241 research outputs found
Shell model description of Ge isotopes
A shell model study of the low energy region of the spectra in Ge isotopes
for is presented, analyzing the excitation energies,
quadrupole moments, values and occupation numbers. The theoretical
results have been compared with the available experimental data. The shell
model calculations have been performed employing three different effective
interactions and valence spaces.We have used two effective shell model
interactions, JUN45 and jj44b, for the valence space
without truncation. To include the proton subshell in valence space
we have employed the effective interaction due to Sorlin {\it et al.},
with Ca as a core and a truncation in the number of excited particles.Comment: 10 pages, 10 figures, Proc. of the XXXV Nuclear Physics Symposium,
January 3-6 2012, Cocoyoc, Morelos, Mexico. IOP Journal of Physics:
Conference Series (in press
Non-classicality of photon added coherent and thermal radiations
Production and analysis of non-Gaussian radiation fields has evinced a lot of
attention recently. Simplest way of generating such non-Gaussians is through
adding (subtracting) photons to Gaussian fields. Interestingly, when photons
are added to classical Gaussian fields, the resulting states exhibit {\em
non-classicality}. Two important classical Gaussian radiation fields are
coherent and thermal states. Here, we study the non-classical features of such
states when photons are added to them. Non-classicality of these states shows
up in the negativity of the Wigner function. We also work out the {\em
entanglement potential}, a recently proposed measure of non-classicality for
these states. Our analysis reveals that photon added coherent states are
non-classical for all seed beam intensities; their non-classicality increases
with the addition of more number of photons. Thermal state exhibits
non-classicality at all temperatures, when a photon is added; lower the
temperature, higher is their non-classicality.Comment: Version 2, minor revision; new references added, to appear in Eur.
Phys. J. D, 6 pages, 10 figure ps files, RevTe
Soluble urokinase plasminogen activator receptor (suPAR) levels predict damage accrual in patients with recent-onset systemic lupus erythematosus
© 2019 The Authors Objective: The soluble urokinase plasminogen activator receptor (suPAR) has potential as a prognosis and severity biomarker in several inflammatory and infectious diseases. In a previous cross-sectional study, suPAR levels were shown to reflect damage accrual in cases of systemic lupus erythematosus (SLE). Herein, we evaluated suPAR as a predictor of future organ damage in recent-onset SLE. Methods: Included were 344 patients from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort who met the 1997 American College of Rheumatology classification criteria with 5-years of follow-up data available. Baseline sera from patients and age- and sex-matched controls were assayed for suPAR. Organ damage was assessed annually using the SLICC/ACR damage index (SDI). Results: The levels of suPAR were higher in patients who accrued damage, particularly those with SDI≥2 at 5 years (N = 32, 46.8% increase, p = 0.004), as compared to patients without damage. Logistic regression analysis revealed a significant impact of suPAR on SDI outcome (SDI≥2; OR = 1.14; 95% CI 1.03–1.26), also after adjustment for confounding factors. In an optimized logistic regression to predict damage, suPAR persisted as a predictor, together with baseline disease activity (SLEDAI-2K), age, and non-Caucasian ethnicity (model AUC = 0.77). Dissecting SDI into organ systems revealed higher suPAR levels in patients who developed musculoskeletal damage (SDI≥1; p = 0.007). Conclusion: Prognostic biomarkers identify patients who are at risk of acquiring early damage and therefore need careful observation and targeted treatment strategies. Overall, suPAR constitutes an interesting biomarker for patient stratification and for identifying SLE patients who are at risk of acquiring organ damage during the first 5 years of disease
Vertical distribution of Atlantic bluefin tuna Thunnus thynnus and bonito Sarda sarda larvae is related to temperature preference
As part of the endeavor aiming at the domestication of Atlantic bluefin tuna (BFT; Thunnus thynnus), first sexual maturity in captivity was studied by documenting its occurrence and by characterizing the key hormones of the reproductive axis: follicle stimulating hormone (FSH) and luteinizing hormone (LH). The full length sequence encoding for the related hormone b-subunits, bftFSHb and bftLHb, were determined, revealing two bftFSHb mRNA variants, differing in their 50 untranslated region. A quantitative immuno-dot-blot assay to measure pituitary FSH content in BFT was developed and validated enabling, for the first time in this species, data sets for both LH and FSH to be compared. The expression and accumulation patterns of LH in the pituitary showed a steady increase of this hormone, concomitant with fish age, reaching higher levels in adult females compared to males of the same age class. Conversely, the pituitary FSH levels were elevated only in 2Y and adult fish. The pituitary FSH to LH ratio was consistently higher (>1) in immature than in maturing or pubertal fish, resembling the situation in mammals. Nevertheless, the results suggest that a rise in the LH storage level above a minimum threshold may be an indicator of the onset of puberty in BFT females. The higher pituitary LH levels in adult females over males may further support this notion. In contrast three year-old (3Y) males were pubertal while cognate females were still immature. However, it is not yet clear whether the advanced puberty in the 3Y males was a general feature typifying wild BFT populations or was induced by the culture conditions. Future studies testing the effects of captivity and hormonal treatments on precocious maturity may allow for improved handling of this species in a controlled environment which would lead to more cost-efficient farmingVersión del edito
Strange particle production in proton-proton collisions at TeV with ALICE at the LHC
The production of mesons containing strange quarks (K, ) and both
singly and doubly strange baryons (, Anti-, and
+Anti-) are measured at central rapidity in pp collisions at
= 0.9 TeV with the ALICE experiment at the LHC. The results are
obtained from the analysis of about 250 k minimum bias events recorded in 2009.
Measurements of yields (dN/dy) and transverse momentum spectra at central
rapidities for inelastic pp collisions are presented. For mesons, we report
yields () of 0.184 0.002 stat. 0.006 syst. for K and
0.021 0.004 stat. 0.003 syst. for . For baryons, we find
= 0.048 0.001 stat. 0.004 syst. for , 0.047
0.002 stat. 0.005 syst. for Anti- and 0.0101 0.0020 stat.
0.0009 syst. for +Anti-. The results are also compared with
predictions for identified particle spectra from QCD-inspired models and
provide a baseline for comparisons with both future pp measurements at higher
energies and heavy-ion collisions.Comment: 33 pages, 21 captioned figures, 10 tables, authors from page 28,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/387
Measuring the impact and costs of a universal group based parenting programme : protocol and implementation of a trial
Background
Sub-optimal parenting is a common risk factor for a wide range of negative health, social and educational outcomes. Most parenting programmes have been developed in the USA in the context of delinquency prevention for targeted or indicated groups and the main theoretical underpinning for these programmes is behaviour management. The Family Links Nurturing Programme (FLNP) focuses on family relationships as well as behaviour management and is offered on a universal basis. As a result it may be better placed to improve health and educational outcomes. Developed in the UK voluntary sector, FLNP is popular with practitioners, has impressed policy makers throughout the UK, has been found to be effective in before/after and qualitative studies, but lacks a randomised controlled trial (RCT) evidence base.
Methods/Design
A multi-centre, investigator blind, randomised controlled trial of the FLNP with a target sample of 288 south Wales families who have a child aged 2-4 yrs living in or near to Flying Start/Sure Start areas. Changes in parenting, parent child relations and parent and child wellbeing are assessed with validated measures immediately and at 6 months post intervention. Economic components include cost consequences and cost utility analyses based on parental ranking of states of quality of life. Attendance and completion rates and fidelity to the FLNP course delivery are assessed. A nested qualitative study will assess reasons for participation and non-participation and the perceived value of the programme to families. By the end of May 2010, 287 families have been recruited into the trial across four areas of south Wales. Recruitment has not met the planned timescales with barriers including professional anxiety about families entering the control arm of the trial, family concern about video and audio recording, programme facilitator concern about the recording of FLNP sessions for fidelity purposes and delays due to the new UK research governance procedures.
Discussion
Whilst there are strong theoretical arguments to support universal provision of parenting programmes, few universal programmes have been subjected to randomised controlled trials. In this paper we describe a RCT protocol with quantitative and qualitative outcome measures and an economic evaluation designed to provide clear evidence with regard to effectiveness and costs. We describe challenges implementing the protocol and how we are addressing these
Two-pion Bose-Einstein correlations in central Pb-Pb collisions at = 2.76 TeV
The first measurement of two-pion Bose-Einstein correlations in central Pb-Pb
collisions at TeV at the Large Hadron Collider is
presented. We observe a growing trend with energy now not only for the
longitudinal and the outward but also for the sideward pion source radius. The
pion homogeneity volume and the decoupling time are significantly larger than
those measured at RHIC.Comment: 17 pages, 5 captioned figures, 1 table, authors from page 12,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/388
マターナル・アタッチメントの個人差-養育行動及び子どものアタッチメント行動との関連について-
本研究の目的は,①生後18ヵ月から生後36ヵ月におけるマターナル・アタッチメントの発達的変化を検討すること,②生後36ヵ月のマターナル・アタッチメントの個人差と母親の養育行動(教授行動,感受性)及びアタッチメントQ分類法によって評定された子どものアタッチメント行動との関連を検討することであった。妊娠期から生後36ヵ月まで追跡した15組の母子を対象に調査が実施された。その結果,以下の点が明らかとなった。①生後18ヵ月から生後36ヵ月にかけて,マターナル・アタッチメント得点は有意に低下した。また,生後18ヵ月と生後36ヵ月のマターナル・アタッチメント得点の間に正相関が認められた。②マターナル・アタッチメント得点の高い母親ほど,感受性が高く,間接的な教授をする傾向があり,そのような母親の子どもほど安定性得点が高い傾向にあった。以上の結果から,マターナル・アタッチメントが養育行動や子どものアタッチメント行動にとって重要となることが示唆された。Developmental changes in maternal attachment from 18 to 36 months of age were examined. The study also investigated the relationship between individual differences in maternal attachment, parental behaviors such as mother's teaching and maternal sensitivity, as well as infant-mother attachment using the Attachment Q-sort. Mother-child pairs (n = 15) participated in a longitudinal study from pregnancy to 36 months of age. The results were as follows. (1) Maternal attachment scores decreased significantly from 18 to 36 months of age. Moreover, there was a positive correlation between maternal attachment at 18 months and at 36 months. (2) Mothers with higher maternal attachment scores tended to have higher maternal sensitivity scores and used indirect teaching methods more often. The infants of these mothers tended to have higher Q-sort security scores. These results suggest that maternal attachment is important for parental behavior and infant-mother attachment.報告Report
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