4,063 research outputs found
Geometrical enhancement of the electric field: Application of fractional calculus in nanoplasmonics
We developed an analytical approach, for a wave propagation in
metal-dielectric nanostructures in the quasi-static limit. This consideration
establishes a link between fractional geometry of the nanostructure and
fractional integro-differentiation. The method is based on fractional calculus
and permits to obtain analytical expressions for the electric field
enhancement.Comment: Published in EP
Coherent photodissociation reactions: Observation by a novel picosecond polarization technique
In this communication, we wish to report on a novel picosecond polarization method for measuring the degree of rotational coherence that is preserved in photodissociation reactions. The systems studied here are jet-cooled van der Waals molecules; stilbene [4-6] bound [5] to He or Ne with a 1:1 composition.[7
Caging phenomena in reactions: Femtosecond observation of coherent, collisional confinement
We report striking observations of coherent caging of iodine, above the B state dissociation threshold, by single collisions with rare gas atoms at room-temperature. Despite the random nature of the solute–solvent interaction, the caged population retains coherence of the initially prepared unbound wave packet. We discuss some new concepts regarding dynamical coherent caging and the one-atom cage effect
Blockade of alpha 2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment
RATIONALE: Research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder demonstrated that chronic methylphenidate treatment during adolescence increased cocaine self-administration established during adulthood under a progressive ratio (PR) schedule. Compared to vehicle, chronic atomoxetine treatment during adolescence failed to increase cocaine self-administration under a PR schedule in adult SHR.
OBJECTIVES: We determined if enhanced noradrenergic transmission at α2-adrenergic receptors within prefrontal cortex contributes to this neutral effect of adolescent atomoxetine treatment in adult SHR.
METHODS: Following treatment from postnatal days 28–55 with atomoxetine (0.3 mg/kg) or vehicle, adult male SHR and control rats from Wistar-Kyoto (WKY) and Wistar (WIS) strains were trained to self-administer 0.3 mg/kg cocaine. Self-administration performance was evaluated under a PR schedule of cocaine delivery following infusion of the α2-adrenergic receptor antagonist idazoxan (0 and 10–56 μg/side) directly into prelimbic cortex.
RESULTS: Adult SHR attained higher PR break points and had greater numbers of active lever responses and infusions than WKY and WIS. Idazoxan dose-dependently increased PR break points and active lever responses in SHR following adolescent atomoxetine vs. vehicle treatment. Behavioral changes were negligible after idazoxan pretreatment in SHR following adolescent vehicle or in WKY and WIS following adolescent atomoxetine or vehicle.
CONCLUSIONS: α2-Adrenergic receptor blockade in prelimbic cortex of SHR masked the expected neutral effect of adolescent atomoxetine on adult cocaine self-administration behavior. Moreover, greater efficacy of acute idazoxan challenge in adult SHR after adolescent atomoxetine relative to vehicle is consistent with the idea that chronic atomoxetine may downregulate presynaptic α2A-adrenergic autoreceptors in SHR.National Institutes of Health grant DA011716. (DA011716 - National Institutes of Health)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693724/Published versio
A toy model of fractal glioma development under RF electric field treatment
A toy model for glioma treatment by a radio frequency electric field is
suggested. This low-intensity, intermediate-frequency alternating electric
field is known as the tumor-treating-field (TTF). In the framework of this
model the efficiency of this TTF is estimated, and the interplay between the
TTF and the migration-proliferation dichotomy of cancer cells is considered.
The model is based on a modification of a comb model for cancer cells, where
the migration-proliferation dichotomy becomes naturally apparent. Considering
glioma cancer as a fractal dielectric composite of cancer cells and normal
tissue cells, a new effective mechanism of glioma treatment is suggested in the
form of a giant enhancement of the TTF. This leads to the irreversible
electroporation that may be an effective non-invasive method of treating brain
cancer.Comment: Submitted for publication in European Physical Journal
Hole-hole interaction in a strained InGaAs two dimensional system
The interaction correction to the conductivity of 2D hole gas in strained
GaAs/InGaAs/GaAs quantum well structures was studied. It is shown
that the Zeeman splitting, spin relaxation and ballistic contribution should be
taking into account for reliable determination of the Fermi-liquid constant
. The proper consideration of these effects allows us to describe
both th temperature and magnetic field dependences of the conductivity and find
the value of .Comment: 7 pages, 6 figure
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