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學位論文(碩士)--亞洲大學敎 大學院 :産業工學科,2001Maste

Influence of Miniplate Shapes as Skeletal Anchorage for Application of Orthopedic Force: A Three-Dimensional Finite Element Analysis

Purpose: This study was performed to evaluate the stress distribution in the bone and the displacement distribution of the miniscrew under orthopedic force with two different types of miniplate design as skeletal anchorage for orthopedic treatment. Materials and methods: Finite element models were made for 6-hole miniplate (0.8mm in thickness), which were designed in two different shapes-one is curvilinear shaped (C plate, Jeil Medical Co., Korea) and another, Y shaped (Y plate), fixed with 3 pieces of miniscrew 2mm-diameter and 6mm-long respectively. A traction force of 4 N was applied in 0º, 30ºand 60ºto imaginary axis connecting two unfixed distalmost holes of the miniplate. Results: The maximum von Mises stress in the bone was much greater in the cortical portion rather than in the cancellous portion. C plate showed greater maximum von Mises stress in the cortical bone than Y plate. The maximum displacement of the miniscrew was greater in C plate than Y plate. The more increased the angle of the applied orthopedic force, the greater maximum von Mises stress in the bone and maximum displacement of the miniscrew. It was observed that in C plate, the von Mises stress in the bone and displacement of the miniscrew were distributed around the distalmost screw-fixed area. Conclusions: The results suggest that Y plate should have the advantage over C plate and in the placement of the miniplate, its imaginary axis should be placed as parallel as possible to the direction of orthopedic force to obtain its primary stability.이 논문은 2006년도 강릉대학교 치과병원 협동임상연구비 지원을 받았음

COMPOSITION FOR INDUCING THE DIFFERENTIATION INTO M2 MACROPHAGE COMPRISING MESOPORUS SILICA NANOPATICLES AND CYTOKINE CONTAINED THEREIN

본 발명의 사이토카인이 담지된 다공성 실리카 나노입자를 포함하는 M2 대식세포로의 분화유도용 조성물은, 사이토카인을 생체 내로 전달하여 단핵구, 대식세포 등이 M2 대식세포로 분화하는 것을 유도함으로써, 과도한 면역 반응을 조절하여 효과적인 면역반응이 일어날 수 있도록 한다

COMPOSITION FOR ANTI-INFLAMMATION COMPRISING MESOPORUS SILICA NANOPARTICLES AND CYTOKINE CONTAINED THEREIN

본 발명의 사이토카인이 담지된 다공성 실리카 나노입자를 포함하는 염증억제용 조성물은 사이토카인을 생체 내로 전달하여 염증 반응이 보다 빠르고 효과적으로 억제될 수 있도록 한다