Evaluation of the schoolbooks used in the primary school system in the Czech Republic. Creation of a qualitative evaluation grid

TITLE: Evaluation of the schoolbooks used in the primary school system in the Czech Republic. Creation of a qualitative evaluation grid. AUTHOR:: Department: SUPERVISOR: ABSTRACT: KEYWORDS: Schoolbook, qualitative schoolbook grid, supplemental procedure, selection of schoolbooks, pupils, teachers, parents, educational triangulation.Evaluace kvality učebnic užívaných v rámci primárního školství v ČR. Vytvoření kvalitativního evaluačního rastru. Doktorand: Petr Šulc Pracoviště: Pedagogická fakulta UK Praha - katedra primární pedagogiky Školitel: doc. PaedDr. Radka Wildová, CSc. ABSTRAKT: Cílem této práce bylo vytvořit kvalitativní rastr, který by pomohl učitelům při kvalifikovaném výběru učebnic. V teoretické části jsme formulovali předpoklad, že kvalitu učebnic je nutné analyzovat z pohledu užitných vlastností, důležitých pro jednotlivé uživatele (žáky, rodiče, učitele, školu) s akcentací na jejich hierarchii. Náš výzkum však ukázal, že problém je mnohem komplexnější. Jednoduchý kvalitativní rastr, v praxi použitelný řadovými učiteli, nebylo možné sestavit. Efektivnější se ukázala varianta, která počítá s vypracováním kvalitativního rastru jako součásti vlastního doložkového řízení. Z tohoto důvodu jsme v závěru práce navrhli systémové změny, které by měly kvalitu učebnic zvýšit, jakož i zajistit jejich pravidelnou obměnu v rámci školského systému, tak aby byly stále aktuální, moderní, graficky i obsahově přehledné, aby jejich design odpovídal věku dítěte i současným designovým trendům. Změny směřují i ke zlevnění produkce učebnic i usnadnění jejich výběru učiteli. Zamýšleli jsme se také nad systémem doložkového řízení, tedy zda jej...Oddělení pro vědeckou činnostPedagogická fakultaFaculty of Educatio

DURABILITY OF CONCRETE WITH BINDER BASED ON SULFOCALCIC FLY ASH

This paper deals with the durability of concrete with binder based on sulfocalcic fly ash. At the beginning, in the theoretical part, there is a research on the frost resistance of concrete, its resistance to chemical thaw substances and measures to extend the durability of the concrete. There is also a part about sulfocalcic fluid fly ash and concrete. Practical part is devoted to individual input materials and experimental procedures. There is also described the methodology of the design of the individual mixtures and the results from the tests and their comparison

Coarse-grained modelling of supercoiled RNA

We study the behaviour of double-stranded RNA under twist and tension using oxRNA, a recently developed coarse-grained model of RNA. Introducing explicit salt-dependence into the model allows us to directly compare our results to data from recent single-molecule experiments. The model reproduces extension curves as a function of twist and stretching force, including the buckling transition and the behaviour of plectoneme structures. For negative supercoiling, we predict denaturation bubble formation in plectoneme end-loops, suggesting preferential plectoneme localisation in weak base sequences. OxRNA exhibits a positive twist-stretch coupling constant, in agreement with recent experimental observations.Comment: 8 pages + 5 pages Supplementary Materia

Hairygami: Analysis of DNA Nanostructures' Conformational Change Driven by Functionalizable Overhangs

DNA origami is a widely used method to construct nanostructures by self-assembling designed DNA strands. These structures are often used as "breadboards" for templated assembly of proteins, gold nanoparticles, aptamers, and other molecules, with applications ranging from therapeutics and diagnostics to plasmonics and photonics. Imaging these structures using AFM or TEM is not capable to capture their full conformation ensemble as they only show their structure flattened on a surface. However, certain conformations of the nanostructure can position guest molecules into distances unaccounted for in their intended design, thus leading to spurious interactions between guest molecules that are designed to be separated. Here, we use molecular dynamics simulations to capture conformational ensemble of 2D DNA origami tiles and show that introducing single-stranded overhangs, which are typically used for functionalization of the origami with guest molecules, induces a curvature of the tile structure in the bulk. We show that the shape deformation is of entropic origin, with implications for design of robust DNA origami breadboards as well as potential approach to modulate structure shape by introducing overhangs. We then verify experimentally that the overhangs introduce curvature into the DNA origami tiles

Learning the nonlinear interactions from particle trajectories

Nonlinear interaction of membrane proteins with cytoskeleton and membrane leads to non-Gaussian structure of their displacement probability distribution. We propose a novel statistical analysis technique for learning the characteristics of the nonlinear potential from the cumulants of the displacement distribution. The efficiency of the approach is demonstrated on the analysis of kurtosis of the displacement distribution of the particle traveling on a membrane in a cage-type potential. Results of numerical simulations are supported by analytical predictions. We show that the approach allows robust identification of the potential for the much lower temporal resolution compare with the mean square displacement analysis.Comment: 5 pages, 4 figure