전자상거래의 조세문제에 관한 문헌 및 사례연구

학위논문(석사)--서울대학교 대학원 :경영학과 회계학전공,2000.Maste

공적개발원조의 관점에서 본 남북협력기금의 효과성 연구

Thesis(masters) --서울대학교 국제대학원 :국제학과(국제협력전공),2010.2.Maste

1980년대 한국 여성미술 운동 : 페미니즘 미술로서의 성과와 한계

학위논문(석사)--서울대학교 대학원 :서양화과 미술이론전공,2000.Maste

Jurkat T 세포에서 Survivin이 세포 주기 중 G1 단계에 의존적인 자극에 의한 세포사를 조절하는 기작

학위논문(석사) - 한국과학기술원 : 생물과학과, 2002.2, [ vi, 59 p. ]Peripheral T cell tolerance after negative selection of self-reactive T cells and deletion of hyperactivated T cells following the immune response occur through an apoptosis termed activation-induced cell death (AICD). The susceptibility to AICD is controlled by the cell cycle, and the cells in Gl phase are sensitive to AICD. We have investigated the molecular mechanism of cell cycle-mediated AICD and the expression of Survivin, an inhibitor of apoptosis protein (IAP) family. The mRNA analysis of Survivin showed that the expression of Survivin was decreased after AICD induction. The activity of caspase-3 was highly upregulated in G1 phase after AICD induction. No Survivin mRNA was observed in G1 phase, whereas the high level of Survivin was expressed in G2/M phase. Overexpression of Survivin by a Survivin cDNA vector, blocked the G1 phase-dependent AICD. In contrast, the loss of function of Survivin by dominant-negative vector, sensitized T cells to AICD. These results suggest that. Survivin presumably regulates the G1 phase-dependent AICD in Jurkat T cells.한국과학기술원 : 생물과학과