The Cold War Culture as a Ritual and the Aspirations of North Korean Migrants

본 연구는 국가권력에 의한 냉전의례와 평화지향적 의례의 불균형을 성찰하면서 통일담론의 한계를 지적하고, 그러한 의례로서의 냉전문화가 북한이탈주민들의 한국사회 적응 과정에서 어떠한 유형들로 재생산되거나 협상되는지 민족지적으로 중층기술한다. 냉전을 의례로서 고찰함으로써, 한국 근대사의 조작된 위험을 상징적으로 보여주는 냉전문화가 국가 차원에서는 어떻게 재생산되는지, 평화적 통일이라는 헌법 정신은 왜 점차 외면되고 있는지에 대한 분석을 현실적으로 하고자 평화적 의례와의 불균형성에 대해 심층적으로 논의한다. 나아가 북한이탈주민들이 기독교와 만나고 종교적 회심을 경험하는 과정에서 어떻게 냉전의례가 재생산되고 변형되는지에 대해서 민족지 기술을 시도한다. 궁극적으로 본 논고는, 미래지향적 열망인 통일감수성, 관용과 환대의 가치를 로컬공동체 차원에서 실현하는 과정과 소통 중심의 플랫폼 구상을 제안한다. This study points out the limitations of unification discourse by reflecting on the imbalance between Cold War rituals and peace-oriented rituals by state power, and demonstrates the types of cold war culture reproduced or negotiated in the process of North Korean defectors adaptation to Korean society. By considering the Cold War as a ritual, this paper discusses in-depth the imbalance with peaceful rituals to analyze how the Cold War culture symbolizes the fabricated dangers of modern Korean history is reproduced at the national level and why the constitutional spirit of peaceful unification is gradually being neglected. Furthermore, this ethnography describes what types of Cold War rituals are reproduced and transformed in the process of North Korean defectors encountering with Christianity and experiencing religious conversion. Ultimately, this paper proposes the process of realizing the values of unification sensitivity, tolerance, and hospitality, which are future-oriented aspirations, and a platform initiative centered on intercultural dialogues at the local community level

저산소증 상태에서 알츠하이머병 사이브리드 세포의 HIF-1α와 BACE 발현에 대한 스타틴의 효과

학위논문 (석사)-- 서울대학교 대학원 : 의학과 뇌신경과학 전공, 2013. 2. 한문구.Background: Alzheimers disease (AD) is a progressive neurodegenerative disorder affecting memory function and higher cognitive function. Vascular risk factors have an established association with AD, and brain ischemia facilitates the pathogenesis of AD by accumulating beta amyloid (Aβ). Hypoxia increases the expression of β-site amyloid precursor protein cleaving enzyme (BACE) through overexpression of hypoxia inducible factor 1α (HIF-1α), resulting in accumulation of Aβ. Statins (HMG-CoA reductase inhibitor) have protective effects against hypoxia, and long-term statin treatment is known to decrease the risk of developing AD. Methods and Results: In this study, we used mitochondrial transgenic neuronal cell (cybrid) models to investigate the changes of intracellular HIF-1α and BACE levels with administration of statins under hypoxia. Sporadic AD (SAD) cybrids and age-matched control (CTL) cybrids were incubated under hypoxia (93% N2/5% CO2/2% air), and then 1 μM or 10 μM simvastatin was administrated. Intracellular HIF-1α and BACE levels were measured using Western-blot analysis. Under hypoxia, CTL and SAD cybrids showed reduced viability over time, and the intracellular expression of HIF-1α and BACE was increased. After administration of 1 μM simvastatin, the intracellular levels of HIF-1α and BACE were decreased in SAD cybrids. With 10 μM simvastatin, the intracellular expression of HIF-1α and BACE was increased in both SAD and CTL cybrids. Conclusion: A low-dose statin reduces the expression of HIF-1α and BACE under hypoxia in SAD cybrids. In contrast, a high-dose statin aggravates the expression of HIF-1α and BACE in both SAD and CTL cybrids. These results suggest that low-dose statins are more beneficial than high-dose statins in the prevention of Aβ production.Abstract in English - i List of Figures - iii Contents - iv Introduction -1 Materials and Methods - 3 Results - 6 Discussion - 14 References - 17 Abstract in Korean - 21Maste