7 research outputs found

    Identification of chosen apoptotic (TIAR and TIA-1) markers expression in thyroid tissues from adolescents with immune and non-immune thyroid diseases.

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    The aim of this study was to estimate sodium iodide symporter (NIS) and thyroid peroxidase (TPO) expression in thyrocytes from patients with GD and no-toxic multinodular goitre (NTMG) in relationship with apoptotic (TIAR and TIA-1) markers. The investigation was performed on thyroid cells isolated from postoperation thyroid tissues from 15 patients aged 12-21 years old with GD and 15 cases aged 13-21 years old with NTMG. Detection of NIS and TPO was performed by immunohistochemistry. Analysis of apoptotic markers in thyroid tissues was performed using antibodies to TIAR and TIA-1 by Western Blot and immunohistochemistry. Identification of proapoptotic TIAR and TIA-1 molecules in the thyroid tissues revealed a higher expression of both proteins in patients with Graves' disease (+++; +, respectively) in comparison to patients with NTNG (+; 0). In addition, TIAR expression was detected in three bands [p50, p42, p38 (kDa)] and TIA-1 in two bands [p22, p17 (kDa)]. using Western Blot test in patients with thyroid autoimmune diseases. In patients with NTNG expression of both apoptotic proteins was lower and identified in single bands: 42 (kDa) for TIAR and 17 (kDa) for TIA-1. The analysis of expression of NIS and TPO in thyroid follicular cells was higher in patients with Graves' disease in compared to their detection in patients with NTMG. In addition, degree of thyroid antigen expression positive correlated with amount of proapoptotic markers (TIAR,

    The present value of a portfolio of assets with present values determined by trapezoidal ordered fuzzy numbers

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    We consider the obvious thesis that the present value of a portfolio is equal to the sum of the present values of its components. The main goal of this paper is the implementation of this thesis in the case when present values are determined by trapezoidal ordered fuzzy numbers. We apply the revised sum of ordered fuzzy numbers. The associativity of such a revised sum is investigated here. In addition, we show that the multiple revised sum of a finite sequence of trapezoidal ordered fuzzy numbers depends on the ordering of its summands. Without any obstacles, the results obtained can be generalized to the case of any ordered fuzzy numbers

    Electrochemical Reduction of Industrial Baths Used for Electropolishing of Stainless Steel

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    Long-term exploitation of industrial electropolishing baths may contribute to the emergence of surface defects and may limit the range of applicable current densities. Due to this, extending the time of use of industrial baths is a major challenge. The application of electrochemical reduction in the process of reduction industrial baths enabled to reduce its contamination and, as a result, to enhance the surface quality of electropolished samples of grade 304 stainless steel. The contamination influence of the electropolishing bath on such parameters of the electropolished samples as roughness, gloss, mass reduction, and corrosion resistance was compared. The conducted tests included reduction of the contaminated industrial bath with use of cathodic reduction and monitoring of bath contamination with use of emission spectrometry ICP-OES. Potentiodynamic tests in 0.5 M chlorine environment with the aim to determine the influence of electrochemical reduction of the plating bath on surface resistance demonstrated that the pitting corrosion resistance of samples electropolished in a bath after reduction was reduced by approximately 0.1 V in comparison with samples electropolished before reduction. The calculations conducted for 24 corrosion resistance measurements demonstrated that differences between the results were significant. Bath reduction leads to improved roughness and gloss, even by approximately 500 GU (gloss units). At the same time, mass reduction decreases even by 13% in comparison with the process conducted in the bath before reduction. This may have a positive influence by slowing down the bath contamination process and, as a result, it reduces negative environmental impact. Another argument that supports the reduction of industrial baths is slowing down the process of cathode contamination during the electropolishing process. In industrial conditions, this may extend the possibility to conduct the process without the need for cathode reduction or replacement
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