11 research outputs found
Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors : a 12-month randomized controlled weight loss trial
Background: Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition
and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre.
Objective: To investigate the effects of a lupin-enriched diet, during and following energy restriction, on body weight and
composition and cardiovascular disease risk factors in overweight individuals.
Design: Participants (n=131) were recruited to a 12-month parallel-design trial. They were randomly assigned to consume
lupin-enriched foods or matching high-carbohydrate control foods. All participants underwent 3 months of weight loss,
1 month of weight stabilization and 8 months of weight maintenance. Body weight and composition and cardiovascular disease
risk factors were assessed at baseline, 4 and 12 months.
Results: Lupin, relative to control, did not significantly influence (mean difference (95% CI)) weight loss at 4 months (0.1 kg
(-1.2, 1.4)) and 12 months (-0.6 kg (-2.0, 0.8)), maintenance of weight loss from 4 to 12 months (-0.7 kg (-1.83, 0.48)) or
measures of body fat and fat-free mass. Relative to control, 24-h ambulatory systolic ( 1.3mmHg (-2.4, -0.3), P=0.016) and
diastolic (-1.0mmHg (-1.9, -0.2), P=0.021) blood pressures were lower at 12 months but not at 4 months; fasting
insulin concentrations and homeostasis model assessment (HOMA) scores were significantly lower at 4 months (-1.2mUlâ1
(-1.3, -1.1), P=0.004 and -0.6 units (-1.0, -0.19), P=0.004) and 12 months (-1.3 mUlâ1 (-1.4, -1.1), P<0.001 and
-0.7 units (-1.1, -0.24), P=0.002).
Conclusions: A diet higher in protein and fibre derived from lupin-enriched foods does not enhance weight loss or improve the
maintenance of weight loss. However, such a diet may provide cardiovascular health benefits in terms of insulin sensitivity and
blood pressure