9 research outputs found

    Apoptosis in the rat cochlea induced by acute cisplatin ototoxicity

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    ํ•™์œ„๋…ผ๋ฌธ(๋ฐ•์‚ฌ)--์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› :์˜ํ•™๊ณผ ์ด๋น„์ธํ›„๊ณผํ•™์ „๊ณต,2001.Docto

    ํ”Œ๋ผ์Šคํ‹ฑ ํฌ๋งค๋ฅผ ์ด์šฉํ•œ ์ง„์ฃผ์ข…, ์™ธ์ด๋„ ํ‘œํ”ผ, ๊ณ ๋ง‰, ์ค‘์ด์ ๋ง‰์กฐ์ง์—์„œ์˜ cytokeratin ๋ถ„ํฌ์— ๋Œ€ํ•œ ๋ฉด์—ญ์กฐ์งํ™”ํ•™์  ์—ฐ๊ตฌ

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    ํ•™์œ„๋…ผ๋ฌธ(์„์‚ฌ)--์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› :์˜ํ•™๊ณผ ์ด๋น„์ธํ›„๊ณผํ•™์ „๊ณต,1995.Maste

    ์ด์ง„ํ™” ์ฃผํŒŒ์ˆ˜ ๋ณ€์กฐ ์—ฐ์†ํŒŒ ๋ผ์ด๋‹ค

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    Master๊ฐ€์žฅ ๋„๋ฆฌ ์‚ฌ์šฉ๋˜๋Š” LiDAR ๋ฐฉ๋ฒ•์ธ Direct ToF ๋ฐฉ์‹์€ ํ•˜๋“œ์›จ์–ด ๊ตฌํ˜„์˜ ํ•œ๊ณ„๊ฐ€ ๋šœ๋ ทํ•˜๋‹ค. ๋ณธ ๋…ผ๋ฌธ์—์„œ๋Š” indirect ToF ๋ฐฉ์‹ ์ค‘ ๋…ธ์ด์ฆˆ ๋ฐ ์ธก์ • ๋ฒ”์œ„์— advantage๊ฐ€ ์žˆ๋Š” FMCW๋ฅผ bainarizeํ•œ BFMCW design์„ ์ œ์‹œํ•œ๋‹ค. FMCW์˜ ๊ฒฝ์šฐ ๋…ธ์ด์ฆˆ์— ๊ฐ•ํ•˜๊ณ  ์ธก์ •๊ฑฐ๋ฆฌ๊ฐ€ ๊ธธ๋ฉฐ ์ธก์ •์‹œ๊ฐ„์ด ๋น ๋ฅด๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ FMCW ๊ตฌํ˜„์„ ์œ„ํ•ด light์˜ intensity ํ˜น์€ wavelength๋ฅผ modulation ํ•˜๋Š”๊ฒƒ์€ ๋ณต์žกํ•œ photonic device๊ฐ€ ํ•„์š”ํ•˜๋ฉฐ ์ˆ˜์‹ ๋œ ์‹ ํ˜ธ๋ฅผ mixing ํ•˜๋Š”๋ฐ๋„ optical interferometer๊ฐ€ ํ•„์š”ํ•˜๋‹ค. ์ด๋Ÿฌํ•œ ๋‹จ์ ์„ ๊ทน๋ณตํ•˜๊ธฐ ์œ„ํ•ด DAC์™€ ADC ๋ฅผ ์ด์šฉํ•˜์—ฌ light์˜ intensity๋ฅผ ์ง์ ‘ ๋””์ง€ํ„ธ๋กœ ์ œ์–ดํ•˜๊ณ  ์ˆ˜์‹ ํ•˜๋Š” ๋ฐฉ๋ฒ•์ด ์ œ์‹œ๋˜์—ˆ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ ์ด ๋ฐฉ๋ฒ•์€ laser๋ฅผ ๋ฐœ์ง„ํ•˜๋Š” ์‹ ํ˜ธ๋ฅผ DAC์—์„œ ์ƒ์„ฑํ•˜๊ธฐ ๋•Œ๋ฌธ์— chirp bandwidth์˜ ์ˆ˜ ๋ฐฐ์— ๋‹ฌํ•˜๋Š” ๋งค์šฐ ๋น ๋ฅธ DAC๊ฐ€ ํ•„์š”ํ•˜๊ณ  ํ•ด๋‹น bandwidth ๋ฅผ ์ธก์ •ํ•  ์ˆ˜ ์žˆ๋Š” ADC ๋˜ํ•œ ํ•„์š”ํ•˜๋‹ค. ๋ณธ ์—ฐ๊ตฌ์—์„œ๋Š” LFM ์‹ ํ˜ธ๋ฅผ Binarizeํ•œ BFM์‹ ํ˜ธ๋ฅผ ํ†ตํ•ด ๊ธฐ์กด FMCW ๋ผ์ด๋‹ค์˜ ๋ณต์žกํ•œ ๊ด‘ํ•™์  ์†ก์ˆ˜์‹ ๊ธฐ๋ฅผ BFM๊ธฐ๋ฐ˜ switching modulator์™€ switching mixer๋กœ ๋Œ€์ฒดํ•œ BFMCW ์„ค๊ณ„๋ฅผ ์ œ์‹œํ•œ๋‹ค. ์ด๋ฅผ ๊ฒ€์ฆํ•˜๊ธฐ ์œ„ํ•ด ๋‘ ๊ฐ€์ง€ simulation์„ ์ˆ˜ํ–‰ํ•˜์˜€๋‹ค. ์ฒซ๋ฒˆ์งธ simulation์€ ๊ธฐ์กด์— ์ œ์‹œ๋œ DAC-ADC ์‹œ์Šคํ…œ์˜ receiver์— 0MHz์—์„œ 30MHz ๊นŒ์ง€ sweepํ•˜๋Š” 100ฮผs ๊ธธ์ด์˜ LFM์‹ ํ˜ธ์™€ BFM์‹ ํ˜ธ๋ฅผ ์ž…๋ ฅํ•˜์—ฌ signal processing์„ ํ†ตํ•ด ๋™์ผํ•œ 301.98kHz์˜ beat frequency๊ฐ€ ๋‚˜์˜ค๋Š” ๊ฒƒ์„ ํ™•์ธํ•˜์˜€๋‹ค. ๋‘ ๋ฒˆ์งธ simulation์—์„œ๋Š” ๋ณธ ์—ฐ๊ตฌ์—์„œ ์ œ์•ˆํ•œ ๊ตฌ์กฐ์ธ switching mixer receiver์— ๋Œ€์ƒ์—์„œ ๋ฐ˜์‚ฌ๋œ beat frequency๋ฅผ ์ž…๋ ฅํ•˜์—ฌ beat frequency๊ฐ€ ๋‚˜์˜ค๋Š”์ง€ ํ™•์ธ ํ•˜์˜€๋‹ค. beat frequency์˜ ์ฃผํŒŒ์ˆ˜๋ฅผ ํ†ตํ•ด 30cm์˜ ํ‘œ์ค€ํŽธ์ฐจ๋กœ ๊ฑฐ๋ฆฌ๋ฅผ ์ถ”์ถœํ•  ์ˆ˜ ์žˆ๋‹ค๋Š” ๊ฒƒ์„ ํ™•์ธ ํ•˜์˜€๋‹ค.Direct ToF, which is the most widely used LiDAR method, has certain limitations in hardware implementation. In this paper, I propose a BFMCW design which is the binarized FMCW method, which has an advantage in noise and measurement range among indirect ToF methods. In the case of FMCW, it is resistant to noise, has a long measurement distance, and has a fast measurement time between the indirect ToF method. However, modulating light intensity or wavelength for FMCW requires a complex photonic device, and mixing the received signal requires an optical interferometer. To overcome these disadvantages, a method of digitally controlling and receiving light intensity using a DAC and ADC has been proposed. However, since this method generates a laser oscillating signal from the DAC, DAC that has several times bigger sampling rate than the chirp bandwidth is needed, and high-speed ADC capable of measuring the chirp bandwidth is also required. This study proposes a BFMCW LiDAR design that replaces the complex optical transceiver of existing FMCW LiDAR with switching modulator and switching mixer through BFM signal which is binarized LFM signal. Two simulations were performed to verify the BFMCW LiDAR design. The first simulation confirmed that the same 301.98kHz beat frequency was generated through signal processing by inputting a 100ฮผs LFM and BFM chirp signal sweeping from 0MHz to 30MHz in the receiver of the previously proposed DAC-ADC system. In the second simulation, the BFM chirp signal which is based on modeling of reflection from the target transmitter and receiver optics was input to the switching mixer based BFMCW receiver, which is the structure proposed in this study. It was confirmed that the distance can be extracted with a standard deviation of 30 cm through the beat frequency
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