Hypercalciuria in Postmenopausal Osteoporosis

Women aged between 35 to 75, termed as postmenopausal at least for one year, not smoking and not drinking alcohol, not using any medicine related with menopause and osteoporosis made up our patient and control groups. We investigated serum calcium, phosphorus, alkaline phosphatase, creatinine levels and urinary calcium level, calcium to creatinine ratio in post-menopausal women with osteoporosis (n = 25) and without osteoporosis (n =25). In our study hypercalciuria was found in 68% of women with osteoporosis and in 36% of women without osteoporosis. It was also found that there was a significant difference in calcium to creatinine ratio between the two groups (p<0,05). We also found that serum phosphorus level in women with osteoporosis was significantly higher than the other group (p<0,05). The results were compared with similar studies in literature

Comparison of Dual Energy X-Ray Absorptiometry and Quantitative Ultrasonography Measurements in Osteoporotic Patients - Original Investigation

Aim: Osteoporosis (OP) is a skelatal disease of bone fragility resulting from micro-architectural deteriotarion and decreased bone mass. There are many studies in literature that show high sensibility and specifity of quantitative ultrasonography (QUS). Recently many comparatives studies of QUS and dual energy X-ray absorbtiometry (DEXA) have been made. In this study we aimed to investigate correlation of QUS and DEXA measurments in 53 women with postmenopausal osteoporosis were enrolled in this study. Material and Method: Fifty three postmenopausal women with osteoporosis were studied: Ultrasound parameters were measured by the DTU-one imaging ultrasonometer in the calcaneus. BMD was assessed by dual-energy X-ray absorptiometry (DEXA) at the lumbar spine, femoral neck, and trochanter. QUS measurements of the postmenopausal women was compared with DEXA measurements. Results: There was a significant correlation between QUS T scores and DEXA L2-L4 T scores (r =0.463 p=0.000 p<0.005), there was a significant correlation between QUS Z scores and DEXA L2-L4 Z scores (r =0.589 p=0.000 p<0.005 ), there was a significant correlation between QUS T scores and DEXA femur neck T scores (r =0.463 p=0.000 p<0.005 ), there was a significant correlation between QUS Z scores and DEXA femur Z scores (r =0.418 p=0.000 p<0.005). Conclusion: Consequently QUS results were correlated with DEXA results in postmenopausal osteoporotic patients. (From the World of Osteoporosis 2008;14:26-8