不同形貌普鲁士蓝纳米粒子的合成及光热性能

制备了立方体、直角立方体、球形、棒状、中空状、核壳状、梭形、多面体等8种不同形貌的普鲁士蓝纳米粒子,利用扫描电子显微镜、透射电子显微镜、紫外-可见分光光度计等对纳米粒子进行了表征,考察了普鲁士蓝纳米粒子光热性能的影响因素.结果表明,普鲁士蓝纳米粒子的形貌与光热性能之间联系密切,粒子形貌不同,光热性能不同;当外部实验条件一定时,纳米粒子的形貌、大小、吸收横截面积、尖锐化程度及密实程度等对其光热性能有很大的影响;当纳米粒子形貌一定时,外部因素如激光器的选择、激光功率密度及纳米粒子的浓度等直接影响普鲁士蓝纳米粒子的光热性能;在相同浓度下,激光功率密度越大,纳米粒子的升温效果越明显,光热性能越好;而激光功率密度不变时,纳米粒子浓度越大,其光热转换效率越高.国家自然科学基金(批准号:31271071,31371012,U1505228)资助~

不完全性脊髓损伤患者主要照顾者负性情绪与创伤后成长的纵向研究

目的探讨不完全性脊髓损伤患者主要照顾者在其治疗不同时期负性情绪与创伤后成长的纵向变化及二者之间的关系。方法以不完全性脊髓损伤患者主要照顾者76例作为研究对象,采用心境和焦虑症状问卷、创伤后成长量表在术前、术后进行问卷调查。结果心境和焦虑症状总分术后三个月(50.34±3.46)与术前(57.23±9.06)、术后一周(56.89±9.03)相比有显著差异,术后一个月心境和焦虑症状总分(52.30±9.05)与术后一周(56.89±9.03)相比有显著差异,差异有统计学意义(P<0.05);术后三个月创伤后成长总分(62.43±11.03)与术前(56.72±12.75)、术后一周(58.71±14.63)相比有显著差异,术后一个月创伤后成长总分(60.12±14.48)与术后一周(58.71±14.63)相比有显著差异,差异有统计学意义(P<0.05)。结论负性情绪各维度与创伤后成长相关。负性情绪各维度与创伤后成长总分、新的可能性、个人力量、自我转变相关

Dynamic Selection of Materialized Views of Multi Dimensional Data with a Multi-Users and Multi Windows Method

多维视图动态维护是数据仓库领域当前研究的一个热点 随着数据仓库的普及 ,将有越来越多的各种类型的用户使用OLAP工具满足各自特定的分析需求 现有的各种视图选择方法没有考虑不同类型用户的特点 ,从而存在一些缺陷 提出多用户多窗口方法 ,充分考虑用户的差异 ,利用单个用户在查询时的相对有规律性 ,为用户划分级别 ,并为每个用户设置相应级别的用户视图窗口 ,从而合理地利用了系统有限的资源 ,提高了查询响应速度 ,也保证了特殊用户对查询性能的特殊需求 ;给出了相关的定义和MUMW算法 ,并阐述了多用户多窗口方法的优点Dynamic selection of materialized views of multi dimensional data is one of the most researched aspects in the field of data warehouse; With the increasing use of data warehouse, there will be accordingly more and more different kinds of users making use of OLAP tools to complete their analytical work; The existing methods being used to select views do not take into account the characteristic of various kinds of users, and therefore have some defects; A multi users and multi windows method is presented here, which considers the disparity among various users and makes use of the rule of the users' queries In the method, all users are divided into three groups with different grade and each user is accordingly endowed with user view window of certain grade Such method leads to the reasonable use of the limited space resource and also speeds up the response of query, which stipulates satisfying some special needs of certain user; Some related conceptions and MUMW algorithm are also put forward here, and at the same time, the advantages of this method are described福建省自然科学基金项目 (A0 3 10 0 0 8);; 福建省高新技术研究开放计划重点项目 ( 2 0 0 3H0 43

Dynamic Selection of Materialized Views of Multi-Dimensional Data with a Multi-Users and Multi-Windows Method

多维视图动态维护是数据仓库领域当前研究的一个热点 随着数据仓库的普及 ,将有越来越多的各种类型的用户使用OLAP工具满足各自特定的分析需求 现有的各种视图选择方法没有考虑不同类型用户的特点 ,从而存在一些缺陷 提出多用户多窗口方法 ,充分考虑用户的差异 ,利用单个用户在查询时的相对有规律性 ,为用户划分级别 ,并为每个用户设置相应级别的用户视图窗口 ,从而合理地利用了系统有限的资源 ,提高了查询响应速度 ,也保证了特殊用户对查询性能的特殊需求 ;给出了相关的定义和MUMW算法 ,并阐述了多用户多窗口方法的优点。Dynamic selection of materialized views of multi-dimensional data is one of the most researched aspects in the field of data warehouse; With the increasing use of data warehouse, there will be accordingly more and more different kinds of users making use of OLAP tools to complete their analytical work; The existing met hods being used to select views do not take into ccount the characteristic of various kinds of users, and therefore have some defects; A multi-users and multi-windows method is presented here, which considerst he disparity among various users and makes use of the rule of the users’queries1 In the method,all users are divided into three group swith different grade and each user is accordingly endowed with user view window of certain grade. Such met hod leads to the reasonable use of the limited space resource and also speeds up the response of query, which stipulates satisfying some special needs of certain user; Some related conceptions and MUMW algorithm are also put forward here, and at the same time , the advantages of this method are described.福建省自然科学基金项目(A0310008);福建省高新技术研究开放计划重点项目(2003H043

A new dynamic indexing structure for searching time-series patterns

We target at the growing topic of representing and searching time series data. A new MABI (Moving Average Based Indexing) technique is proposed to improve the performance of the similarity searching in large timeseries databases. Notions of Moving average and Euclidean distances are introduced to represent the time-series data and to measure the distance between two series. Based on the distance reducing rate relation theorem, the MABI technique has the ability to prune the unqualified sequences out quickly in similarity searches and to restrict the search to a much smaller range, compare to the data in question. Finally the paper reports some results of the experiment on a stock price data set, and shows the good performance of MABI method

--1H-NMR Spectroscopy-based Metabonomic Research on Serum of Model Rats of Wilson's Disease

目的:以基于核磁共振(nMr)的代谢组学方法对WIlSOn病大鼠模型及正常对照组大鼠血清进行研究,分析血清中小分子代谢物的变化,从小分子代谢物层面上探讨WIlSOn病的内在机制,以更加清楚的认识本病。方法:22只雄性WISTAr大鼠,体重(180±20)g,随机被分为模型组(n=11)和健康对照组(n=11),采用铜负荷法制作WIlSOn病大鼠模型,以核磁共振(nMr)技术对大鼠血清进行检测。采用MESTrE-C 2.3软件及自编软件对谱图进行手动调相、基线校正和谱峰对齐。对样品进行分段积分,将积分数据归一化后构成数据矩阵,并利用PCA方法对数据矩阵进行统计分析。结果:相对于正常对照组,模型组大鼠血清甜菜碱(bETAInE)、氧化三甲胺(TAMO)、低密度脂蛋白(ldl)、极低密度脂蛋白(Vldl)、葡萄糖(gluCOSE)含量有显著降低,胆碱(CHOlInE)、胆碱磷酸(PHOSPHOrylCHOlInE)的含量有所降低,乳酸(lACTATE)、谷氨酰胺(gluTAMInE)、糖蛋白(glyCOPrOTEIn)有显著升高,肌氨酸+肌氨酸酐(CrEATInE+CrEATInInE),精氨酸(ArgInInE)有所升高。这些发生改变的代谢物可以作为Wd的小分子代谢标志物,为进一步研究Wd的内在代谢机制提供参考。Objective:Applying 1H nuclear magnetic resonance(1H-NMR)spectroscopy-based metabonomic approach to investigate the changes of small molecular metabolites in the serum from the rats of the model group of Wilson's disease contrasted with those of the control group.Exploring the pathogenesis of Wilson's disease from small molecular aspect.Methods:22 male Wistar rats[weight=(180±20)g]were divided into two groups randomly,the model group(n=11)and the control group(n=11),with the models established with excessive copper method.The serum was tested with 1H-NMR technology.The spectra were edited with MestRe-C2.3 and self-programmed software and then principal component analysis(PCA)was applied to differentiate the two groups.Results:Choline and phosphorylcholine concentrations were found to be lower and TAMO+betaine,LDL,VLDL and glucose were significantly lower in the serum of the model group.While creatinine and arginine concentrations were found to be higher and lactate,glutamine and glycoprotein were significantly higher in the model group.The small molecular metabolites above may contribute to the discrimination,and serve as references for further research on WD pathogenesis.“十一五”国家科技支撑计划分课题重大疑难疾病中医防治研究项目(2006BA104A02

含氟聚硅氧烷的结构与性能研究

以含氢硅油、丙烯酸全氟己基乙基酯(APHEE)为原料,氯铂酸为催化剂,采用硅氢加成合成了含氟聚硅氧烷.通过红外光谱仪、光学接触角测量仪、差式扫描量热仪对产物结构进行表征分析,探讨了不同组分比例对产物性能的影响,并研究了不同固化剂对产物固化性能的影响及不同阻聚剂对产物储存稳定性的影响.结果表明:APHEE组分比例越大,含氟聚硅氧烷的憎水憎油性能越好.异辛酸铅的固化活性最大,添加N,N-二甲基甲酰胺的产物储存稳定性最好

要勇敢面对一流本科教育这个世界性难题(笔谈)

本科教育是培养高层次人才的根本,也是培养科学创新型人才的起点。"双一流"建设背景下,建设一流本科教育日益成为社会共识,因为一流本科教育是一流大学之基。一流本科教育离不开高质量教学,高质量教学相信学生具有理性探究能力,只有坚持平等性、建构性和个性化原则,把能力培养作为教学的中心任务,才能进行有效的教学创新。合作学习是教学生态重建的抓手,也是提高教学质量、促进教学创新的一个重要向度。高质量教学需要可靠的保障机制,学生课程评估已成为高校教学质量保障体系的重要一环。但课程评估的主要目标是通过反馈以帮助教师改进教学,而不是对教师教学质量实施"监控"。一流本科教育最根本的标志是能够培养出一流人才,对"拔尖学生"的培养自然而然就成了人们关注的一个重点,学习投入、学习方法、学习情绪等"过程性指标"应成为关注的核心。一流人才的培养需要教学和科研发挥各自优势,协同育人。同时,一流本科教育依赖于一流的专业教育,一流的专业教育必须实现对传统专业教育模式的超越。教育部人文社会科学重点基地重大项目“中国特色的大学治理结构与质量保障机制建设研究”(项目编号:18JJD880005);教育部人文社会科学重点研究基地重大项目“经济新常态下的教育财政研究”(项目编号:16JJD880002)国家社科基金教育学一般项目“‘创新战略’背景下中国一流大学‘拔尖计划’本科生的深层学习研究”(BIA180169);国家社科基金“十三五”规划(教育类)一般课题“‘双一流’建设大学教学和科研协同育人机制研究”(项目编号:BIA180163)山东省高等教育改革与发展研究院重大委托项目“中国特色高等教育质量治理体系建构研究

CCCCC pentadentate chelates with planar Möbius aromaticity and unique properties

本课题充分发挥了厦门大学多学科协同研究优势，通讯作者为夏海平教授（合成、表征）、刘刚教授（生物医学应用）和吕鑫教授（理论计算）。合成实验和结构表征由朱从青（第一作者，目前在麻省理工学院、2005年诺贝尔化学奖得主Richard Schrock教授课题组从事博士后研究）完成；生物医学应用由杨彩霞（共同第一作者）、林凎、杨宇惠、王晓勇合作完成；理论计算由朱军、王永恒、朱从青完成。美国NIH的陈小元教授参与了生物医学应用的讨论。该研究工作得到国家自然科学基金委、科技部项目的支持。The coordinating atoms in polydentate chelates are primarily heteroatoms. We present the first examples of pentadentate chelates with all binding atoms of the chelating agent being carbon atoms, denoted as CCCCC chelates. Having up to five metal-carbon bonds in the equatorial plane has not been previously observed in transition metal chemistry. Density functional theory calculations showed that the planar metallacycle has extended Craig-Möbius aromaticity arising from 12-center–12-electron dπ-pπ π-conjugation. These planar chelates have broad absorption in the ultraviolet-visible–near-infrared region and, thus, notable photothermal performance upon irradiation by an 808-nm laser, indicating that these chelates have potential applications in photothermal therapy. The combination of facile synthesis, high stability, and broad absorption of these complexes could make the polydentate carbon chain a novel building block in coordination chemistry.the National Basic Research Program of China (nos. 2012CB821600 and 2014CB744503) , the National Science Foundation of China (nos. 21332002, 81422023, 51273165, 21490573, and 21573179)

中国退化河口湿地生态恢复研究进展

湿地退化、恢复和重建是当前湿地科学领域的研究热点,也是中国湿地研究中的核心问题。作为一种典型的海岸湿地,河口湿地在围垦、水利工程建设和环境污染等多重因素的干扰下,面临着自然来水减少、水盐失衡、植被退化、生境质量下降等多种威胁。介绍了当前中国河口湿地的分布情况以及四大主要河口湿地的退化现状,针对已经开展的河口退化湿地恢复的现状,总结了目前中国河口退化湿地恢复所面临的问题,并展望了今后河口退化湿地恢复研究的趋势:开展河口湿地生态系统演替与退化机制研究;发展河口湿地生态恢复技术;加强河口湿地生态恢复示范研究以及建立动态监测和管理系统