Analysis of the complications after ESWL in the treatment of renoureteral stones

IP USMF "Nicolae Testemiţanu", IMSP Spitalul Clinic Republican, Al VI-lea Congres de Urologie, Dializă şi Transplant Renal din Republica Moldova cu participare internaţională (21-23 octombrie 2015)Rezumat Aproximativ 80-90% din calculii reno-ureterali au ca indicaţie pentru tratament Litotriţia Extracorporeală cu unde de Şoc (ESWL). Fiind o procedură terapeutică, după ESWL pot apărea anumite complicaţii. Majoritatea complicaţiilor sunt minore, dar pot fi întâlnite şi complicaţii majore. Hematomul este o complicaţie gravă, dar are o frecvenţă scăzută. Pielonefrita acută apare în urma existenţei infecţiei sau datorită eliberării germenilor din calcul după fragmentare. Summary Approximately 80-90% of reno-ureteral stones have for treatment indication Extra Corporeal Shock Wave Lithotripsy (ESWL). Like a therapeutic procedure, extracorporeal lithotripsy may be accompanied by complications. Most of this complications are minor complications, but in a lower percentage, major complications can be appear. Hematoma is the most serious complication of extracorporeal lithotripsy, with a low incidence. Acute pyelonephritis (PNA) occurs either due to a pre-existing urinary infection, or by the release of germs located into the calculi during fragmentation

Our experience of the treatment of ureteral lithiasis in the Department of Urology SCM “Sf. Treime”

Secţia Urologie IMSPM SCM ”Sf.Treime”, Catedra de Urologie şi Nefrologie Chirurgicală USMF “N. Testemiţanu”, Al V-lea Congres de Urologie, Dializă şi Transplant Renal din Republica Moldova cu participare internaţională (1-13 iunie 2011)Summary Urolithiasis is one of the most widespread urological diseases, with incidence of not less than 3% of the population. The frequency of ureteral stones is at least 50% of cases urolithiasis. In this article was demonstrated our own experience and efficacy of own conduct of the treatment of ureteral lithiasis

The results of multicentric study of prostate pathology in some localities of Republic of Moldova

IP USMF "Nicolae Testemiţanu", IMSP Spitalul Clinic Republican, IMSP Spitalul Republican ACSR, IMSP SR Cahul, IMSP SR Edineţ, IMSP SR Drochia, IMSP SR Orhei, Compania farmaceutică Berline-Chemie Menarini, Reprezentanţa în R. Moldova, Al VI-lea Congres de Urologie, Dializă şi Transplant Renal din Republica Moldova cu participare internaţională (21-23 octombrie 2015)Rezumat. în lucrare sunt analizate rezultatele unui studiu multicentric a patologiei prostatei efectuat în baza screening-ului la bărbaţi din 7 localităţi ale R. Moldova. Conform protocolului adoptat au fost examinaţi 508 pacienţi cu vârsta medie de 63,3±9,1 ani. Au fost studiate structura patologiilor depistate (adenom de prostată (HBP), cancer de prostată (CP), prostatită), particularităţile clinice ale HBP, incidenţa CP, metodele de tratament recomandate în dependenţă de rezultatele screening-ului. Cea mai frecventă patologie a constituit HBP - 425 cazuri, sau 83,7%, în 8 cazuri (1,6%) a fost diagnosticat CP, iar prostatita cronică la 62 (12,2%) pacienţi. Majoritatea pacienţilor cu HBP - 76,8% au primit indicaţii pentru tratament conservator, 9,1% din pacienţi pentru prostatită cronică; tratamentul chirurgical a fost indicat la 30 pacienţi (5,9%) pentru HBP, iar tratament specializat pentru CP s-a indicat la 3 pacienţi (0,6%). La 12 pacienţi a fost necesar de efectuat o serie de investigaţii suplimentare pentru diferenţierea diagnosticului dintre adenom şi cancer de prostată.Summary. In article were analyzed the results of a multicenter screening study of the prostate pathology in men from 7 regions of R. of Moldova. According to the adopted protocol were examined 508 patients with a mean age of 63,3 ± 9,1 years. The structure of the identified pathologies (binign prostatic hyperplasia (BPH), prostate cancer (PC), prostatitis, the clinical features of BPH, the incidence of PC, the recommended treatment methods depending on the results of the screening were studied. The most frequent pathology was BPH - 425 cases or 83,7%, PC was diagnosed in 8 patients (1,6%) and chronic prostatitis in 62 (12,2%) patients. Most of the patients with BPH — 76,8% received indications for conservative treatment, 9,1% of patients received treatment for chronic prostatitis. Surgical treatment was indicated in 30 patients (5,9%) with BPH and specialized treatment for PC was indicated in 3 patients (0,6%). In 12 patients it was necessary to perform a number of additional investigations for differential diagnosis of adenoma and prostate cancer

The estimation of the peculiarities and the activity degree of the consisting inflammatory processes in the benign prostatic hyperplasia

Secţia Urologie, IMSP Spitalul Clinic Municipal “ Sf. Treime”, Catedra Morfopatologie, USMF „N. Testemiţanu”, Secţia Ştiinţifică Morfopatologie, IMSP Institutul de Cercetări Ştiinţifice în Domeniul Ocrotirii Sănătăţii Mamei şi Copilului, Catedra Urologie şi Nefrologie Chirurgicală, USMF „N. Testemiţanu”, Al V-lea Congres de Urologie, Dializă şi Transplant Renal din Republica Moldova cu participare internaţională (1-13 iunie 2011)Summary. The conducted study has the aim to estimate the histopathological peculiarities of the inflammatory processes, evaluated in prostatic nodular hyperplasia, the character and the activity of these processes in the area of nodular hyperplasia structures, and the border limit in the adenectomy. The results of the morphopathological study allowed detailed diagnosis of the prostatic hyperplasia. Severe modifications of inflammatory origin and considerable implications of the structural-architectonical components indicate concomitant persisting or coexisting of chronic or acute prostatitis. The establishment of the lesion character, activity degree of the inflammatory process, saving border limit in the surgical management regarding the residual cavity of cleavage and postoperative prognosis was the second aim of the study. It facilitates the choice of the best therapeutic and surgical approach. The character of the inflammatory processes coexisting with prostatic benign hyperplasia was evaluated. A clinical-morphological concept of inflammatory associations in prostate benign hyperplasia was formulated

СОВРЕМЕННЫЕ ПОДХОДЫ К ЛУЧЕВОМУ ЛЕЧЕНИЮ МЕТАСТАТИЧЕСКОГО ПОРАЖЕНИЯ ГОЛОВНОГО МОЗГА

The development of chemotherapy led to significant advances in cancer treatment, but its efficacy in treatment of brain metastases is insufficient. Fractionated whole brain irradiation has been the standard treatment for brain metastases, but provides limited local control and as a result, poor clinical results. Radiosurgery using "Gamma Knife" and "Cyber Knife" significantly changed the results of treatment of patients with metastatic brain lesions, which allowed to formulate new standards in the therapy of this group of patients. This review summarizes the current literature data on radiosurgical treatment of metastatic brain lesions with an emphasis on survival and quality of life, tumor response and potential combinations of treatments.Развитие  химиотерапии привело к существенному прогрессу  в терапии злокачественных опухолей, но ее эффек-тивность в отношении метастазов в головной  мозг (МГМ) является недостаточной. Фракционированное облучение всего головного мозга (ОВГМ) было стандартным методом  лечения  МГМ, но обеспечивает  ограниченный  локальный контроль и, как следствие,  неудовлетворительные  клинические результаты. Радиохирургия с использованием аппа-ратов «Гамма Нож», «Кибер Нож» существенно  изменила  результаты  лечения  пациентов с МГМ, что позволило сформулировать новые стандарты лечения этой группы больных.Настоящий обзор подводит итог текущих литературных данных радиохирургического  лечения МГМ с акцентом на выживаемость и качество жизни, ответа опухоли на лечение и потенциальных комбинациях методов лечения МГМ

Methodological approach for farm typology construction in terms of soil health – the EU case

Soil health is a significant problem in agriculture which demands a tailor-made approach. The study aims to develop a methodological approach for farm typology construction in terms of soil health. TUdi project, under which was made this study, aims to transform unsustainable management of soils in key cropping systems in Europe and China, developing an integrated platform of alternatives to reverse soil degradation. Thus, the focus is on small, medium, and large EU farms, which produce in the three key cropping systems - grassland, cereal-based rotation, and tree crops. It was applied principal component analysis based on which it was constructed four factors, related to soil health. The results from this analysis was used to feed up the cluster analysis together with other significant variables. The developed farm typology consists of four farm types. From practical point of view was introduced a methodology which allow to determine the type of each farm according the TUdi typology

Рецидивы метастазов в головном мозге после радиохирургического лечения. Существуют ли возможности стереотаксического лучевого лечения?

Цель исследования. Провести анализ результатов повторного радиохирургического (РХ) лечения пациентов с интракраниальными рецидивами метастазов в головной мозг (МГМ), после ранее проведенной РХ первично выявленных церебральных метастазов.Материалы и методы. Были изучены общая и безрецидивная выживаемость у 290 пациентов, получивших радиохирургическое лечение по поводу первично выявленных МГМ. Из них у 153 пациентов развились интракраниальные рецидивы, а 73 -проведено повторное радиохирургическое лечение по поводу новых (дистантных) метастазов.Результаты. Медиана общей выживаемости (ОВ) пациентов с дистантными метастазами (ДМ) составила 9,0 месяцев, а в группе без ДМ – 10,2 мес. (p = 0,3556). Статистически значимыми факторами прогноза развития ДМ (на момент проведения первой радиохирургии) являются: множественное (>3) метастатическое поражение головного мозга, плохой функциональный статус (индекс Карновского ≤70) и наличие меланомы как первоисточника метастазирования. Наличие ДМ, в целом по группе, не ухудшает общую выживаемость, а ОВ в группе пациентов с повторной РХ существенно выше (22,4 месяца,95% ДИ 14,8–38,6). Поэтому прогноз пациента с ДМ не является однозначно плохим, как это предполагалось ранее.Выводы. Повторная РХ дистантных метастазов увеличивает время жизни по сравнению с группой пациентов без локального лечения ДМ. Следовательно, повторная радиохирургия интракраниальных рецидивов приводит к улучшению выживаемости у части пациентов. Классификация интракраниальных рецидивов на основе ожидаемых результатов лечения в различных клинических ситуациях позволяет оптимизировать тактику лечения пациентов этой группы

Rhinitis in the geriatric population

The current geriatric population in the United States accounts for approximately 12% of the total population and is projected to reach nearly 20% (71.5 million people) by 2030[1]. With this expansion of the number of older adults, physicians will face the common complaint of rhinitis with increasing frequency. Nasal symptoms pose a significant burden on the health of older people and require attention to improve quality of life. Several mechanisms likely underlie the pathogenesis of rhinitis in these patients, including inflammatory conditions and the influence of aging on nasal physiology, with the potential for interaction between the two. Various treatments have been proposed to manage this condition; however, more work is needed to enhance our understanding of the pathophysiology of the various forms of geriatric rhinitis and to develop more effective therapies for this important patient population