12 research outputs found

    Mid-and long-term research plan on marine natural products

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    한국해양연구

    Bacillus sp. I-5가 생산하는 cyclodextrinase 유전자의 염기서열 분석 및 효소 특성

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    Thesis (master`s)--서울대학교 대학원 :식품공학과,1996.Maste

    Two New Sulfated Steroids from a Marine Ascidian Didemnum sp.

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    As part of our program to study on bioactive marine natural products, we have found that extracts of the ascidian Didemnum sp. exhibited cytotoxic activity against human leukemia cell line(K562). Bioassay-guided fractionation of the extracts yielded new polyhydroxylated steroids. We herein report the isolation and structure determination of two new sulfated streroids, 1 and 2. These compounds exhibited cytotoxicity against human leukemia cell line (K-562).2

    브로모페놀계 화합물, 그 제조방법 및 이를 포함하는 항균조성물

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    발명요약

    New antibiotics of the nocardamine class from a marine-derived Streptomyces sp.

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    Three cyclic peptides were isolated from the culture broth of the actinomycete Streptomyces sp. isolated from an unidentified marine sponge collected from Jaeju island. These compounds exhibited significant activity against various bacterial strains.2

    페놀계 화합물, 그 제조방법 및 이를 포함하는 항균 조성물

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    발명요약

    New bioactive macrolides from the sponge Chondrosia corticata

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    A series of oxazole-containing macrolides and related metabolites were isolated from the sponge Chondrosia corticata collected form Guam. The structures of three new compounds were defined by combined spectroscopic analyses. These compounds exhibited significant cytotoxicity toward the human leukemia cell ine K562 as well as antifungal activity toward Candida albicans.2
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