71 research outputs found
The Teachers' Recognition on 'Technology and Invention' Unit's Training in Technology/Home Economics
The Histo-pathological and Histo-chemical Studies on the Effects of Acute and Chronic Carbon Monoxide Poisoning in Gestated Rat Uterus
Carbon monoxide poisoning is very common home
accident and one of the main health hazards in
Korea, since Koreans use anthracite coal briquette as
domestic fuel. Among the many harmful effects of
CO poisoning, it is noteworthy that it increases the
pregnancy wastage rate and, in milder cases, impedes
the fetal development. But, in spite of the importance
of the CO poisoning in pregnancy, there have been very few reports on the histo-pathological changes.
which happen in the uterus of pregnant woman.
This study was designed to investigate the histo-pathological
and histo-chemical changes of CO poisoning
in gestated uterus. Gestated rats exposed to carbon
monoxide gas of 4, 500~5, OOOppm for 20 minutes at
the 16th Gestation day comprise acute CO poisoning
group. Chronic poisoning group were exposed to COยท
gas of 400ppm for 8 hours from 13th to 16th day of
the Gestation, therefore the total duration of exposure
was 32 hours. Among twenty three rats in each
group, eight were sacrificed at the end of the exposure
to observe the changes at the moment. The rest
fifteen were observed at the 20th gestation day that
is just before the spontaneous delivery. And, as control
groups, eight gestated rats were observed at the
16th day and thirty at the 20th day of the gestation.
The plain H&E staining and also histo-chemical'
staining were made to observe the extracted rat uteri.
Investigated enzymes were NADH diaphorase, SDH,_
LIm, alkaline phosphatase, and acid phosphatase.
Following results were observed:
1. In acute poisoning group sacrificed at the 16th
day, fibrinoid necrosis and infiltration of lymphatic
cells were observed in subplacental myometrium, and
the congestion was found in the inner myometrium.
In chronic exposure group, the common finding wasmild
congestion. In acute exposure group observed
at the 20th day, myometrium showed mild congestion
and lymphatic infiltration, but in chronic exposure
group, there was no difference from normal control
group of the same date.
2. The activity of NADH diaphorase was reduced
in both acute and chronic groups at the 16th day.
It regained the normal value at the 20th day.
3. The activity of SDH was reduced in both acute
and chronic exposure groups at the 16th day, but it
returned to the level of normal control group at the
20th day.
4. The activity of LDH was reduced in acute ex'
posure group at the 16th day, but increased in
chronic exposure group of the same date. At the 20th
day, both showed no difference from normal control
group.
5. The activity of alkaline phosphatase was redu-ced in both groups at the 16th day. At the 20th day
there was no difference between poisoning groups
.and control group.
6. The activity of acid phosphatase was low at the
16th day, but it showed almost same level with normal
control group at 20th day
An Epidemiological Investigation on the Outbreak of Diarrheal Illness in an Urban Slum Area in Seoul
From April 24 to June 4, 1979, an outbreak of
diarrheal illness was observed in an urban slum area
in SeouL For the purpose of elucidation of the
causal mechanism of the causative agent and the
mode of transmission in this outbreak, the authors
tried an epidemiological investigation.
Following conclusions are drawn:
L By questionnaire survey 97 cases with diarrheal
illness were detected. In three among seven diarrheal
cases whose stool specimen could be collected,
Shigella flexneri was confirmed by microbiological examination.
2. This illness was clinically characterized by
dlarrhea, tenesmus, abdominal cramp and fever.
Median duration of illness in the detected cases was
five days.
3. Incidence rate in surveyed population was 6.7
%. Especially, incidence rate of 0~4 year age group
was extremely high as 29.3%. Incidence rate by sex
was not significantly different.
4. Incidence rate was 9.1% in population using
simple piped water supply system. Difference of
incidence rate between these two groups was highly
significant (p<O.OO.
Conclusively, simple piped water supply system
played an important role as common vehicle in the
outbreak of this diarrheal illness
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