16 research outputs found

    ์ค‘ํ˜• ์„์œ ํ™”ํ•™์ œํ’ˆ ์šด๋ฐ˜์„ ์˜ ์ถ”์ง„์ถ•๊ณ„ ์•ˆ์ •์„ฑ ํ‰๊ฐ€์— ๊ด€ํ•œ ์—ฐ๊ตฌ

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    As the ship has high output and large size with the development of shipbuilding and steel technologies, the shaft stiffness increases, but it is the situation that the hull is deformed much more easily than before due to using high-strength steel plate. Therefore, deep experience and high attention of the designer are required as the propeller shaft cannot endure the reaction force change coming from the deformation of the hull, if the calculation of shaft alignment is done without considering the deformation of the hull. It can be said that the other area that is very closely connected with shaft alignment is the lateral vibration of propulsion shaft system. So, it should be considered in the safety assessment of shafting. It is better that the distance between centers of supporting bearings of the shaft system is longer in terms of shaft system alignment, but in terms of lateral vibration, the natural frequency becomes lower, so thereโ€™s a chance that resonance occurs in the range of engine operating speed. The research related to lateral vibration still remains as a problem to be solved due to unclear elements such as supporting bearingโ€™s stiffness in shaft system, oil filmโ€™s stiffness, propellerโ€™s exciting force, etc. Until now, it only ensures whether thereโ€™s a sufficient margin to avoid the natural frequency of 1st order propeller blades to be within ยฑ20% of the engine nominal speed in Classification Society, international standards, etc. Therefore, when considering such a situation, it is necessary to verify the calculation result of the natural frequency in the lateral vibration with the actual measurement. In the shaft system of a ship, the increase of local load in the stern tube bearing which supports a propeller shaft occurs prominently due to the influence of the propeller weight at the shaft end, similar to the case of the cantilever beam. Especially, the after stern tube bearing is likely to have a concentrated load in the bottom of aft side while the forward stern tube bearing does on the bottom of forward side. While such magnitude and distribution of local load are determined by the relative inclination angle between the shaft and bearing, the bottom of aft stern tube bearing is most affected among them. Such local load can deflect significantly toward the aft end of aft stern tube bearing in case that the shaft sags down, when the eccentric thrust force acts downward due to the propeller force in the hydrodynamic transient status. Case studies by some authors have presented the real-time dynamic behavior analysis of the shaft system in going-straight and turning by using the telemetry system. While the impact analysis of the shaft system in going-straight and turning of ship was carried out by domestic researchers recently, it was difficult to find the case which analyzed real-time dynamic behavior so far, so that it was considered meaningful to review the shaft behaviorโ€™s impact on the shaft system through this study. 50,000 DWT oil/chemical tanker is a type of ship emerging recently as a highly efficient eco-friendly ship and it lowered the engine speed by applying de-rating technology. It reduced fuel consumption significantly compared to similar ships and its feature is to maximize propulsion efficiency through applying the propeller of increased diameter. Therefore, some negative changes in terms of shaft alignment should be compared to similar ships, as the change in aft structure and increased weight of the propeller affect the deformation of the hull. Also, as the forward stern tube bearing is skipped, the natural frequency of lateral vibration becomes lower, so that the possibility of resonance in the operating speed range is expected to be slightly increased. After a review of previous researches, it is considered that thereโ€™s no comprehensive case study reported yet, which is related to the hull deformation, the lateral vibration and acceleration of the vessel and the shaft behavior in going-straight for 50,000 DWT oil/chemical tanker. Therefore, a theoretical review and analysis of measured data were performed in this study by using finite element analysis, strain gage method and reverse calculation method. And then the results are reported as follows after reviewing in detail the stability of the propeller shaft system of the target vessel. The finite element analysis result expects that the shaft is placed right down compared to the design value when it moves from light loading to full loading due to the hull deformation, and the reaction force of each bearing satisfying allowable values even under deformation. Also, the effect of hull deformation acts as a little positive factor increasing stability of the shaft system by relieving the relative angle of inclination of the aft stern tube bearing. While the hull deformation which is analyzed by using the strain gage method, is expected -2mm from the intermediate shaft bearing and about -4mm from the main engine bearing and it is a little bigger compared to the existing 47,000 DWT class, the increased weight of the propeller and main engine and the aft change due to the increase in propeller diameter are considered as main causes. The reaction force of the bearing supporting shaft system met allowable value like in the finite element analysis result, also in the full deformation and the cross validation result of bearing force obtained by the strain gage method, jack up method, and the shaft alignment program showed good correlations in most conditions so that the reliability of the analysis was able to be confirmed. The calculation result of lateral vibrationโ€™s natural frequency showed that resonant revolution speed was located in the area of more than 163.8% compared to MCR, so that it was above the limit value(ยฑ20%) and it was confirmed that there was no notable resonance point also in measurement analysis results. In case of 1st order component of lateral vibration, it showed the constant response of bending stress value regardless of rpm generally, it was considered because of run-out value. Furthermore, the measured bending stress was only 10% level of the provided measurement result, so that a negative influence by the lateral vibration was not expected to occur. The review result of the trajectory during the full laden draft operation showed that slight partial friction phenomenon was estimated with 25% of engine load in strain gage position #7. Therefore, it would be necessary to be careful on the long-time operation at 25% engine load to ensure the stability of shaft. strain gage position #5, it was considered acceptable phenomenon which could occur due to different anisotropy in vertical and horizontal stiffness in the intermediate shaft bearing. And while the hit and bounce friction phenomena was suspected at NCR condition (83 rpm) and it was expected to be stabilized after running-in operation. However, periodical monitoring was required to be continued through the shaft open-up survey when docking. Knowing the fact that the shaft direction in strain gage position #7 which was installed at the closest to propeller, moved toward left down direction with increasing engine load at both conditions regarding the shaft behavior. It was determined that the shaft direction in propeller location moved to the right upper direction which was the opposite to the moving direction of the strain gage installed location, and its effectiveness could be confirmed based on the previous study results obtained with direct measurements. Although the method above couldnโ€™t determine the exact displacement component at the center of shaft, it could provide the moving directionโ€™s pattern of propeller shaft by the engine load during operation, so that it was confirmed that it was significant and practical as an alternative method to the direct measurement one in the position of the propeller. Also, the propeller force during going-straight acted as a force lifting the shaft from the aft stern tube bearing and it reduced the possibility of damage to the aft stern tube bearing. Therefore, it was considered to contribute to improve the reliability of the shaft system. If the results obtained in this study are applied to similar type of ships for the shaft alignment and lateral vibration calculation, it is considered that it will help ensure the stability of the shaft system and prevent damages not only in quasi-static but also in dynamic conditions.๋ชฉ ์ฐจ ์ œ 1 ์žฅ ์„œ ๋ก  1 1.1 ์—ฐ๊ตฌ์˜ ๋ฐฐ๊ฒฝ 1 1.2 ์„ ํ–‰์—ฐ๊ตฌ(Literature survey) 3 1.2.1 ์ถ•๊ณ„์ •๋ ฌ 4 1.2.2 ์ถ•๊ณ„ ํšก์ง„๋™ 7 1.2.3 ์ถ•์˜ ๊ฑฐ๋™ ๋ถ„์„ 8 1.3 ์—ฐ๊ตฌ์˜ ๋ชฉ์  9 1.4 ์—ฐ๊ตฌ์˜ ๋‚ด์šฉ ๋ฐ ๊ตฌ์„ฑ 10 ์ œ 2 ์žฅ ์œ ํ•œ์š”์†Œ๋ฒ•์— ์˜ํ•œ ์ถ•๊ณ„์ •๋ ฌ ๊ณ„์‚ฐ ์ด๋ก  13 2.1 ๊ธฐ๋ณธ์‹์˜ ์œ ๋„ 13 2.1.1 ํšกํ•˜์ค‘๊ณผ ๋ชจ๋ฉ˜ํŠธ ํ•˜์ค‘์„ ๋ฐ›๋Š” ๋ถ€๋“ฑ ๋‹จ๋ฉด๋ณด์˜ ์ ˆ์  ๋ฐฉ์ •์‹ 13 2.1.2 ํšกํ•˜์ค‘๊ณผ ๋ชจ๋ฉ˜ํŠธ ํ•˜์ค‘์„ ๋ฐ›๋Š” ๋ณด์˜ ๊ฐ•์„ฑ ๋งคํŠธ๋ฆญ์Šค 16 2.2 ํšกํ•˜์ค‘๊ณผ ๋ชจ๋ฉ˜ํŠธ ํ•˜์ค‘์„ ๋ฐ›๋Š” ๋ถ€๋“ฑ ๋‹จ๋ฉด๋ณด ์ ˆ์ ๋ฐฉ์ •์‹์˜ ํ•ด๋ฒ• 18 2.2.1 ์ ˆ์ ๋ฐฉ์ •์‹์˜ ํ•ด๋ฒ• 18 2.2.2 ์ง€์ ์˜ ์ฒ˜๋ฆฌ 18 2.3 ๋ฐ˜๋ ฅ ์˜ํ–ฅ๊ณ„์ˆ˜์˜ ๊ณ„์‚ฐ 20 ์ œ 3 ์žฅ ์ถ•๊ณ„ ํšก์ง„๋™์˜ ์ด๋ก ์  ํ•ด์„ ๋ฐฉ๋ฒ• 23 3.1 ํšก์ง„๋™์˜ ๊ทผ์‚ฌ๊ณ„์‚ฐ๋ฒ• 23 3.1.1 Panagopulos์˜ ์‹ 23 3.1.2 ์ˆ˜์ • Panagopulos์˜ ์‹ 26 3.1.3 Jasper์˜ ์‹ 27 3.1.4 Jasper-Rayleigh์˜ ์‹ 33 3.2 ํšก์ง„๋™์˜ ์ •๋ฐ€ ๊ณ„์‚ฐ๋ฒ• 36 3.2.1 ๊ฐ•์„ฑ ๋งคํŠธ๋ฆญ์Šค๋ฅผ ์ด์šฉํ•œ ์ง„๋™๋ฐฉ์ •์‹์˜ ์œ ๋„ 37 3.2.2 ์ง„๋™๋ฐฉ์ •์‹์˜ ํ•ด๋ฒ• 40 ์ œ 4 ์žฅ ์ถ•๊ณ„ ๋ฒ ์–ด๋ง ๋ฐ˜๋ ฅ ์ธก์ •๋ฒ• 43 4.1 ์žญ์—…๋ฒ• 43 4.1.1 ์ฃผ๊ธฐ๊ด€ ์ตœํ›„๋ถ€ ๋ฒ ์–ด๋ง ์ธก์ • ๋ฐฉ๋ฒ• 47 4.1.2 ์ฃผ๊ธฐ๊ด€ ๋ฒ ์–ด๋ง ์ธก์ • ๋ฐฉ๋ฒ•(์ตœํ›„๋ถ€ ๋ฒ ์–ด๋ง ์™ธ) 49 4.1.3 ์„ ๋ฏธ๊ด€ ์„ ์ˆ˜๋ฒ ์–ด๋ง๊ณผ ์ค‘๊ฐ„์ถ• ๋ฒ ์–ด๋ง์˜ ์ธก์ • ๋ฐฉ๋ฒ• 52 4.1.4 ์žญ์—…๋ฒ•์„ ์ด์šฉํ•œ ๋ฒ ์–ด๋ง ์ง€์ง€ํ•˜์ค‘ ๊ณ„์‚ฐ ๋ฐฉ๋ฒ• 53 4.1.5 ์žญ์—…๋ฒ•์„ ์ด์šฉํ•œ ์ถ• ๋ถˆ๊ท ํ˜•(run-out)๋Ÿ‰ ๊ณ„์‚ฐ ๋ฐฉ๋ฒ• 55 4.2 ์ŠคํŠธ๋ ˆ์ธ ๊ฒŒ์ด์ง€๋ฒ• 55 4.2.1 ์ถ•๊ณ„ ๊ตฝํž˜๋ชจ๋ฉ˜ํŠธ ์‚ฐ์ถœ ๋ฐฉ๋ฒ• 60 4.2.2 ์ŠคํŠธ๋ ˆ์ธ ๊ฒŒ์ด์ง€๋ฒ•์„ ์ด์šฉํ•œ ๋ฒ ์–ด๋ง ์ง€์ง€ํ•˜์ค‘ ๊ณ„์‚ฐ ๋ฐฉ๋ฒ• 64 4.2.3 ์ŠคํŠธ๋ ˆ์ธ ๊ฒŒ์ด์ง€๋ฒ•์„ ์ด์šฉํ•œ ์ถ• ๋ถˆ๊ท ํ˜•(run-out)๋Ÿ‰ ๊ณ„์‚ฐ๋ฐฉ๋ฒ• 67 ์ œ 5 ์žฅ ์„ ์ฒด ๋ณ€ํ˜•์„ ๊ณ ๋ คํ•œ ์ถ”์ง„์ถ•๊ณ„ ์•ˆ์ •์„ฑ ํ‰๊ฐ€ 69 5.1 ์„ ์ฒด ๋ณ€ํ˜•์„ ๊ณ ๋ คํ•œ ์ถ•๊ณ„์ •๋ ฌ ํ•ด์„ ๋ฐฉ๋ฒ• 69 5.2 ํ•ด์„ ๊ฒฐ๊ณผ ๋ฐ ๊ณ ์ฐฐ 78 5.3 ์†Œ๊ฒฐ๋ก  89 ์ œ 6 ์žฅ ๊ณ„์ธก์น˜ ์—ญ๋ถ„์„์„ ํ†ตํ•œ ์ถ”์ง„์ถ•๊ณ„ ์•ˆ์ •์„ฑ ํ‰๊ฐ€ 91 6.1 ๊ณ„์ธก ๋ฐ ๋ฐ์ดํ„ฐ ๋ถ„์„ ๋ฐฉ๋ฒ• 91 6.2 ์„ ์ฒด ๋ณ€ํ˜•๋Ÿ‰ ์˜ˆ์ธก ๋ฐ ๋ฒ ์–ด๋ง ๋ฐ˜๋ ฅ ๊ณ„์‚ฐ ๊ฒฐ๊ณผ 96 6.3 ์†Œ๊ฒฐ๋ก  104 ์ œ 7 ์žฅ ์ถ•๊ณ„ ํšก์ง„๋™ ๋ถ„์„ 105 7.1 ํšก์ง„๋™ ๊ณ„์‚ฐ ๋ฐ ๋ถ„์„ ๋ฐฉ๋ฒ• 105 7.2 ๊ฒฐ๊ณผ ๋ฐ ๊ณ ์ฐฐ 107 7.3 ์†Œ๊ฒฐ๋ก  116 ์ œ 8 ์žฅ ๊ฐ€์† ๋ฐ ์ง์ง„์‹œ ์ถ• ๊ฑฐ๋™์ƒํƒœ ๋ถ„์„ 119 8.1 ๊ณ„์ธก ๋ฐ ๋ฐ์ดํ„ฐ ๋ถ„์„ ๋ฐฉ๋ฒ• 120 8.1.1 ์ธก์ • ์„ค๋น„์˜ ๊ตฌ์„ฑ(configuration) 120 8.1.2 ๊ณ„์ธก ์ ˆ์ฐจ 123 8.1.3 ์› ์‹ ํ˜ธ(raw data)์˜ ์ฒ˜๋ฆฌ 124 8.1.4 ์ง„๋™ ์›์ธ๋ณ„ ๊ถค๋„(orbit)ํ˜•ํƒœ ๋ถ„์„ 127 8.2 ๋™์  ์ƒํƒœ ๊ณ„์ธก(dynamic measurement) 130 8.2.1 ๋งŒ์žฌํ˜์ˆ˜ ์กฐ๊ฑด(full laden APT tank fullNBE) 139 8.3 ์†Œ๊ฒฐ๋ก  153 ์ œ 9 ์žฅ ๊ฒฐ ๋ก  155 ์ฐธ๊ณ ๋ฌธํ—Œ 157FLF) 130 8.2.2 ๋ฐธ๋Ÿฌ์ŠคํŠธ ํ˜์ˆ˜ ์กฐ๊ฑด (ballast APT tank empt

    Fabrication and evaluation of the stress induced PZT films

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    ํ•™์œ„๋…ผ๋ฌธ(๋ฐ•์‚ฌ) --์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› :์žฌ๋ฃŒ๊ณตํ•™๋ถ€,2008.8.Docto

    Sword bean์˜ ๋ฐœ์•„ํŠน์„ฑ๊ณผ ์žฌ๋ฐฐ๋ฒ•์— ๊ด€ํ•œ ์—ฐ๊ตฌ

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    ํ•™์œ„๋…ผ๋ฌธ(์„์‚ฌ)--์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› :๋†ํ•™๊ณผ,2000.Maste

    ๋ฒ ์–ด๋ง ๊ฐ•์„ฑ์„ ๊ณ ๋ คํ•œ ์ดˆ๋Œ€ํ˜• ์ปจํ…Œ์ด๋„ˆ ์šด๋ฐ˜์„ ์˜ ์ตœ์  ์ถ”์ง„์ถ•๊ณ„ ๋ฐฐ์น˜์— ๊ด€ํ•œ ์—ฐ๊ตฌ

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    Recently, damages of the main engine aftmost bearing and the after stern tube bearing tend to increase, as the shafting system becomes stiffer due to the large engine power, whereas the hull structure becomes more flexible due to optimization by using high tensile thin steel plates. Deferences of ship's draft condition and the thermal expansion are some common causative factor in the deformation of main engine bed and double bottom structure of engine room. And this is the reason that more sophisticated shaft alignments are required. Therefore, to obtain the optimum status in shafting alignment at the design stage, it is strongly recommended that the change of bearing reaction force depending on ballast/load condition, the bending moment force occurred by propeller thrust, elastic deformation of bearing occurred by vertical load of shaft mass and etc., should be considered. In this study, the optimum shafting alignment calculation was carried out, considering the number of main engine bearings, thermal expansion. and exploiting the sensitivity index, which indicates the reasonable position of forward intermediate shafting bearing for alignment. The optimal position of bearing in process for alignment is determined by sensitivity index, which is defined as follows. Sensitivity index = where, : Influence coefficient of intermediate bearing to ith bearing : Number of total bearings taken into consideration : Intermediate bearing number According to the above process, the optimal bearing position of forward intermediate shafting was confirmed with smallest sensitivity index. Finally, as the main subject in this study, the elastic deformation on main engine bearings occurred by vertical load of shaft mass were examined thoroughly and analysed allowable load of bearings, reaction influence numbers of all bearings. As the result, a reliable optimum shafting alignment was derived theoretically. To verify these results, they were referred to the engine maker's technical information of main engine installation and being used shafting alignment programmes of both Korean Register of Shipping and Det Norske Veritas, their reliability were confirmed.์ œ1์žฅ ์„œ ๋ก  1 ์ œ2์žฅ ์ถ”์ง„์ถ•๊ณ„์˜ ๋ฐฐ์น˜๋ฌธ์ œ ๋ฐ ์„ค๊ณ„๊ฐœ์š” 3 2.1 ์ถ•๊ณ„๋ฐฐ์น˜์™€ ๋ฒ ์–ด๋ง ์˜ํ–ฅ๊ณ„์ˆ˜ 3 2.2 ์ถ•๊ณ„๋ฐฐ์น˜์— ์žˆ์–ด์„œ์˜ ๋ฌธ์ œ์  3 2.3 ์ƒˆ๋กœ์šด ์ถ”์ง„์ถ•๊ณ„์˜ ๋ฐฐ์น˜๋ฌธ์ œ 5 2.4 ์ถ”์ง„์ถ•๊ณ„ ๋ฐฐ์น˜์— ์žˆ์–ด์„œ ๊ณ ๋ คํ•ด์•ผ ํ•  ์‚ฌํ•ญ 7 2.5 ์ถ”์ง„์ถ•๊ณ„ ๋ฐฐ์น˜๊ณ„์‚ฐ์˜ ์ข…๋ฅ˜์™€ ์˜๋ฏธ 8 2.5.1 ์ถ•๊ณ„์˜ ํ•ฉ๋ฆฌ์ ์ธ ๋ฐฐ์น˜ 8 2.5.2 ์ถ•๊ณ„์˜ ๋ฐฐ์น˜๋ถˆ๋Ÿ‰ 8 2.5.3 ์ถ•๊ณ„๋ฐฐ์น˜ ๋ฐฉ๋ฒ• 9 2.5.4 ์ถ”์ง„์ถ•๊ณ„ ๋ฐฐ์น˜๊ณ„์‚ฐ์˜ ๊ธฐ์ค€ 10 ์ œ3์žฅ ์œ ํ•œ์š”์†Œ๋ฒ•์— ์˜ํ•œ ์ถ•๊ณ„๋ฐฐ์น˜ ๊ณ„์‚ฐ ์ด๋ก  13 3.1 ๊ธฐ๋ณธ์‹ ์œ ๋„ 13 3.1.1 ํšกํ•˜์ค‘๊ณผ ๋ชจ๋ฉ˜ํŠธํ•˜์ค‘์„ ๋ฐ›๋Š” ๋ถ€๋“ฑ ๋‹จ๋ฉด๋ณด์˜ ์ ˆ์ ๋ฐฉ์ •์‹ 13 3.1.2 ํšกํ•˜์ค‘๊ณผ ๋ชจ๋ฉ˜ํŠธํ•˜์ค‘์„ ๋ฐ›๋Š” ๋ณด์˜ ๊ฐ•์„ฑ๋งคํŠธ๋ฆญ์Šค 16 3.1.3 ํšกํ•˜์ค‘๊ณผ ๋ชจ๋ฉ˜ํŠธํ•˜์ค‘์„ ๋ฐ›๋Š” ๋ถ€๋“ฑ๋‹จ๋ฉด๋ณด ์ ˆ์ ๋ฐฉ์ •์‹์˜ ํ•ด๋ฒ• 17 3.1.4 ๋ฐ˜๋ ฅ ์˜ํ–ฅ๊ณ„์ˆ˜์˜ ๊ณ„์‚ฐ 19 3.2 ์ถ”์ง„์ถ•๊ณ„์˜ ์ตœ์ ๋ฐฐ์น˜ ๊ณ„์‚ฐ๋ฐฉ๋ฒ• 21 3.2.1 ์ถ•๊ณ„์˜ ์ตœ์ ๋ฐฐ์น˜ ๊ณ„์‚ฐ 21 3.2.2 ์ถ•๊ณ„์˜ ์„ ํ˜•์„ฑ 22 3.2.3 ์„ ํ˜•๊ณ„ํš ๋ฌธ์ œ 24 3.3 ๊ฐญ๊ณผ ์ƒ‰์˜ ๊ณ„์‚ฐ 26 3.4 ๋ฒ ์–ด๋ง ๋ฐ˜๋ ฅ์˜ ์ด๋ก ์  ๊ณ„์‚ฐ๊ณผ์ • 28 3.5 ์žญ-์—…๋ฒ•(jack-up)์„ ์ด์šฉํ•œ ์‹ค์ œ์˜ ๋ฒ ์–ด๋ง ์ง€์ง€ํ•˜์ค‘ ์ถ”์ •๋ฐฉ๋ฒ• 31 3.6 ์žญ-์—…๋ฒ•์— ์˜ํ•œ ๋ฒ ์–ด๋ง ๋ฐ˜๋ ฅ ๊ณ„์ธก๋ฐฉ๋ฒ• 32 ์ œ4์žฅ ์‹ค์„  ์ถ•๊ณ„์˜ ์ตœ์ ๋ฐฐ์น˜ ๋ฐฉ์•ˆ ์—ฐ๊ตฌ 34 4.1 ์ด๋ก ์— ์˜ํ•œ ์ถ•๊ณ„ ๋ฒ ์–ด๋ง ๋ฐ˜๋ ฅํ•ด์„ 35 4.2 ์ถ•๊ณ„๋ฐฐ์น˜ ์ตœ์ ํ™” ์•ˆ 38 4.2.1 ์ฃผ๊ธฐ๊ด€ ๋ฒ ์–ด๋ง ๊ฐœ์ˆ˜ ๊ณ ๋ ค์— ๋”ฐ๋ฅธ ๋ฐ˜๋ ฅ ๋น„๊ต๋ถ„์„ 38 4.2.2 ์—ดํŒฝ์ฐฝ ํšจ๊ณผ ๊ณ ๋ ค์— ๋”ฐ๋ฅธ ๋ฐ˜๋ ฅ ๋น„๊ต๋ถ„์„ 40 4.2.3 ๊ฐ๋„์ง€์ˆ˜๋ฅผ ์ด์šฉํ•œ ์ค‘๊ฐ„์ถ• ๋ฒ ์–ด๋ง ์œ„์น˜์˜ ์ตœ์ ํ™” 45 4.2.4 10,100 TEU ์ถ•๊ณ„ ๋ฐฐ์น˜๋„์™€ ๊ฐ•์ฒด ๋ฒ ์–ด๋ง ๋ฐ˜๋ ฅ ๋ถ„์„ 49 4.2.5 ๊ฐ•์„ฑ์„ ๊ณ ๋ คํ•œ ๋ฒ ์–ด๋ง ๋ฐ˜๋ ฅ ๋ถ„์„ 52 ์ œ5์žฅ ๊ฒฐ ๋ก  63 ์ฐธ๊ณ  ๋ฌธํ—Œ 6

    ํ•œ๊ตญ์ธ ์ •์ƒ ์„ฑ์ธ์˜ ํ•˜๋Œ€์ •๋งฅ ํฌ๊ธฐ์˜ ์ธก์ •์„ ํ†ตํ•œ ์‹ฌ์™ธ๋„๊ด€ ํฐํƒ„์ˆ˜์ˆ ์—์„œ์˜ ๋„๊ด€ ํฌ๊ธฐ์˜ ์ ์ •์„ฑ์— ๊ด€ํ•œ ์—ฐ๊ตฌ

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    ํ•™์œ„๋…ผ๋ฌธ(์„์‚ฌ)--์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› :์˜ํ•™๊ณผ ํ‰๋ถ€์™ธ๊ณผํ•™์ „๊ณต,2004.Maste

    Electrical Tunneling Biosensor for Detecting MMP-9 Using Concentric Electrode Device

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    ํ•™์œ„๋…ผ๋ฌธ (์„์‚ฌ)-- ์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› : ์ „๊ธฐยท์ •๋ณด๊ณตํ•™๋ถ€, 2016. 2. ๋ฐ•์˜์ค€.์•”์˜ ์ค‘์š” ๋ฐ”์ด์˜ค๋งˆ์ปค (biomarker) ์ค‘์— ํ•˜๋‚˜์ธ Matrix metalloproteinase-9 (MMP-9)์„ ์ „๊ธฐ์ ์œผ๋กœ ์ธก์ •ํ•จ์œผ๋กœ์จ, ๊ฐœ์ธ์ง„๋‹จ์ด ๊ฐ€๋Šฅํ•˜๊ฒŒ ํ•˜๋Š” ํ”Œ๋žซํผ ๊ธฐ์ˆ ์„ ๊ฐœ๋ฐœํ•˜์˜€๋‹ค. MMP-9์˜ ํšจ์†Œ์—ญํ•  ํ†ตํ•ด ๋ถ„์ž ์ฒด์ธ์ด ๋Š์–ด์ง„๋‹ค๊ณ  ์•Œ๋ ค์ง„ ํŽฉํƒ€์ด๋“œ (peptide)๋ฅผ ์‚ฌ์šฉํ•˜์—ฌ, peptide์™€ ๊ธˆ ์ „๊ทน ์‚ฌ์ด์˜ tunneling ์ „๋ฅ˜์˜ ๋ณ€ํ™”๋ฅผ ์ธก์ •ํ•จ์œผ๋กœ์จ MMP-9์„ ๊ฒ€์ถœํ•˜์˜€๋‹ค. Tunneling ์ „๋ฅ˜๋ฅผ ์ฆ๊ฐ€์‹œํ‚ค๊ธฐ ์œ„ํ•ด์„œ ๊ธฐ ์‚ฌ์šฉ๋œ ์‚ฐํ™”ํ™˜์› ๋ฆฌํฌํ„ฐ (redox reporter) ์—ญํ• ์„ ํ•˜๋Š” ๋ฉ”ํ‹ธ๋ Œ ๋ธ”๋ฃจ (Methylene blue, MB)๋ฅผ peptide ๋ง๋‹จ์— ํ•ฉ์„ฑํ•œ ๋’ค ๋™์‹ฌ ๊ตฌ์กฐ ์ „๊ทน์— ๊ณ ์ •ํ™” ํ•˜์—ฌ ์‚ฌ์šฉํ•˜์˜€๋‹ค. ๋ฐ”์ด์˜ค ์„ผ์„œ๋ฅผ CMOSํšŒ๋กœ์™€ ์ง‘์ ์‹œํ‚ค๊ธฐ ์œ„ํ•ด์„œ ๋ณธ ๊ทธ๋ฃน์—์„œ ๊ฐœ๋ฐœ๋œ ๋™์‹ฌ ๊ตฌ์กฐ ์ „๊ทน์„ ์‚ฌ์šฉํ•˜์˜€๋‹ค. ๋™์‹ฌ๊ตฌ์กฐ ์ „๊ทน์€ 2์ „๊ทน ๊ตฌ์กฐ๋กœ์„œ island electrode์™€ enclosing electrode์˜ ๋ฉด์ ์ด 1000๋ฐฐ ์ด์ƒ ์ฐจ์ด ๋‚˜๊ธฐ ๋•Œ๋ฌธ์— ์ˆ˜์šฉ์•ก์— ๋Œ€ํ•œ ์ „๊ธฐ ์ด์ค‘์ธต (electrical double layer)์˜ ์ปคํŒจ์‹œํ„ด์Šค (capacitance) ์ฐจ์ด๋กœ ์ˆ˜์šฉ์•ก์˜ ์ „์œ„๊ฐ€ enclosing electrode์˜ ์ „์••์— ๊ณ ์ •๋˜๋Š” ์ž๊ธฐ-๊ฒŒ์ดํŒ… (self-gating) ํšจ๊ณผ๋ฅผ ๊ฐ€์ง€๋ฏ€๋กœ ๊ธฐ์ค€ ์ „๊ทน์ด ์—†์ด๋„ MMP-9์— ์˜ํ•œ ์ „๋ฅ˜ ๋ณ€ํ™”๋ฅผ ๊ฒ€์ถœ ๊ฐ€๋Šฅ ํ•  ๊ฒƒ์ด๋ผ ์˜ˆ์ธกํ•˜์˜€์œผ๋ฉฐ, ์ด๋ฅผ ์‹คํ—˜์„ ํ†ตํ•ด ํ™•์ธํ•˜์˜€๋‹ค. ๋ณธ ์—ฐ๊ตฌ์—์„œ๋Š” ์ „๊ทน์— ๊ณ ์ •ํ™”๋œ MB-peptide๊ฐ€ MMP-9์— ์˜ํ•ด ์ž˜๋ ธ์„ ๋•Œ์˜ ์ „๊ทน๊ณผ methylene blue ์‚ฌ์ด์˜ ์ „์ž์˜ ์ด๋™, ์ฆ‰ tunneling ์ „๋ฅ˜๊ฐ€ ๊ฐ์†Œํ•จ์„ ํ™•์ธํ•˜์˜€๋‹ค. ์ด๋Ÿฌํ•œ ํŠน์„ฑ์€ MMP-9 ์ด์™ธ์— ๋‹ค์–‘ํ•œ ๋ฐ”์ด์˜ค๋งˆ์ปค๋ฅผ ๊ฒ€์ถœํ•˜๋Š”๋ฐ ์œ ์šฉํ•˜๊ฒŒ ์‚ฌ์šฉ๋  ์ˆ˜ ์žˆ๋Š” ๋ฐ”์ด์˜ค ์„ผ์„œ ํ”Œ๋žซํผ์ด ๋  ๊ฒƒ์ด๋‹ค.์ œ 1์žฅ ์„œ ๋ก  1 1.1 ์—ฐ๊ตฌ์˜ ๋ฐฐ๊ฒฝ 1 1.2 ์—ฐ๊ตฌ์˜ ๋ชฉ์  12 1.3 ๋…ผ๋ฌธ์˜ ๊ตฌ์„ฑ 13 ์ œ 2์žฅ ์‹คํ—˜ ์„ค๊ณ„ 14 2.1 ์ง„๋‹จ ์„ผ์„œ ์†Œ์ž ๊ตฌ์กฐ 14 2.2 Peptide substrate for MMP-9 20 2.3 Tunneling state๋กœ์„œ์˜ Methylene blue (MB) 21 2.4 MB-peptide ๊ธฐ๋ฐ˜ MMP-9 ๊ฒ€์ถœ ์„ผ์„œ ์ œ์ž‘ 23 2.5 MMP-9 ์„ผ์„œ์˜ ๊ฐ์‘ ์›๋ฆฌ 25 ์ œ 3์žฅ ๊ฒฐ๊ณผ ๋ฐ ๋ถ„์„ 27 3.1 MB-peptide ๊ธฐ๋ฐ˜ tunneling biosensor์˜ ์ „๋ฅ˜ํŠน์„ฑ ๋ถ„์„ 27 3.2 ์ „์•• ์ธ๊ฐ€์— ๋”ฐ๋ฅธ MB-peptide biosensor์˜ energy state ๋ณ€ํ™” ๋ถ„์„ 33 3.3 ์‹œ๊ฐ„์— ๋”ฐ๋ฅธ ์ „๋ฅ˜ ๋ณ€ํ™” ์ธก์ • 37 3.4 MMP-9 ๋†๋„์— ๋”ฐ๋ฅธ ์ „๋ฅ˜ ๋ณ€ํ™” ์ธก์ • 39 ์ œ 4์žฅ ๊ฒฐ๋ก ๊ณผ ์•ž์œผ๋กœ ์—ฐ๊ตฌ ์ œ์•ˆ 41 ์ฐธ๊ณ ๋ฌธํ—Œ 43 Abstract 47Maste

    A Study On The Duty of Good Faith Of Real Estate Broker

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