153 research outputs found

    Macronutrients contribution from beverages according to sex and age: fi ndings from the ANIBES Study in Spain

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    Abstract Methodologies and procedures used in dietary surveys have been widely developed with the aim of evaluating the nutritional status of a population. However, beverages are often either disregarded at national and international assessment of nutrients intake or poorly mentioned. Moreover, there is no standardized questionnaire developed as a research tool for the evaluation of beverages intake in the general population. Moreover, the contribution of different beverages to macronutrients intake is rarely provided. The latter in the context of a continuous expansion and innovation of the beverages market in Spain. Therefore, the main goal of the present study was to evaluate non-alcoholic and alcoholic beverages macronutrients contribution in the ANIBES study in Spain (9-75 years old). As expected, those contributed to dietary macronutrient intake mainly as total carbohydrates and sugar. The contribution to other macronutrients (proteins and lipids) by the beverage groups was of much less importance. For non-alcoholic beverages, contribution to carbohydrates was much higher in younger populations (children: 10.91 ± 9.49%, mean ± SD for boys and 9.46 ± 8.83% for girls; adolescents: 11.97 ± 11.26% for men and 13.77 ± 10.55% in women) than in adults: 9.01 ± 9.84% for men and 7.77 ± 8.73% in women. Finally, a much lower contribution was observed in the elderly: 4.22 ± 6.10% for men and 4.46 ± 6.56% for women. No sex differences, however, across all age groups were found. Results for sugar contribution showed a similar trend: children (23.14 ± 19.00% for boys and 19.77 ± 17.35% for girls); adolescents (28.13 ± 24.17% for men and 29.83 ± 21.82% in women); adults 20.42 ± 20.35% for men and 16.95 ± 17.76% in women, p ≤ 0.01; and elderly: 14.63% ± 9.97 for men and 9.33 ± 12.86% in women. The main contribution corresponded to sugared soft drinks, juices and nectars, more relevant and signifi cant in the younger populations. As for alcoholic beverages, the contribution of macronutrients to the total diet is low for carbohydrates and sugar. The main contribution of this group, as expected, is alcohol, being higher from low alcohol content beverages, and in men vs women (p ≤ 0.001)

    Universidad y colectivos vulnerables

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    El acceso y permanencia en la universidad sigue sin ofrecer, por el momento, las mismas oportunidades a todos los ciudadanos que están en condiciones de realizar estudios superiores. Razones económicas, culturales, sociales o de género castigan posibilidades de realización y de promoción personal y social. La utopía de una universidad más inclusiva sigue siendo, al respecto, un reto para estas instituciones. La presente aportación, complementaria a otras ya editadas anteriormente (http://accelera.uab.cat/documents_edo/biblio/) sobre la temática, recoge las aportaciones más significativas presentadas en el Congreso Universidad y Colectivos Vulnerables 2014, celebrado en Veracruz (México) el 29 y 30 de octubre de 2014. Promovido por el Proyecto ACCEDES (http://edo.uab.cat/accedes/), ha sido un espacio para presentar y debatir los resultados del mismo, así como una oportunidad para el encuentro con otros proyectos y experiencias significativas sobre la temática. Lo más destacable de la misma, es la huida que representa de aportaciones generales sobre la universidad inclusiva y la focalización que realiza en relación a propuestas concretas centradas en los colectivos más vulnerables que se pueden encontrar en las universidades: indígenas, mujeres, discapacitados, minorías, no habituales, estudiantes de zonas rurales, emigrantes y colectivos con un Índice de Desarrollo Humano (IDH) muy bajo. También la orientación práctica, al centrarse en estrategias, instrumentos y experiencias. Se trata, en síntesis, de apoyar el desarrollo de una universidad cuya misión y objetivos se orientan a promover la inclusión de todos los estudiantes y, especialmente, de aquellos que se encuentran en una situación de vulnerabilidad y que pueden poner en evidencia la capacidad o incapacidad del sistema universitario para lograr el equilibrio entre calidad y equidad. El proyecto ACCEDES, financiado por la Unión Europea, contribuye así a alcanzar sus propósitos vinculados al desarrollo de herramientas para el desarrollo organizacional de las instituciones de educación superior en la aplicación de las acciones de mejora en el acceso, excelencia académica y fase de egreso de colectivos vulnerables. Esperemos que su contenido sirva al propósito mencionado, contribuya a la promoción de la inclusión en la educación superior en Latinoamérica y ayude a encontrar el equilibro entre calidad y equidad en los sistemas universitarios

    Camelids in the south of the Iberian Peninsula in Roman and medieval times. Osteological evidence from the city of Cordoba (Spain)

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    This paper presents the results obtained concerning the possible presence of camelids in the city of Cordoba (Spain) in Roman and medieval times, after the review of all the faunal assemblages corresponding to these historical periods deposited in the Provincial Archaeological Museum of the city. This research has allowed the recovery and contextualization of nine dromedary bone remains corresponding to nine individuals, four of which have been dated by C. A stable isotope analysis has also been carried out which indicates the possible arrival of these animals from other provinces of the empire in Roman times and from North Africa in medieval times. Besides, we carried out a bibliographical update of all bone remains found in the Iberian Peninsula for the periods analyzed, concluding that the main use of them was for transporting and manufacturing different tools.This study have been funded through the Andalusian Regional Government’s I + D + i-FEDER Andalucía 2014-2020 program. C.A.M.E.L. Historical contextualization, Diet, Morphology, Genetic Study, and Lineage through the bone remains of camels recovered in archaeological sites in the southern Iberian Peninsula (Ref. 1380946-F) and Ministry of Science and Innovation of Spain through European Regional [SUMHAL, LIFEWATCH-2019-09-CSIC-13, POPE 2014-2020]. Both Dr. José A. Riquelme Cantal and Dr. Juan Manuel Garrido Anguita are the principal investigators leading the projects that have funded this research. Funding for open access charge: Universidad de Córdoba /CBUA

    Effect of salinity on DNA methylation and antioxidant phenolic compounds of wild watercress (Rorippa nasturtium aquaticum)

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    Epigenetic changes are involved in plant responses to stress. Cytosine methylation is one of the most important epigenetic changes, regulating gene expression. In this paper, the MSAP (methylation-sensitive amplification polymorphism) method was used to find out how the watercress (Rorippa nasturtium aquaticum) genome changed in response to 0, 60, 80, and 100 mM NaCl and how that affected phenylalanine ammonium lyase (PAL) activity, phenolic content, and antioxidant capacity. The results showed an inverse correlation between methylation levels and PAL activity and the contents of total phenolics and flavonoids, indicating salt stress-induced reprogramming of the methylation pattern of watercress, which has a negative effect on the synthesis of phenolics. The results revealed a significant decrease in phenolic contents and antioxidant activity under low and moderate salinity compared to control and an increase under strong salinity compared to moderate salinity. The findings of this study contribute to our understanding of the reprogramming of DNA methylation under salinity and its effect on watercress phenolic metabolism

    Helix aspersa (Stylommatophora: Helicidae) plaga emergente de la manzana (Malus Spp.) en Guerrero, Chihuahua

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    In Mexico the apple tree is one of the most important fruit-trees with high economical value. This tree is affected by several pests, one of them is the garden common snail (Helix aspersa). At the locality of Mesa Miñaca, Guerrero, Chihuahua, this snail feeds on apple leaves and also from its fruits. This behavior was observed since 2013 at this locality, and nowadays the causes of its emergence and dispersion remain unknown.El manzano es uno de los principales frutales de importancia económica para México. Se ve afectado por diferentes plagas, una de ellas el caracol común de jardín (Helix aspersa), que se alimenta de hojas y fruta en desarrollo en la localidad de Mesa Miñaca, Guerrero, Chihuahua, desde 2013. A la fecha se desconocen las causas que han favorecido la presencia y dispersión de la plaga en esa localidad

    Métodos de aprendizaje en Derecho Constitucional: red docente en Derechos y Libertades y Ciudadanía (Derecho de Etranjería/Inmigration Law) II

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    El presente trabajo es la continuación de la investigación docente sobre Derecho de Extranjería/Immigration Law iniciado en el Curso 2014-15. El marco constitucional es el hilo conductor en el aprendizaje en materia de extranjería. Se trata de la interacción entre las experiencias docentes de tres Universidades (Estados Unidos, España y Perú Colombia). El contenido de esta Memoria da cuenta de la segunda etapa en esta interacción en Red. Expone la experiencia de análisis de casos desde el derecho comparado y de los Informes jurídicos sobre la problemática actual de la inmigración en España

    Adaptación al bilingüismo del material docente de prácticas de Zoología

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    El objetivo principal de este proyecto de innovación docente es la adaptación al bilingüismo, concretamente al inglés, del material de prácticas (presenciales y virtuales) de la asignatura de Zoología del grado de Biología. Este objetivo se enmarca dentro del actual proceso de internacionalización de la UGR, que en el caso concreto del grado de Biología se ha iniciado el curso académico 2021/2022 con algunas asignaturas impartidas en inglés. Aunque el bilingüismo en la asignatura de Zoología se ha retrasado hasta el curso 2022/2023.Universidad de Granad

    Confronting the challenge: a regional perspective by the Latin American pediatric infectious diseases society (SLIPE) expert group on respiratory syncytial virus—tackling the burden of disease and implementing preventive solutions

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    Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infections in children around the world. The post-pandemic era has resulted in a notable increase in reported cases of RSV infections, co-circulation of other respiratory viruses, shifts in epidemiology, altered respiratory season timing, and increased healthcare demand. Low- and middle-income countries are responsible for the highest burden of RSV disease, contributing significantly to health expenses during respiratory seasons and RSV-associated mortality in children. Until recently, supportive measures were the only intervention to treat or prevent RSV-infection, since preventive strategies like palivizumab are limited for high-risk populations. Advances in new available strategies, such as long-acting monoclonal antibodies during the neonatal period and vaccination of pregnant women, are now a reality. As the Regional Expert Group of the Latin American Pediatric Infectious Diseases Society (SLIPE), we sought to evaluate the burden of RSV infection in Latin America and the Caribbean (LAC) region, analyze current strategies to prevent RSV infection in children, and provide recommendations for implementing new strategies for preventing RSV infection in children in LAC region

    Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis.

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    Progressive hepatic damage and fibrosis are major features of chronic liver diseases of different etiology, yet the underlying molecular mechanisms remain to be fully defined. N-RAS, a member of the RAS family of small guanine nucleotide-binding proteins also encompassing the highly homologous H-RAS and K-RAS isoforms, was previously reported to modulate cell death and renal fibrosis; however, its role in liver damage and fibrogenesis remains unknown. Here, we approached this question by using N-RAS deficient (N-RAS-/-) mice and two experimental models of liver injury and fibrosis, namely carbon tetrachloride (CCl4) intoxication and bile duct ligation (BDL). In wild-type (N-RAS+/+) mice both hepatotoxic procedures augmented N-RAS expression in the liver. Compared to N-RAS+/+ counterparts, N-RAS-/- mice subjected to either CCl4 or BDL showed exacerbated liver injury and fibrosis, which was associated with enhanced hepatic stellate cell (HSC) activation and leukocyte infiltration in the damaged liver. At the molecular level, after CCl4 or BDL, N-RAS-/- livers exhibited augmented expression of necroptotic death markers along with JNK1/2 hyperactivation. In line with this, N-RAS ablation in a human hepatocytic cell line resulted in enhanced activation of JNK and necroptosis mediators in response to cell death stimuli. Of note, loss of hepatic N-RAS expression was characteristic of chronic liver disease patients with fibrosis. Collectively, our study unveils a novel role for N-RAS as a negative controller of the progression of liver injury and fibrogenesis, by critically downregulating signaling pathways leading to hepatocyte necroptosis. Furthermore, it suggests that N-RAS may be of potential clinical value as prognostic biomarker of progressive fibrotic liver damage, or as a novel therapeutic target for the treatment of chronic liver disease

    Effect of viral storm in patients admitted to intensive care units with severe COVID-19 in Spain: a multicentre, prospective, cohort study

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    Background: The contribution of the virus to the pathogenesis of severe COVID-19 is still unclear. We aimed to evaluate associations between viral RNA load in plasma and host response, complications, and deaths in critically ill patients with COVID-19. Methods: We did a prospective cohort study across 23 hospitals in Spain. We included patients aged 18 years or older with laboratory-confirmed SARS-CoV-2 infection who were admitted to an intensive care unit between March 16, 2020, and Feb 27, 2021. RNA of the SARS-CoV-2 nucleocapsid region 1 (N1) was quantified in plasma samples collected from patients in the first 48 h following admission, using digital PCR. Patients were grouped on the basis of N1 quantity: VIR-N1-Zero ([removed]2747 N1 copies per mL). The primary outcome was all-cause death within 90 days after admission. We evaluated odds ratios (ORs) for the primary outcome between groups using a logistic regression analysis. Findings: 1068 patients met the inclusion criteria, of whom 117 had insufficient plasma samples and 115 had key information missing. 836 patients were included in the analysis, of whom 403 (48%) were in the VIR-N1-Low group, 283 (34%) were in the VIR-N1-Storm group, and 150 (18%) were in the VIR-N1-Zero group. Overall, patients in the VIR-N1-Storm group had the most severe disease: 266 (94%) of 283 patients received invasive mechanical ventilation (IMV), 116 (41%) developed acute kidney injury, 180 (65%) had secondary infections, and 148 (52%) died within 90 days. Patients in the VIR-N1-Zero group had the least severe disease: 81 (54%) of 150 received IMV, 34 (23%) developed acute kidney injury, 47 (32%) had secondary infections, and 26 (17%) died within 90 days (OR for death 0·30, 95% CI 0·16–0·55; p<0·0001, compared with the VIR-N1-Storm group). 106 (26%) of 403 patients in the VIR-N1-Low group died within 90 days (OR for death 0·39, 95% CI 0·26–0·57; p[removed]11 página
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