한국언론에 나타난 국제화.세계화 담론의 구조와 변화에 대한 비교 연구 : 조선일보와 한겨레신문을 중심으로

학위논문(석사)--서울대학교 대학원 :신문학과,1995.Maste

가토의 두개골 결손부에서 골재생에 끼치는 골막의 역할

The role of the periosteum on osteointegration of (Geistlich, Wolhusen/Switzerland) was studied in rabbit calvarial defect. 12 New Zealand white male rabbits between 2.8 and 4 kg were included in this randomized, blinded, prospective study. Each rabbit was anesthetized with Ketamine HCl(5 mg/kg) and Xylazine HCl(1.5 ml/kg). An incision was made to the bony cranium and the periosteum was reflected. Using a 6-mm trephine bur(3i. USA), four 8-mm defects were created with copious irrigation. The defects were classified into barrier membrane(, Lifecore Biomedical. Inc, U.S.A.) only group as a control, with barrier membrane group, with periosteum covering group, and without periosteum covering group. There were 2 rabbits in each group. The wound was closed with resorbable suture materials. Rabbits were sacrificed using phentobarbital(100 mg/kg) intravenously at 1, 2, and 4 weeks after surgery. The samples were fixed in 4% paraformaldehyde, and decalcified in hydrochloric acid decalcifying solution(Fisher Scientific, Tustin, CA) at for 2-4 weeks. It was embedded in paraffin and cut into 6 thickness. The sections were stained with H & E and observed by optical microscope. The results were as follows; 1. The periosteum played an important role in osteointegration of in bone defects. 2. When the periosteum remained intact and was placed on the defect, with periosteum covering has been incorporated into the newly formed bone from 2-week postoperatively. 3. When the periosteum was removed at the surgical procedure, invasion of connective tissue took place among the granules, and new bone formation was delayed compared to periosteum covering group. Therefore, when the bone grafting was performed with periosteal incision procedure to achieve tension-free suture, the integrity of the overlying periosteum should be maintained to avoid fibrous tissue ingrowth.이 논문은 2004년도 조선대학교 학술연구비의 지원을 받았습니다