포유돈 사료 내 셀레늄 형태 및 첨가수준이 모돈 및 자돈의 생리적 변화, 포유능력, 혈액성상, 돈유성분 및 조직 내 셀레늄 농도에 미치는 영향

학위논문(석사) -- 서울대학교대학원 : 농업생명과학대학 농생명공학부, 2022.2. 김유용.Recently, in a situation where consumers’ interest in well-being is increasing, many foods fortified with bioactive substances are being released according to this trend. In nature, selenium exists in two chemical forms: organic and inorganic. Among them, organic selenium has a higher retention rate, higher tissue accumulation and antioxidant bioavailability, and low toxicity and environmental pollution than inorganic selenium. So, replacing the conventional inorganic Se with organic Se in animal feed has recently attracted by feed industry although organic form of selenium is much more expensive. However, production of selenium fortified animal products is not well developed in market of animal food because supplementation level of selenium in feed is very low and bioavailability of selenium is different by levels and sources. Therefore, this study was conducted to investigate the effect of selenium benefits on lactating sows on physiological responses, litter performance, blood profiles and milk composition when mixed form of selenium was provided in lactation diet. A total of 45 F1 multiparous sows (Yorkshire × Landrace) with average body weight (BW) of 241.8 ± 3.57 kg, backfat thickness of 18.9 ± 1.76 mm, and parity of 3.50 ± 0.440 were allotted to one of 4 treatments considering BW, backfat thickness, and parity in a complete randomized design (CRD) with 15 replicates. Treatments were 1) Con; corn-SBM based diet; 2) ISOS15; corn-SBM based diet + inorganic selenium 0.15 ppm + organic selenium 0.15 ppm; 3) ISOS25; corn-SBM based diet + inorganic selenium 0.25 ppm + organic selenium 0.25 ppm. As a result, during the lactation period, the mixing levels of organic and inorganic selenium did not show difference in body weight and backfat thickness of lactating sows. In addition, litter weight and piglet weight were not changed by different levels of dietary selenium in sow’s diet. Additionally, the milk composition of lactating sows was not altered by different levels of dietary selenium. When sows were fed ISOS15 and ISOS25 treatment diet, ADFI was increased numerically compared to control but there were no differences in body weight and backfat thickness of sows. When sows were fed selenium treatment diets, selenium in blood was clearly increased at 7 d of lactation both in sow and piglets (P<0.01) and maintained plateau after time. Liver selenium in piglets tended to increase when dietary selenium was provided to sows. However, selenium contents in kidney and muscle were higher as dietary selenium was increased, respectively (P=0.03, P=0.04). This experiment demonstrated that dietary selenium can be transferred efficiently from sows to piglets subsequently adequate level and source of selenium should be suggested. Moreover, selenium fortified pork can be produced if adequate level and source of selenium is utilized in diets for grower-finisher pigs.I. General Introduction 1 II. Review of Literature 3 1. Introduction 3 2. Requirements of selenium 4 3. Characteristics of selenium 7 3.1. Functions of selenium 8 3.2. Deficiency of selenium 8 3.3. Toxicity of selenium 9 4. Different sources of selenium 10 4.1. Organic selenium 11 4.2. Inorganic selenium 12 4.3. Comparison of organic and inorganic selenium 13 5. Effects of supplementation of selenium in lactating sow and their progeny 14 5.1. Maternal effect on progeny 14 5.2. Secretion milk or colostrum 15 Ⅲ. Effects of Sources and Levels of Selenium on Physiological Responses, Litter Performance, Blood Profiles, Milk Composition and Tissue Concentration in Lactating Sows and Their Progeny Abstract 17 Introduction 19 Materials and Methods 21 Results and Discussion 27 Conclusion 33 Ⅳ. Literature Cited 40 Ⅴ. Summary in Korean 56석