Bilateral Tubal Ectopic Pregnancy After Assisted Reproduction Technique: A Case Report

Ectopic pregnancy is still an important cause of maternal mortality. Bilateral tubal ectopic pregnancy is very rare, and is usually the result of an assisted reproduction technique. We describe a case of early bilateral tubal pregnancy diagnosed by transvaginal ultrasonography after intracytoplasmic sperm injection (ICSI) and embryo transfer (ET)

Effect of Ovulation Induction on Ovarian Histologies in a Rat Model

OBJECTIVE: To examine the effect of human menopausal gonadotropin(HMG) and follitropinBeta (rFSH) on the ovarian histologies in a rat model. STUDY DESING:Thirty-nine female, one-year old rats were enrolled for the trial. They were divided into three groups. In the first group, 13 rats received, six cycles of ovulation induction with human menapausal gonadotropin.In the second group, 13 rats received six cycles of ovulation induction with folitropin beta the third study group consisted of 13 rats which received six cycles of saline intramuscularly. RESULT: The mean number of the cells that stained positive for Ki-67 was 42.3±20.6, 44.9±27.3and 42.5±24.8 in the folicles, respectively.The mean number of cells that stained positive for Ki-67 in epithelium was 0.15±0.42, 0.04±0.14,0.05±0.18, respectively. The mean dysplasiascore was 2.46±2.10, 1.69±13 and 1.62±1.89 in the ovarian epithelial cells respectively. CONCLUSION:Development of malignant lesion were not found in any of the rat ovaries after ovulation induction. As a result of this study, we found out that human menapausal gonodotropin and folitropin beta used in treatment of infertility, when administered for six cycles in accordence with the dosage determined, do not have the potential to develop neoplasia in rats

Effects of Spray Gel Compared with The Methods of Using Interceed Seprafilm and Ringer Lactate for The Prevention of The Postoperative Adhesions

OBJECTIVE: To compare the spray gel with the methods of using interceed, seprafilm or intraperitoneal lavage with ringer lactate, which are used to prevent the postoperative adhesions. STUDY DESIGN: The rats were randomly divided into 5 groups each including 10 rats. Laparatomy was performed via lower median incision. The first group (group 1) served as the control (nothing was given to prevent the adhesion). In group 2, 4 cc. Ringer lactate solution was instilled into the peritoneal cavity before abdominal closure. In group 3 Interceed (2 x 3 cm) was placed to the adhesion region. In the group 4 Seprafilm (2 x 3 cm) was used for to prevent adhesions. In the last group (group 5) spray gel was used 1 - 2 cc. to form 2 mm. thickness on the cauterized surface..Statistical evaluation was made using analysis of variance Kruskal - Wallis and Mann - Whitney U Tests and the results were accepted to be significant if the P<0.01. RESULTS: The postoperative average adhesion scores were found significantly decreased on the ringer lactate (p=0,00l), interceed (p=0,00l), seprafilm (p<0,001) and spray gel (p<0,001), groups compared to the control group.There were no statistical significant differences between the average adhesion scores of the groups which used spray gel: ringer lactate (p=0,473), interceed (P=0,888), and seprafilm (p= 1 ,000).(P>0,005). CONCLUSION: The effectiveness of the spray gel for the prevention of adhesion formation is found similar to the methods of ringer lactate, interceed and seprafilm