194 research outputs found
The pedagogy of workers' self-management: Terror, therapy, and reform communism in Yugoslavia after the Tito-Stalin split
This is the final version of the article. Available from Oxford University Press via the DOI in this record.This article looks at the fields of psychoanalysis and psychiatry to read socialist Yugoslavia's complex international and political position. It argues that the history of postwar mental health professions in this country opens up a larger social and political story of liberalization and authoritarianism in socialist Eastern Europe. After 1948, the conflict with the Cominform, and split with the USSR, Yugoslavia went on to receive Western material help, as well as political support, and developed its own more liberal and internationally open brand of socialism, predicated on the ideas of workers' self-management and nonalignment. Yugoslav psychiatry and psychoanalysis became the most liberalized and Westernized professions in the region, but they also contributed to the operation of the violent "re-education" program at Goli Otok, the most authoritarian and repressive political project in Yugoslav history aimed at "re-educating" pro-Stalinists in the Yugoslav Communist Party. In this article, those two sides of the Yugoslav psychiatric profession will be demonstrated through the prism of self-management. First, the article discusses the application of psychotherapeutic techniques and self-management in the violent context of re-education camps for political prisoners. A similar combination of psychoanalysis and principles of self-management in "civilian" and Westernized child psychiatry is analysed in the second part. The article shows how these very similar notions and ideological principles could be used within the same sociopolitical framework and by the same profession but for radically different purposes
Franck-Condon factors and observed band strength distribution in the vibrational structure of the Ag_2 D-X band system
Potential curves for the X_1Σ_g^+ and D_1Σ_u^+ states of three diatomic silver isotopomers, ^(107)Ag_2, ^(107)Ag^(109)Ag and ^(109)Ag_2, were determined from the best available molecular constants by the Rydberg-Klein-Rees method. From these potentials, Franck-Condon factors and band-origin wave numbers were computed, and the reliability of the obtained values was verified by comparison with the observed band strength distribution and the measured band origin positions in a previously recorded D-X spectrum. The ratios of the Franck-Condon factors to those of corresponding isotopic bands were found to be very close to unity, revealing only a very small isotopic effect on the Franck Condon factors of Ag_2 D-X bands. The isotopic shifts of the calculated band origins agree well with previously measured displacements of band heads
Experimental analysis and FEM modelling of a cutting tool vibrations
Presented in this paper is a comparative analysis of vibrations, measured during machining process and modelled by FEM. Moreover, microscopic structure of chip cross section was analyzed in order to establish the frequency of lamellae generation and its influence on the total level of vibrations of the cutting tool. Based on the results thus obtained, a method was proposed which allows determination of tool wear degree through separation of reliable indicators from the high-frequency spectrum of the measured vibration signals. This investigation showed that the change of chip segmentation frequency significantly influences the output vibration signal within the high-frequency spectrum, and is a function of tool wear degree
Importance of polymorphisms in glucocorticoid receptor and adrenocorticotropic receptor genes in development of adrenal incidentalomas
UVOD: Glukokortikoidni hormoni (GC) ostvaruju svoje efekte vezivanjem za
glukokortikoidni receptor (GR). Adrenokortikotropni hormon (ACTH) reguliše sintezu
GC vezivanjem za ACTH receptor (ACTHR). Prisustvo polimorfizama u genu za GR
(BclI, N363S, ER22/23EK and A3669G) i promotoru ACTHR može uticati na efekte
glukokortikoida i predispoziciju za nastanak unilateralnih adrenalnih incidentaloma.
CILJ RADA: Utvrđivanje mogućeg uticaja funkcionalnih polimorfizama u genima za
GR i ACTHR na predispoziciju za nastanak adrenalnih incidentaloma i osetljivost na GC
i ispitivanje ekspresije GR u tumorskom, peritumorskom i zdravom adrenokortikalnom
tkivu.
METODE: U ispitivanje je bilo uključeno 112 pacijenata i 100 zdravih dobrovoljaca,
koji su podvrgnuti metaboličkom, genetičkom, biohemijskom i antropometrijskom
testiranju. DNK je dobijena iz leukocita periferne krvi. Prisustvo polimorfizama je
detektovano metodama PCR, RFLP i sekvenciranja DNK. Uzorci tkiva su analizirani
imunohistohemijskom metodom.
REZULTATI: Prisustvo dužeg C alela BclI (p<0.001) polimorfizma i kraćeg G alela
A3669G (p<0.001) polimorfizma GR gena su bili nezavisni prediktori adrenalnih
incidentaloma. Pacijenti sa prisutnim C alelom BclI su imali veće tumore (p=0.002), a oni
sa G alelom A3669G više vrednosti postdeksametazonskog kortizola (p=0.025).
Istovremeno prisustvo oba alela je koreliralo sa manjim obimom struka (p=0.002), a
višim baznim i postdeksametazonskog kortizolom (p=0.024). Smanjena ekspresija GRα i
GRβ izoformi zapažena je u tumorskom, a GRα u peritumorskom tkivu. Lokalizacija
GRβ je bila dominantno nukleusna.
ZAKLJUČAK: Prisustvo C alela BclI i G alela A3669G polimorfizmama gena za GR se
nalaze u vezi sa nastankom unilateralnih adrenalnim incidentalomima, a njihovo
zajedničko prisustvo dovodi do smanjene osetljivosti na GC. Stečena intraadenomatozna
glukokortikoidna rezistencija može da dovede do disregulacije produkcije kortizola i
rasta tumora u isto vreme, dok prirodna osetljivost na glukokortikoide najverovatnije
modifikuje ove efekte.INTRODUCTION: Glucocorticoid hormones (GCs) accomplish their effects through
binding to glucocorticoid receptor (GR). Adrenocorticotropic hormone (ACTH) regulates
synthesis of GCs through binding to ACTH receptor (ACTHR). Presence of common GR
gene (BclI, N363S, ER22/23EK and A3669G) and ACTHR promoter polymorphisms can
modulate GCs sensitivity.
OBJECTIVE: The aim of present study was to determine weather functional
polymorphisms in GR and ACTHR genes influence susceptibility for unilateral adrenal
incidentalomas and GC sensitivity, and to investigate GR expression in tumorous,
peritumorous and normal adrenocortical tissue samples.
METHODS: The study included 112 patients with adrenal incidentalomas and 100
population-matched controls. All subjects underwent metabolic, genetic, biochemical and
anthropometric testing. DNA was obtained from peripheral blood leucocytes. The
polymorphisms were detected using PCR, RFLP and DNA sequencing. Tissue samples
were studied by immunohistochemistry.
RESULTS: GR gene variant, C allele of BclI (p<0.001) and G allele of A3669G
(p<0.001) polymorphisms were independent predictors of adrenal incidentalomas.
Patients with present C allele had larger tumors (p=0.002), but those with G allele had
higher postdexamethasone serum cortisol (p=0.025). Both allele carriers had lesser waist
circumference (p=0.002), higher basal (p=0.024) and postdexamethasone cortisol
concentrations. In tumorous tissues GRα and GRβ isoforms had lower expression, but
only GRα in peritumorous tissue. Localization of GRβ was dominantly nuclear.
CONCLUSION: GR gene variants, larger C allele of BclI and minor 3669G allele are
associated with adrenal incidentalomas. Their concurrent presence in patients reduces GC
sensitivity. The acquired tumorous GC resistance probably promote dysregulated cortisol
production and tumor growth, but natural sensitivity to glucocorticoides maybe modifies
these effects
Optimalni model metode konačnih elemenata (MKE) konstrukcije strijele plovnog bagera
This paper is presentation of the development of advanced approach for modeling and structural analysis of jib structure which is usually part of waterway bucket dredgers. Object of analysis is a jib structure which will be reconstructed for the excavation of grain material from a river bed. Main goal of paper is to proof benefits of enough sophisticated i.e. “optimal” FEM model for structural analysis of this type of structures in comparison with simple, but not adequate models. Proper stress state is emphasized as primary, but not only condition. It is necessary to reach serviceability and durability state, as well as affordable financial construction circumstances.Rad je kratki prikaz razvitka naprednog pristupa u modeliranju i strukturnoj analizi konstrukcije strijele, koja je uobičajeni dio plovnih bagera. Predmet analize je konstrukcija strijele bagera vedričara rekonstruisanog za iskop šljunka sa dna vodotoka. Cilj rada je da dokaže prednosti dovoljno sofi sticiranog tj. “optimalnog” MKE modela za analizu ovog tipa konstrukcija u odnosu na jednostavne, ali neodgovarajuće modele. Odgovarajuće naponsko stanje je istaknuto kao primarni, ali ne i jedini uvjet za rabljenje bagera. Potrebno je osigurati i odgovarajuće stanje upotrebljivosti i trajnosti, kao i povoljne ekonomske uvjete izrade konstrukcije
Constraining free parameters of a color superconducting non-local Nambu-Jona-Lasinio model using Bayesian analysis of neutron stars mass and radius measurements
We provide a systematic study of hybrid neutron star equations of state (EoS)
consisting of a relativistic density functional for the hadronic phase and a
covariant nonlocal Nambu--Jona-Lasinio (nlNJL) model to describe the color
superconducting quark matter phase. Changing the values of the two free
parameters, the dimensionless vector and diquark coupling strengths
and results in a set of EoS with varying stiffness and deconfinement
onset. The favorable parameters are obtained from a systematic Bayesian
analysis for which the multi-messenger constraint on the neutron star radius at
M and the combined mass-radius constraint for PSR J0740+6620 from
NICER experiment are used as the constraints. Additionally, the transition from
hadronic matter to deconfined quark matter is constrained to occur above
nuclear saturation density. Hybrid stars modeled with these favorable
parameters are compatible with the NICER results for the radius of the highest
known mass neutron star, PSR J0740+6620. Three new observations interesting for
neutron star phenomenology are reported: 1) We show that the constant sound
speed (CSS) EoS provides an excellent fit to that of the nlNJL model which
implies the squared speed of sound at high densities to be about for the
optimized parameters; 2) we give a simple functional form for the mapping
between the parameter spaces of these two models valid for the whole range of
relevant chemical potentials and 3) we observe that the special point property
of hybrid EoS based on CSS quark matter generalizes to a set of lines
consisting of special points when two EoS parameters are varied instead of one.
A lower limit for the maximum mass of hybrid stars as a function of the vector
coupling strength is obtained.Comment: 18 pages, 14 figures, 2 tables; major revision of v1 with Bayesian
analysis, discussion of special points, new text, figures and references
adde
Franck–Condon factors and observed band strength distribution in the vibrational structure of the Ag2 D-X band system
TPotential curves for the X1Sg+ and D1Su+ states of three diatomic silver isotopomers, 107Ag2, 107Ag109Ag and 109Ag2, were determined from the best available molecular constants by the Rydberg–Klein–Rees method. From these potentials, Franck–Condon factors and band-origin wavenumbers were computed, and the reliability of the obtained values was verified by comparison with the observed band strength distribution and the measured band origin po¬sitions in a previously recorded D-X spectrum. The ratios of the Franck–Con¬don factors to those of corresponding isotopic bands were found to be very close to unity, revealing only a very small isotopic effect on the Franck–Condon factors of Ag2 D-X bands. The isotopic shifts of the calculated band origins agree well with previously measured displacements of band heads
Comparison of sequential and single extraction in order to estimate the environmental impact of metals from fly ash
The aim of this paper is to simulate leaching of metals from fly ash in different environmental conditions using ultrasound and microwave-assisted extraction techniques. Single-agent extraction and sequential extraction procedures were used to determine the levels of different metals leaching. The concentration of metals (Al, Fe, Mn, Cd, Co, Cr, Ni, Pb, Cu, As and Be) in fly ash extracts were measured by inductively coupled plasma-atomic emission spectrometry. Single-agent extractions of metals were conducted at sonication times of 10, 20, 30, 40 and 50 min. Single-agent extraction with deionized water was also performed by exposing samples to microwave radiation at temperature of 50 degrees C. The sequential extraction was conducted according to the BCR procedure which was modified and applied to study the partitioning of metals in coal fly ash. The microwave-assisted sequential extraction was performed at different extraction temperatures: 50, 100 and 150 degrees C. The partitioning of metals between the individual fractions was investigated and discussed. The efficiency of the extraction process for each step was examined. In addition, the results of the microwave-assisted sequential extraction are compared to the results obtained by standard ASTM method. The mobility of most elements contained in the fly ash is markedly pH sensitive
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