11 research outputs found
Prevention and treatment effect of total flavonoids in Stellera chamaejasme L. on nonalcoholic fatty liver in rats
Paper 69: On the Shape of the Log Stress-Log Time Curve of Long Time Creep-Rupture Tests
Lupin Peptides Lower Low-Density Lipoprotein (LDL) Cholesterol through an Up-regulation of the LDL Receptor/Sterol Regulatory Element Binding Protein 2 (SREBP2) Pathway at HepG2 Cell Line
Health promoting properties of protein hydrolysates produced from oil palm (Elaeis guineensis) kernel
Isolated Conglutin Îł from Lupin, but not Phytate, Lowers Serum Cholesterol Without Influencing Vascular Lesion Development in the ApoE-deficient Mouse Model
Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors : a 12-month randomized controlled weight loss trial
Background: Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition
and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre.
Objective: To investigate the effects of a lupin-enriched diet, during and following energy restriction, on body weight and
composition and cardiovascular disease risk factors in overweight individuals.
Design: Participants (n=131) were recruited to a 12-month parallel-design trial. They were randomly assigned to consume
lupin-enriched foods or matching high-carbohydrate control foods. All participants underwent 3 months of weight loss,
1 month of weight stabilization and 8 months of weight maintenance. Body weight and composition and cardiovascular disease
risk factors were assessed at baseline, 4 and 12 months.
Results: Lupin, relative to control, did not significantly influence (mean difference (95% CI)) weight loss at 4 months (0.1 kg
(-1.2, 1.4)) and 12 months (-0.6 kg (-2.0, 0.8)), maintenance of weight loss from 4 to 12 months (-0.7 kg (-1.83, 0.48)) or
measures of body fat and fat-free mass. Relative to control, 24-h ambulatory systolic ( 1.3mmHg (-2.4, -0.3), P=0.016) and
diastolic (-1.0mmHg (-1.9, -0.2), P=0.021) blood pressures were lower at 12 months but not at 4 months; fasting
insulin concentrations and homeostasis model assessment (HOMA) scores were significantly lower at 4 months (-1.2mUlâ1
(-1.3, -1.1), P=0.004 and -0.6 units (-1.0, -0.19), P=0.004) and 12 months (-1.3 mUlâ1 (-1.4, -1.1), P<0.001 and
-0.7 units (-1.1, -0.24), P=0.002).
Conclusions: A diet higher in protein and fibre derived from lupin-enriched foods does not enhance weight loss or improve the
maintenance of weight loss. However, such a diet may provide cardiovascular health benefits in terms of insulin sensitivity and
blood pressure