Mild encephalitis/encephalopathy with a reversible splenial lesion in children

PURPOSE:We aimed to present clinical and radiologic characteristics of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) in children.METHODS:Eight children (5 boys and 3 girls; median age, 5.9 years; age range, 8 months to 14.1 years) diagnosed with MERS between September 2015 and June 2017 were included in the study. We reviewed the patient’s data, including demographic characteristics, prodromal and neurologic symptoms, neurologic examination, magnetic resonance imaging and electroencephalography findings, laboratory findings, treatment, and prognosis.RESULTS:Prodromal symptoms were nausea and vomiting (n=6), diarrhea (n=6), and fever (n=3). Initial neurologic symptoms were seizures (n=4), delirious behavior (n=1), drowsiness (n=1), ataxia (n=1), transient blindness (n=2), abnormal speech (n=2), and headache (n=1). Two patients had a suspected infective agent: urinary tract infection caused by Escherichia coli and gastroenteritis caused by rotavirus. Seven patients had type I lesions, comprising characteristic symmetric ovoid (n=6) and band-shaped (n=1) T2-weighted hyperintense lesions at the spenium of corpus callosum, and one patient had type II lesion with additional symmetric posterior periventricular lesions. The lesions were isointense to mildly hypointense on T1-weighted imaging and did not show enhancement. All lesions displayed restricted diffusion. In all patients, neurologic symptoms completely normalized <48 hours from the onset of symptoms without any sequelae.CONCLUSION:MERS has characteristic imaging features and favorable outcome

Computed tomography findings of organizing pneumonia

Objective: In this study, we aimed to present computed tomography (CT) findings of 100 patients with histopathologically confirmed organizing pneumonia. Design: Retrospective study Setting: Ankara Atatürk Chest Diseases And Chest Surgery Training And Surgery Hospital, Ankara, Turkey Subjects: One hundred histopathologically confirmed organizing pneumonia patients between 2009 and 2013 admitted to our clinic. Intervention: A chest CT scan and the histopathological examination of the lung lesions of the patients were performed. Main outcome measure: The frequency and the types of CT findings of the patients with proven organizing pneumonia were examined. Results: Among 100 patients, 73 were male and 27 were female, and the mean age of the patients was 60±11 (range:19-90) years. Pulmonary consolidation was detected in 87 patients and ground-glass opacity was seen in 76 patients. Multiple nodules were seen in 20 patients while a solitary nodule was seen in 15 patients. Acinar nodular pattern was detected in 29 patients, micronodular pattern in 28 patients, bronchocentric pattern in 33 patients, perilobular pattern in 14 patients, progressive fibrotic pattern in 8 patients and reversed halo sign in 12 patients. Lymph node enlargement was seen in 80 patients. Conclusion: Computed tomography is very important for the diagnosis of organizing pneumonia which has various radiological findings. © 2022, Kuwait Medical Association. All rights reserved