151 research outputs found
A Curriculum Reform on University Teaching of Visual Communication Deasign at the New era
随着我国当前社会经济的发展、市场经济的转型和创意产业的兴起,我国设计教育领域迎来了前所未有的发展契机。面对发展创新型国家的战略机遇,设计教育如何培养出更多优秀的设计人才,成为设计教育界面临的严峻挑战。 而我国目前的设计教育还存在诸多问题。学校是教育人才培养的基地,而学校在培养人才的过程中在形式上一味追逐社会发展的脚步,却忽视了设计人员的质量培养,造成了目前设计人员数量与质量的不平衡。本文从我国目前视觉传达设计的教学现状出发,分析眼下设计人才培养中存在的种种问题,并结合国外发达国家的教学经验,提出对当下视觉传达设计专业课程改革的建议,以期对我国当前的设计教育改革有所启示。 本文共分为四个章节...With our current economic and social development and the rise of creative industries, Design education in China has embraced an unprecedented development opportunity. In the face of strategic opportunity of the development of an innovative country how to cultivate more excellent design talent in design Education is becoming a challenge of design education. But,there are many problems in our desi...学位:文学硕士院系专业:艺术教育学院美术系_美术学学号:1862007115165
Cognitive Psychology and the English Translation of Tao
中国传统哲学概念植根于中国文化的土壤,具有与西方文化显著不同的特点。这种独特性使得几百年来无数翻译者在面对此类概念时遇到了巨大的挑战。为此,翻译者们运用了各种不同的翻译策略,试图把最为“正确”的译文传递给受众。然而,几百年来对于何为“正确”的译文的争论从来没有间断过。如果我们跳出争论,从另外一个角度看待此类翻译问题,把关注的重心从翻译的结果转向翻译的过程,也许各种不同的译文并没有所谓的“正确”与否之分,都有其存在的价值。 本文从认知心理学的角度出发,以中国传统哲学概念“道”的英译历程为研究范本,认为在中国传统哲学概念的翻译领域存在着一个共同的翻译模型,即从音译到音译和意译并存再到以音译为主,...Chinese traditional philosophical concepts are rooted in Chinese culture and are quite different from those in western culture. This has become a huge challenge for thousands of translators for centuries in translating these concepts. To meet the challenge, translators have used different translation strategies and tried to present to their audience the most ‘correct’ translations. However, in the...学位:文学硕士院系专业:外文学院英语语言文学系_英语语言文学学号:X200711000
新媒体时代传播研究转型问题分析
新媒体时代给媒体传播带来一定的影响,从而引起了传播学界观念的变化。而伴随着媒体传播的变化发展,在传播认识、传播技术和传播活动方面,传播研究的内容也开始发生变化。本文在分析新媒体时代传播研究转型情况的基础上,对传播研究在新媒体时代的转型策略展开了探讨
Accumulation,transformation and depuration of parlytic shellfish toxins by the scallop Patinopecten yessoensis
以我国麻痹性贝毒高发区的虾夷扇贝为研究对象,研究了麻痹性贝毒在扇贝各组织内的累积、转化和排出过程。实验分为洁净海区吊养排毒和室内投喂有毒藻累毒两部分。排毒实验表明,内脏团和鳃排毒率最快,为3.27%/d,外套膜为2.71%/d,证明虾夷扇贝属慢性排毒者。累毒过程中扇贝无不良反应,累毒实验第2 d(A2)扇贝总毒性即达到19.41μgSTXEQ/g(干质量),说明虾夷扇贝对麻痹性毒素敏感性低、累积快、累积量大,不同组织对毒素的累积速率差异不大,在4.80%~4.98%/d之间。内脏团及外套膜始终是毒素最主要的分布组织,占总毒素95%以上,闭壳肌最少。扇贝各组织中毒素组分的复杂性与其毒性正相关,且毒素间有转化现象,内脏团和外套膜是最主要的转化组织。主要转化类型有:gTX1,4被还原成gTX2,3;gTX2,3转化为STX;STX转化为dCSTX以及α、β异构体的相互转化。This study investigated the accumulation,transformation and depuration of paralytic shellfish toxin(PST) in the scallop Patinopecten yessoensi collected from the PST-contaminated area.Two experiments were conducted:in situ depuration of PST in non-PST contaminated sea area and accumulation of PST in laboratory.In the depuration experiment,the visceral mass and gill presented the faster detoxification rate than the mantle,and the average toxin depuration rate reached 3.27% and 2.71% per day,respectively,indicating P.yessoensis was belong to the slow detoxification bivalve.In the accumulation experiment,the total toxicity of the scallop reached 19.41 μg STXeq/g(dry weight)at day two(A2) and no adverse effects were observed during the accumulation experiment,suggesting P.yessoensis has low sensitivity,high tolerance ability to PST with a fast accumulation rate.There was no obvious discrepancy(4.80%~4.98%/day) in accumulation rate between different tissues of P.yessoensis.Toxin content presented the positively correlation ship with the toxin profiles,the visceral mass and mantle contained the higher toxin content and more toxin profiles,while the adductor muscle contained the least.Toxin biotransformation in P.yessoensis was tissues-specific.Transformation in visceral mass and mantle was more significant and the main toxin biotransformation forms occurred as the followings:N-OH toxin GTX1,4 was converted into N-H toxins GTX2,3,GTX2,3 was converted into dcSTX,STX was converted into dcSTX,as well as the reciprocal transformation between isomeric compounds
The measure of active learning state among healthcare undergraduates
2005-2006 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
间充质细胞外泌体促进小鼠胰岛内皮细胞血管生成的研究
目的探讨间充质细胞(MSC)外泌体对低氧条件下胰岛内皮细胞(MS-1)血管生成的影响。方法 MSC无血清低氧条件培养48 h,超滤离心法富集条件培养基中的外泌体,采用电镜和Western Blot的方法进行鉴定;通过血管形成试验比较分析不同条件下:常氧培养组(NOR组,21%O2、5%CO2)、低浓度氧培养组(HYP组,2%O2、5%CO2)、外泌体+低浓度氧共培养组(HYP+EXO组,2%O2、5%CO2),MS-1细胞的血管形成能力;image J软件分析血管形成长度;PCR、Q-PCR检测血管内皮生长因子(VEGF) RNA水平的表达,Western Blot检测VEGF、HIF1α蛋白水平表达以及mTOR信号通路激活情况。采用单因素方差分析和SNK-q检验统计学分析。结果超滤离心法富集的MSC条件培养基中的外泌体,大小为30~100 nm,表达CD9,CD63,CD81等外泌体表面标志物;血管形成试验结果显示,低氧促进MS-1血管生成,HYP+EXO组形成明显的血管网状结构;HYP+EXO组血管形成相对长度(2386.0±137.7)像素与NOR组(393.3±174.2)像素和HYP组(1467.0±230.0)像素相比增强,差异有统计学意义(t=12.30,P=0.0065;t=15.74,P=0.0040); PCR结果显示,HYP+EXO组VEGF相对表达量(20.26±9.972)较常氧对照组(1.000)和低氧组(6.521±3.501)均增强,差异有统计学意义(t=5.462,P=0.0009;t=4.238,P=0.0038);同时,Western Blot结果显示VEGF蛋白水平表达升高,HIF1-α表达上调,mTOR发生磷酸化。结论 MSC外泌体可促进低氧条件下的小鼠胰岛内皮细胞血管生成。MSC外泌体可能通过上调HIF1-α,调节VEGF表达,激活mTOR信号通路,促进胰岛内皮细胞血管生成。国家自然科学基金青年项目(81601618);;福建省自然科学基金面上项目(2016J01582、2016J01580、2018J01349);;福建省科技创新联合资金重大项目(2017Y9127
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