Radio frequency emissions from dark-matter-candidate magnetized quark nuggets interacting with matter

Quark nuggets are theoretical objects composed of approximately equal numbers of up, down, and strange quarks. They are also called strangelets, nuclearites, AQNs, slets, Macros, and MQNs. Quark nuggets are a candidate for dark matter, which has been a mystery for decades despite constituting ~ 85% of the universe’s mass. Most previous models of quark nuggets have assumed no intrinsic magnetic field; however, Tatsumi found that quark nuggets may exist in magnetars as a ferromagnetic liquid with a magnetic field BS = 1012±1 T. We apply that result to quark nuggets, a dark-matter candidate consistent with the Standard Model, and report results of analytic calculations and simulations that show they spin up and emit electromagnetic radiation at ~ 104 to ~ 109 Hz after passage through planetary environments. The results depend strongly on the value of Bo, which is a parameter to guide and interpret observations. A proposed sensor system with three satellites at 51,000 km altitude illustrates the feasibility of using radio-frequency emissions to detect 0.003 to 1,600 MQNs, depending on Bo, during a 5 year mission

Gallium arsenide thermal conductivity and optical phonon relaxation times from first-principles calculations

In this paper, thermal conductivity of crystalline GaAs is calculated using first-principles lattice dynamics. The harmonic and cubic force constants are obtained by fitting them to the force-displacement data from density functional theory calculations. Phonon dispersion is calculated from a dynamical matrix constructed using the harmonic force constants and phonon relaxation times are calculated using Fermi's Golden rule. The calculated GaAs thermal conductivity agrees well with experimental data. Thermal conductivity accumulations as a function of the phonon mean free path and as a function of the wavelength are obtained. Our results predict a significant size effect on the GaAs thermal conductivity in the nanoscale. Relaxation times of optical phonons and their contributions from different scattering channels are also studied. Such information will help the understanding of hot phonon effects in GaAs-based devices.United States. Dept. of Energy. Office of Science (Award DE-SC0001299

Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

Candida albicans, the most common human pathogenic fungus, can establish a persistent lethal infection in the intestine of the microscopic nematode Caenorhabditis elegans. The C. elegans–C. albicans infection model was previously adapted to screen for antifungal compounds. Modifications to this screen have been made to facilitate a high-throughput assay including co-inoculation of nematodes with C. albicans and instrumentation allowing precise dispensing of worms into assay wells, eliminating two labor-intensive steps. This high-throughput method was utilized to screen a library of 3,228 compounds represented by 1,948 bioactive compounds and 1,280 small molecules derived via diversity-oriented synthesis. Nineteen compounds were identified that conferred an increase in C. elegans survival, including most known antifungal compounds within the chemical library. In addition to seven clinically used antifungal compounds, twelve compounds were identified which are not primarily used as antifungal agents, including three immunosuppressive drugs. This assay also allowed the assessment of the relative minimal inhibitory concentration, the effective concentration in vivo, and the toxicity of the compound in a single assay