The morphometric measurement of the brain stem in Turkish healthy subjects according to age and sex

Background: This paper determined the morphometric measurements of the brainstem including mesencephalon, pons and medulla using magnetic resonance imaging (MRI) in Turkish healthy population. Materials and methods: Two hundred sixty-three (263; 158 females and 105 males) subjects aged from 18 to 65 years were included in this study. The measurements were taken from subjects having brain MRI in the Radiology Department. Statistical analysis was done by SPSS 21.00 package programme. ANOVA test and χ2 test were used to determine the relation between measurements and age and sex groups. The p < 0.05 value was considered as significant. Results: The overall means and standard deviations of the measurements were: pons anteroposterior diameter, 15.41 ± 1.27 mm; pons vertical diameter, 22.02 ± 2.07 mm; mesencephalon anteroposterior diameter 9.39 ± 1.00 mm; mesencephalon vertical diameter, 15.20 ± 1.53 mm; distance between the interpeduncular fissure and aqueduct, 11.72 ± 1.58 mm; distance from cerebral peduncles to aqueduct, 13.64 ± 1.66 mm; anterior surface of the pons midway between the mesencephalon and medulla to the fourth ventricular floor, 21.62 ± 1.64 mm; the shortest anteroposterior diameter of the medulla at the pontomedullary junction, 13.46 ± 1.28 mm, and the shortest anteroposterior diameter of the medulla at the medullospinal junction, 10.24 ± 1.43 mm in females, respectively, whereas the corresponding values were 15.58 ± 1.53 mm; 22.64 ± 2.35 mm; 9.37 ± 1.66 mm; 15.64 ± 1.52 mm; 11.14 ± 1.31 mm; 13.01 ± 1.30 mm; 21.97 ± 1.65 mm;13.47 ± 1.19 mm; 9.91 ± 1.35 mm in males, respectively. There were significant differences in some parameters such as pons vertical diameter, mesencephalon vertical diameter, distance between the interpeduncular fissure and aqueduct, and distance between cerebral peduncles to aqueduct between sexes. Conclusions: The brainstem dimensions of healthy population provide important and useful knowledge in terms of comparison of abnormalities clinically. These data may be valuable for the representatives of clinical disciplines

The determination of the pituitary gland, optic chiasm, and intercavernous distance measurements in healthy subjects according to age and gender

Background: This paper was undertaken to determine the morphometry of pituitary gland diameter, pituitary gland height, intercavernous distance, optic chiasm diameter and optic chiasm height in skulls of Turkish population aged between 18 and 60 years. Materials and methods: It was a retrospective study in which 292 subjects were included 187 females and 105 males, ranging from 18 up to 60 years. Subjects underwent brain magnetic resonance imaging in the Radiology Department. Statistical analysis was performed with SPSS 21.00 programme. ANOVA test, χ2 test, and Pearson correlation analysis were used to determine the relation and significance between measurements and age group. The p < 0.05 value was considered as significant. Results: The groups were divided into five groups according to age. The overall means and standard deviations of the measurements were: pituitary gland width, 13.09 ± 1.99 mm; pituitary gland height, 4.91 ± 1.10 mm; intercavernous distance, 15.93 ± 3.05 mm; optic chiasm width, 12.82 ± 1.27 mm; and optic chiasm height, 2.80 ± 0.49 mm in females, respectively whereas, the same measurements were 12.96 ± 1.74 mm; 4.79 ± 0.95 mm; 16.08 ± 3.11 mm; 13.13 ± 1.37 mm; 2.86 ± 0.70 mm in males, respectively. Height of the pituitary gland reached a maximum in the age group of 18 to 20 years in both females and males and there was a decrease in the pituitary gland height in the subsequent age groups. Conclusions: Knowledge of the variation in the size of pituitary gland, intercavernous distance and optic chiasm is important to evaluate the dimensions of these structures for clinical and pathological processes