22 research outputs found
Similarities in the Structure of Human Resource System and Cultural Values among three Korean Terrestrial Broadcasters
This study tried to examine how three terrestrial broadcasters were institutionalized by inter-organizational imitations. More specifically, this paper focused on similarities in the structure of human resource system and cultural values among three Korean terrestrial broadcasters. In other words, this study raised questions about why and how three broadcasters including KBS, MBC and SBS were different from each other in terms of their human resource system and members' cultural values. Using both literature review and survey data, this research has examined differences or similarities of human resource system among three terrestrial broadcasters since 2000. The results showed that three terrestrial broadcasters were different each other in terms of human resource system. Each broadcaster had own distinct characteristics for developing human resource system. Although MBC has experienced high degree of fluctuations in human resource system, SBS was relatively stable. In addition, there were a lot of arguments about the adoption of the team-based organization in KBS. Also the results of discriminant analysis showed that members or program production staffs in three broadcasters had a slightly different values. More specifically, members' values in public broadcasters including KBS and MBC were significantly different from members in private broadcaster such as SBS
์ค๋ฆฌ์ฝ ์ํ๋ํธ ์ฃผ๋ณ์ ์ฌ์ ํ ์๋ฐฉ์ ์ํ ํธ๋ฆฌ์์๋๋ก ์ ๊ตญ์์ ์ ์ด ์ ๋ฌ
ํ์๋
ผ๋ฌธ (์์ฌ)-- ์์ธ๋ํ๊ต ๋ํ์ : ๊ณต๊ณผ๋ํ ํ๋๊ณผ์ ๋ฐ์ด์ค์์ง๋์ด๋ง์ ๊ณต, 2018. 2. ์ต์๋น.I propose silicone implants capable of the local, controlled release of a glucocorticoid drug, triamcinolone acetonide (TA), for the prevention of fibrosis. The shells of these silicone implants were coated with two different loading amounts of TA, which could release the drug in a sustained manner for 12 weeks. The drug-loaded implants were inserted into the subcutaneous space in living rats, and the tissues were biopsied at scheduled times during 12 weeks. For the drug-coated implants, the capsule thickness and collagen density decreased compared with those of the non-coated implant. Because of the effect of TA, inflammation and the expression of pro-inflammatory cytokines, such as TNF-ฮฑ and IL-1ฮฒ, were downregulated, thereby decreasing the number of monocytes during acute inflammation. This effect in turn decreased the number of macrophages at the later stage of inflammation, leading to the expression of less TGF-ฮฒ and consequently fewer fibroblasts and myofibroblasts. Notably, with an appropriate dose of TA, skin and muscle atrophy, major side effects of TA, could be avoided while still effectively reducing fibrosis. Therefore, I conclude that the local, sustained release of an appropriate dose of a glucocorticoid drug can be a promising strategy for safely preventing fibrosis around silicone implants.1. Introduction 1
1.1 Background knowledge 1
1.2 Strategy 2
2. Materials and Methods 4
2.1 Materials 4
2.2 Preparation of silicone implant samples 5
2.3 Characterization 7
2.4 In vitro drug release experiments 7
2.5 In vivo animal study 8
2.6 Staining 9
2.7 Stained image analysis 10
2.8 Statistical analysis 12
3. Results 13
3.1 Implant characterization 13
3.2 Anti-fibrotic effects 17
3.3 Inflammation 20
3.4 Fibrotic factors 26
3.5 Drug side effects 30
4. Discussion 33
5. Conclusion 36
6. References 37
๊ตญ๋ฌธ์ด๋ก 42Maste
Diversity and the Degree of Concentration of the Media Markets in Korea
๋ค์์ฑ์ ์ปค๋ฎค๋์ผ์ด์
์ ์ฑ
์ ๊ธฐ๋ณธ ์์น์ผ๋ก ๋ฏธ๋์ด์ ๊ณต์ต์ฑ์ ๊ตฌํ์ด๋ ์ฐจ์์์๋ ํต์ฌ์ ์ธ ๊ฐ๋
์ผ๋ก ์ธ์๋์ด ์๋ค. ๊ตญ๋ด ๋ฏธ๋์ด ์์ฅ์ ๋ค์์ฑ์ ํ์ํ๊ธฐ ์ํ์ฌ ๋ณธ ์ฐ๊ตฌ๋ ๋ฏธ๋์ด ์ฌ์
์ ๋งค์ถ ๊ท๋ชจ๋ฅผ ์ค์ฌ์ผ๋ก ๋ฏธ๋์ด ์์ฅ ๋ด๋ถ ๋ฐ ๋ฏธ๋์ด ๊ฐ ์์ฅ์์์ ์์ ์ฌ์
์์ ์์ฅ์ง์ค๋๋ฅผ ์ธก์ ํ ์ ์๋ CR(Concentration Ratios)์ ์ด์ฉํด ์์ฅ ์ง์ค๋๋ฅผ ์ถ์ ํ๋ค. ์ฃผ์ ๋ถ์ ๊ฒฐ๊ณผ๋ ๋ค์๊ณผ ๊ฐ๋ค. ์ฒซ์งธ ์ ๋ฌธ์ด๋ ์ง์ํ ๋ฐฉ์ก์์ฅ์ ๊ฐ๋ณ์ ์ผ๋ก ํ๊ฐํด ๋ณผ ๋ ์ ์ฒด์ ์ผ๋ก ์์ฅ์ง์ค๋๊ฐ ์ํ๋๊ณ ์์์๋ ๋ถ๊ตฌํ๊ณ ์์ ์ฌ์
์์ ์ํ ์์ฅ์ง์ค๋๋ ํฐ ํธ์ผ๋ก ๋ํ๋๊ณ ์๋ค. ๋์งธ, ์ ๋ฌธ ๋ฐ ๋ฐฉ์ก ํตํฉ ์์ฅ์ ๊ฒฝ์ฐ ์ ๋ฌธ๊ณผ ๋ฐฉ์ก ์์ฅ ๋ด ์์ ์ฌ์
์์ ์์ฅ์ง์ค๋๋ ๋ถ์๊ธฐ๊ฐ ์ค ์ ์ฐจ ๊ฐ์ํ๊ณ ์๋ ๊ฒ์ ํ์ธํ ์ ์๋ค. ์์ 3๊ฐ ์ฌ์
์ ์์ฅ์ง์ค๋๋ 2006๋
๊น์ง 4.7% ๊ฐ์ํ๊ณ , ์์ 5๊ฐ ์ฌ์
์ ์์ฅ์ ์ ์จ์ ์๋งํ๊ฒ ๊ฐ์ํ์ฌ 2003๋
๋ถํฐ 2006๋
๊น์ง 8.3% ์ค์ด๋ค์๋ค. ์
์งธ, ์ ๋ฌธ์ ํฌํจํด ๋ฐฉ์ก, ์ธํฐ๋ท ์์ฅ๊น์ง ํตํฉํ ์์ฅ์ง์ค๋๋ฅผ ์ดํด๋ณด๋ฉด ์์ 5๊ฐ ์ฌ์
์๊ฐ ์ฐจ์งํ๋ ๋น์ค์ด 32.5%๋ก ๋ํ๋ฌ๋ค. ์ด๋ ํตํฉ๋ ๋ฏธ๋์ด ์์ฅ์ด ๋ถ์ฐ๋ ๊ตฌ์กฐ๋ฅผ ๊ฐ๊ณ ์๋ค๋ ๊ฒ์ ๋ํ๋ธ๋ค. ๊ทธ๋ฌ๋ ์์ ๊ตฌ์กฐ ํตํฉ ์์๋ ์ด์ ๊ฐ์ ๊ตฌ์กฐ์ ํน์ฑ์ด ๋ณํ๋ ๊ฒ์ด๋ค. ์์ผ๋ก ๊ตญ๋ด ๋ฏธ๋์ด ์์ฅ์์ ๋ํ๋๋ ๋ค์์ฑ ์ฐจ์์ ๋ณด๋ค ๊ตฌ์ฒด์ ์ผ๋ก ๋ถ์ํ๊ธฐ ์ํด์๋ ๊ณต๊ธ ์ฐจ์์์ ์์ ๊ตฌ์กฐ์ ์์ฅ์ง์ค๋ ๋ฐฉ์์ ๋์์ ๊ฒํ ํ๋ ํํธ ์ด์ฉ์ ์ธก๋ฉด์์์ ์ด์ฉ ์ง์ค๋ ์ถ์ธ๋ฅผ ํตํฉ์ ์ผ๋ก ์ดํด๋ณด์์ผ ํ ๊ฒ์ด๋ค