of sperm and mating plug proteins they transferred to females, as well as their insemination rate, reproductive success and longevity under various experimental conditions. Across experiments widespread adaptations to laboratory mating were detected in the older strain. In large-group mating experiments, no overall hybrid advantage in insemination rates and the amount of sperm and accessory gland proteins transferred to females was detected. Despite higher sperm activity, hybrid males did not appear more fecund. However, individual-male mating and laboratory-swarm experiments revealed that hybrid males, while inseminating fewer females than older inbred males, were significantly more fertile, producing larger mating plugs and drastically increasing female fecundity. Heterotic males also showed increased longevity. These results validate the use of heterosis for creating hybrid males with improved fitness from long-established inbred laboratory strains. Therefore, this simple approach could facilitate disease control strategies based on male mosquito releases with important ultimate benefits to human health

    Étude de l’influence du facteur antĂ©cĂ©dent cultural palmiers et cocotiers sur l’évolution de la fusariose vasculaire chez six clones de palmiers Ă  huile de CĂŽte d’Ivoire

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    Objectif : La fusariose vasculaire du palmier Ă  huile, causĂ©e par le champignon Fusarium oxysporum f.sp. elaeidis, est une contrainte pathologique majeure pour la culture du palmier Ă  huile en Afrique, notamment en CĂŽte d’Ivoire. Dans la zone dite « savane de Dabou », en CĂŽte d’Ivoire oĂč la maladie sĂ©vit de maniĂšre endĂ©mique, les travaux de recherche de lutte intĂ©grĂ©e Ă  la fusariose, ont Ă©tĂ© rĂ©alisĂ©s dans le cadre de cette Ă©tude sur des parcelles Ă  antĂ©cĂ©dent cultural cocotier ou palmier. Aussi, notre Ă©tude a-t-elle pour objectif gĂ©nĂ©ral de confirmer les rĂ©sultats de recherche obtenus pour l’amĂ©lioration du matĂ©riel vĂ©gĂ©tal en vue de minimiser l’impact de la fusariose en CĂŽte d’Ivoire. SpĂ©cifiquement, il s’est agi d’étudier l’évolution de la fusariose d’une part, et d’analyser cette Ă©volution selon l’antĂ©cĂ©dent cultural d’autre part.MĂ©thodologie et rĂ©sultats : L’étude a portĂ© sur l’observation des symptĂŽmes de fusariose cumulĂ©e et du taux de rĂ©mission de la fusariose des plants de palmier plantĂ©s de 1990 Ă  2013 sur antĂ©cĂ©dents cocotiers et palmers fusariĂ©s. Ainsi, pour la premiĂšre fois, nos rĂ©sultats rĂ©vĂšlent que les palmiers replantĂ©s sur antĂ©cĂ©dents cocotiers manifestent plus rapidement la fusariose que ceux plantĂ©s sur antĂ©cĂ©dents palmiers. Il est donc possible que les souches et les racines des cocotiers conservent le champignon pathogĂšne de la premiĂšre gĂ©nĂ©ration de palmiers fusariĂ©s constituant par consĂ©quent une source d’inoculum lors des replantations.Conclusion et application des rĂ©sultats : Les sites Ă  antĂ©cĂ©dents culturaux cocotier ne constituent pas un environnement agro Ă©cologique favorable pour la culture des plants de palmiers Ă  huile sensibles Ă  la fusariose. Il est souhaitable d’utiliser des plants tolĂ©rants pour la mise en place de palmeraies industrielles.Mots clĂ©s : Palmier Ă  huile, Cocotier, Fusarium oxysporum f.sp elaeidis, Clone, AntĂ©cĂ©dent cultural

    Extinction time for some nonlinear heat equations

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    This paper concerns the study of the extinction time of the solution of the following initial-boundary value problem [left{% begin{array}{ll} hbox{ut=varepsilonLu(x,t)−f(u)quadmboxinquadOmegatimesmathbbR+u_t=varepsilon Lu(x,t)-f(u)quad mbox{in}quad Omegatimesmathbb{R}_{+},} \ hbox{u(x,t)=0quadmboxonquadpartialOmegatimesmathbbR+u(x,t)=0quad mbox{on}quadpartialOmegatimesmathbb{R}_{+},} \ hbox{u(x,0)=u0(x)>0quadmboxinquadOmegau(x,0)=u_{0}(x)>0quad mbox{in}quad Omega,} \ end{array}%right. ] where OmegaOmega is a bounded domain in mathbbRNmathbb{R}^{N} with smooth boundary partialOmegapartialOmega, varepsilonvarepsilon is a positive parameter, f(s)f(s) is a positive, increasing, concave function for positive values of s, f(0)=0f(0)=0, int0fracdsf(s)<+inftyint_{0}frac{ds}{f(s)}<+infty, LL is an elliptic operator. We show that the solution of the above problem extincts in a finite time and its extinction time goes to that of the solution alpha(t)alpha(t) of the following differential equation [alpha^{\u27}(t)=-f(alpha(t)),quad t>0,quad alpha(0)=M,] as varepsilonvarepsilon goes to zero, where M=supxinOmegau0(x)M=sup_{xin Omega}u_{0}(x). We also extend the above result to other classes of nonlinear parabolic equations. Finally, we give some numerical results to illustrate our analysis

    Target-site resistance mutations (kdr and RDL), but not metabolic resistance, negatively impact male mating competiveness in the malaria vector Anopheles gambiae

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    The implementation of successful insecticide resistance management strategies for malaria control is currently hampered by poor understanding of the ïŹtness cost of resistance on mosquito populations, including their mating competiveness. To ïŹll this knowledge gap, coupled and uncoupled Anopheles gambiae s.l. males (all M form (Anopheles coluzzii)) were collected from mating swarms in Burkina Faso. This multiple insecticide resistant population exhibited high 1014F kdrR allele frequencies (460%) and RDLR (480%) in contrast to the Ace-1R allele (o6%). Kdr heterozygote males were more likely to mate than homozygote resistant (OR=2.36; Po0.001), suggesting a negative impact of kdr on An. coluzzii mating ability. Interestingly, heterozygote males were also more competitive than homozygote susceptible (OR=3.26; P=0.006), suggesting a heterozygote advantage effect. Similarly, heterozygote RDLR/RDLS were also more likely to mate than homozygote-resistant males (OR=2.58; P=0.007). Furthermore, an additive mating disadvantage was detected in male homozygotes for both kdr/RDL-resistant alleles. In contrast, no ïŹtness difference was observed for the Ace-1 mutation. Comparative microarray-based genome-wide transcription analysis revealed that metabolic resistance did not signiïŹcantly alter the mating competitiveness of male An. coluzzii mosquitoes. Indeed, no signiïŹcant difference of expression levels was observed for the main metabolic resistance genes, suggesting that metabolic resistance has a limited impact on male mating competiveness. In addition, speciïŹc gene classes/GO terms associated with mating process were detected including sensory perception and peroxidase activity. The detrimental impact of insecticide resistance on mating competiveness observed here suggests that resistance management strategies such as insecticide rotation could help reverse the resistance, if implemented early

    Status of insecticide susceptibility in Anopheles arabiensis from Mwea rice irrigation scheme, Central Kenya

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    BACKGROUND: Control of the Anopheline mosquito vectors of malaria by use of insecticides has been shown to impact on both morbidity and mortality due to this disease. Evidence of insecticide resistance in different settings necessitates surveillance studies to allow prompt detection of resistance should it arise and thus enable its management. Possible resistance by Anopheles arabiensis mosquitoes from Mwea rice irrigation scheme in Central Kenya to insecticides in the four classes of insecticides approved by WHO for indoor residual spraying was investigated. METHODS: Susceptibility to DDT (an organochlorine), fenitrothion (an organophosphate), bendiocarb (a carbamate), lambdacyhalothrin and permethrin (both pyrethroids) was tested using standard WHO diagnostic bioassay kits. Bioassays were performed on non-blood fed mosquitoes one- to three-day old. Knockdown was recorded every 10 min and mortality 24 h post-exposure was noted. RESULTS: Mortality 24 h post-exposure was 100% for all insecticides except for lambdacyhalothrin, which averaged 99.46%. Knockdown rates at 10 min intervals were not significantly different between the Mwea population and the susceptible KISUMU strain of Anopheles gambiae sensu stricto control. The KDT(50 )and KDT(95 )values for the Mwea population were either lower than those for the control or higher by factors of no more than 2 for most comparisons and compared well with those of An. gambiae sensu lato categorized as susceptible in other studies. CONCLUSION: These results suggest that the Mwea population of An. arabiensis is susceptible to all the insecticides tested. This implies that vector control measures employing any of these insecticides would not be hampered by resistance
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