Correlation of Hepatitis C Antibody Levels in Gingival Crevicular Fluid and Saliva of Hepatitis C Seropositive Hemodialysis Patients

Search for hepatitis C virus (HCV) in body fluids other than blood is important when assessing possible nonparenteral routes of viral transmission. However, the role of oral fluids in HCV transmission remains controversial. Our aim was to compare the prevalence of HCV antibody (HCV Ab) levels in saliva, and gingival crevicular fluid (GCF) of HCV seropositive hemodialysis patients. Serum, saliva and GCF samples were collected from thirty-nine patients. Samples were analyzed for HCV Ab using the Ortho HCV 3.0 SAVe enzyme-linked immunosorbent assay (ELISA). HCH Ab levels in saliva and GCF of all HCV-seropositive patients were statistically compared. Reported here are the results of the study designed to determine the correlation between HCV-RNA positivity in serum and the detection of antibodies in GCF and saliva. One hundred percent (100%) of the 39 patients have antibodies to HCV in their serum, 15.4% have antibodies to HCV in GCF, and saliva found out. HCV Ab seropositivity in GCF and saliva was significantly correlated (kappa = 0.462; P < .001). This study supports the concept that GCF may be a significant source of HCV in saliva

Multiple unerupted mandibular permanent molar teeth: a case report

&lt;p&gt;The multiple impacted teeth at jaws are a rare condition that frequently associated with syndromes, metabolic disorders or trauma. A 48-year old male patient was referred to our clinic, with complaint of pain on right retromolar region while chewing. The patient had facial asymmetry and restricted mouth opening. Clinical and radiographic examination revealed the impaction of mandibular first, second and third molar and an abnormal condyle and coronoid process. All of the impacted teeth were extracted. Because the patient refused other treatment procedures no surgical intervention was performed for the asymmetry and restricted mouth opening. Six months clinic and radiographic follow up were satisfactory.&lt;/p&gt