Beneficial use of immunoglobulins in the treatment of Sydenham chorea

This double case report indicates that treatment with intravenous immunoglobulins (IVIG) is effective in patients with Sydenham chorea (SC). SC is a rare but impressive clinical manifestation following streptococcal infection. This movement disorder characterised by chorea, emotional lability and muscle weakness, is one of the major criteria of acute rheumatic fever. Treatment of SC is typically limited to supportive care and palliative medications. Curative treatment is still in the experimental stage. Recent research on patients with SC proved that antibodies against the group A streptococcus cross-react with epitopes of neurons in the basal ganglia, namely, intracellular tubulin and extracellular lysoganglioside. Therefore, immune modulating therapy by means of prednisone, plasma exchange and IVIG are mentioned in the literature as possible effective treatment. Beneficial effect of IVIG has been shown in several diseases with molecular mimicry as the underlying pathophysiology. In this paper, we describe two girls aged 11 and 13 years, respectively, who presented with SC having severe disabilities in their daily live. We treated both patients with IVIG 400 mg/kg/day for 5 days. Treatment was tolerated well and had a pronounced positive effect. Shortly after the drug was administered, all signs and symptoms disappeared in both patients. Based upon these patients, we highlight IVIG as a serious treatment option for SC

Analysis of change in electric energy cost with using renewable energy sources in Gökceada, Turkey: An island example

In this study, electric requirement of Gökceada, the biggest island of Turkey is analyzed that how can it be supplied with renewable energy sources. In order to consider the optimal system configuration of hybrid or non-hybrid renewable energy system, the HOMER program is used. At relevant studies which are done about renewable energy sources, it is seen that cost analysis are done according to annual average values. But in this study, HOMER program is used in order to make the system which is generated with computer, as real as possible. On the other studies, it is found out that various changes which are occurred in the year cannot be added to the system. With HOMER; the effect of values which vary by the time like electric load, wind speed and solar radiation, is considered and than the electric system are modelled. For each of these data, 8760 values are formed in HOMER. HOMER cannot model transient changes which is smaller than 1 h. However; it is expressed that, hourly data are sufficient in order to analyze the system like this. In this study; systems which are composed of solar panels, wind turbines and batteries, auxiliary tools are modelled with considered various scenarios. Grid connection or diesel generators for backup power are also modelled. Values of components which form the renewable system of Gökceada, are determined by the simulations. The excess energy which occurs when the energy source is bigger than the load, can be sold to the grid and so, the cost of energy can be reduced. According to the simulation results; it is seen that, energy costs of wind energy systems are lower for Gökceada. It is revealed that wind energy is advantageous in Gökceada especially with grid sales according to the grid connected scenario.Renewable Energy Gokceada Wind Photovoltaic HOMER

Economic and Minimum Emission Dispatch

In this paper, Hopfield Neural Network (HNN) and Lagrange Multiplier (LM) solutions to economic dispatch (ED), NOx emission dispatch (EmD), and economic-emission dispatch (EED) of a sample system consisting of six thermal generators are presented. Transmission losses are included. The results of HNN are compared with the results of LM

Gelistirilmis Sinüs Kosinüs Algoritmasi Tabanli PID Kontrolör Kullanarak DC Motorun Hiz Kontrolü

3rd International Symposium on Multidisciplinary Studies and Innovative Technologies, ISMSIT 2019 -- 11 October 2019 through 13 October 2019 -- -- 156063Direct current (DC) motors that convert electrical energy into mechanical energy are used in almost every field of industry. Therefore, speed control of DC motor is very important and for this purpose generally proportional integral derivative (PID) controllers are preferred. In this study, it is aimed to improve the speed response of DC motor by designing a PID controller tuned by improved sine cosine algorithm (ISCA), namely the ISCA-PID controller. Unlike the original SCA and other meta-heuristic algorithms, the ISCA technique has balanced exploration and exploitation processes. The performance of the proposed ISCA-PID controller was compared with two current approaches in the literature in terms of transient response, frequency response and disturbance load response analyzes. The results of these analyzes confirmed the stability of the proposed ISCA-PID controller and its success in suppressing the disturbance loads. © 2019 IEEE

Benzetilmis Tavlamali Hibrit Balina Optimizasyon Algoritmasi Kullanarak Manyetik Top Aski Sisteminin Performans Artirimi

3rd International Symposium on Multidisciplinary Studies and Innovative Technologies, ISMSIT 2019 -- 11 October 2019 through 13 October 2019 -- -- 156063In this study, an efficient tuning method based on hybrid whale optimization algorithm with simulated annealing (WOA-SA) for optimum parameters setting of proportional integral derivative (PID) controller for magnetic ball suspension system is presented. High quality solutions can be achieved via WOA-SA algorithm with balanced local and global search capabilities. Comparative analyzes were conducted to evaluate the performance of the WOA-SA tuned PID controller designed to increase the stability profile of the system. The original whale optimization algorithm (WOA) and simulated annealing (SA) algorithm were used for performance comparison of the hybrid algorithm. The graphical and numerical results obtained from the convergence curve, transient response analysis and frequency response analysis showed that the proposed WOA-SA tuned system has a more stable structure. The essence and novelty of this study is the successful implementation of the proposed hybrid algorithm-based controller design procedure to the magnetic ball suspension system. © 2019 IEEE

The relationship of pain in patients with cervical arthrosis to sensory, flexibility and functional conditions

Aim: To investigate the relationship of the pain with sensory, flexibility and functional status in patients with chronic cervical arthrosis

Social accountability: A national framework for Turkish medical schools

WOS: 000588173500001PubMed: 33169641Purpose To define recommendations to the medical schools in Turkey about social accountability which meets the local needs. Methodology of the study the Association of Evaluation and Accreditation of Medical Education Programs (TEPDAD-Turkey) Social Accountability working group planned a study to determine national recommendations for social accountability of medical schools in two-stages. Delphi technique was used to develop the recommendations and finalize the recommendations in the first stage in which 61 members from 30 different institutions participated. Qualitative analysis was used for open questions in the first round and quantitative analysis for the data which is collected with a rating scale in the second and third rounds of the Delphi study. in the second stage, the recommendations were reviewed and finalized in a consensus workshop in which 68 members from 39 different institutions participated. Results in the Delphi study 63 recommendations were classified under five themes: the health needs of the society, health service delivery, institutional structure and management, educational program and implementation and development and evaluation of social accountability. in the consensus workshop, the 63 recommendations were evaluated and of which 54 of 63 recommendations were agreed upon. Conclusion A national framework has been developed by including a wide range of experts from different institutions for the social accountability of medical schools in Turkey. Developing recommendations in a local context will enhance the conceptualization of the recommendations of social accountability in the medical schools. As an accreditation body embedding the principles in the national standards will have a further impact on this process.Association for Accreditation and Evaluation of Medical Education Program (TEPDAD)This work was supported by Association for Accreditation and Evaluation of Medical Education Program (TEPDAD