Preparation of asymmetric polyhydroxybutyrate/chitosan composite membrane for guided bone regeneration

[[abstract]]In this study, an asymmetric composite membrane composed of a porous chitosan layer and a dense polyhydroxybutyrate (PHB) layer was prepared, and its mechanical properties as well as cellular compatibility were evaluated. First, the PHB dense layer with a thickness of ca. 32 m was obtained by direct oven-drying. After being treated with plasma to produce free radicals on the surface and subsequently graft polymerized with poly(acrylic acid), the PHB was immersed in the CS solution where the CS chains could be chemically bonded to the PHB surface via carbodiimide activation. After lyophilization, an asymmetric PHB/CS composite membrane was obtained. Compared to the porous CS membrane, the composite membrane had higher tensile mechanical properties. In addition, the fibroblast cells (L929 and HGF) and human osteoblast cells (hFOB1.19) were cultured on both sides of the composite membrane. All the cells could proliferate very well indicating that both PHB and CS layers were cellular compatible. Yet, the PHB dense layer could prohibit the fibroblast cells to penetrate through the membrane. Thus, the asymmetric composite membrane can be use as a potential barrier membrane for guided bone regeneration in periodontal tissue engineering.[[sponsorship]]Taiwan Polymer Society[[conferencetype]]國際[[conferencedate]]20131117~20131122[[booktype]]電子版[[iscallforpapers]]Y[[conferencelocation]]Kaohsiung, Taiwa

Preparation and properties of dual-curable epoxyacrylate composites filled with different functionalized silica spheres

[[abstract]]In this study, uniform-sized silica spheres were first synthesized by sol-gel reaction under a basic environment and their surfaces were modified to possess different functional groups including vinyl, epoxide and amino groups by reaction with 3-methacryloxypropyl trimethoxy silane (MPTMS), vinyl triethoxysilane (VTEOS), 3-glycidoxy propyltrimethoxy silane (GPTMS) and 3-Aminopropyl trimethoxysilane (APTMS). The functionalized silica spheres were characterized by FTIR, 29Si and 13C solid-NMR and SEM. These silica spheres with size ranging from 150~250 nm were then added to the pre-synthesized difunctional epoxyacrylate resin with one epoxide end group and one vinyl terminal groups. After photo- and thermal cure, mechanical properties and fracture toughness were measured to elaborate the effects of different functionalized silica spheres on the properties of epoxyacrylate-silica composites. Tensile mechanical properties including initial modulus, ultimate tensile strength and elongation at break, and also the fracture toughness of the epoxyacrylate-silica composite were all increased with increasing the amount of modified silica spheres. The increase of fracture toughness was due to the crack deflection and particle-matrix debonding as evidenced by SEM pictures on the fracture surface. Among these composites, the one filled with the MPTMS-modified silica had the best tensile mechanical properties and fracture toughness.[[sponsorship]]Polymer Processing Society[[conferencetype]]國際[[conferencedate]]20130715~20130719[[booktype]]電子版[[iscallforpapers]]Y[[conferencelocation]]Nuremberg, German

生物可分解聚乳酸複合材料系統的製備及其放線菌分解動力模型

[[sponsorship]]東海大學[[conferencetype]]國內[[conferencedate]]20140110~20140111[[iscallforpapers]]Y[[conferencelocation]]台中, 台

The Synthesis of Calcium Phosphate by Reverse Emulsion Method and Its Use for the Preparation of Chitosan Composite Membranes

[[conferencetype]]國際[[conferencedate]]20101115~20101118[[booktype]]電子版[[iscallforpapers]]Y[[conferencelocation]]Taipei, Taiwa

光熱硬化型氧化石墨烯/環氧丙烯酸酯樹脂複合材料製備及其性質

[[sponsorship]]東海大學[[conferencetype]]國內[[conferencedate]]20140110~20140111[[iscallforpapers]]Y[[conferencelocation]]台中, 台

Fracture Behavior of Epoxyacrylate Composites with Surface-Modified Silica Spheres

[[conferencetype]]國際[[conferencedate]]20101115~20101118[[booktype]]紙本[[iscallforpapers]]Y[[conferencelocation]]Taipei, Taiwa

Intracellular hydrogen peroxide generation by chitosan-based bioreducible nanoparticles

[[sponsorship]]Japanese Society for Chitin and Chitosan[[conferencetype]]國際[[conferencedate]]20131004~20131008[[booktype]]電子版[[iscallforpapers]]Y[[conferencelocation]]Yonago, Japa

Thermal properties and flammability of polylactide/aluminum trihydrate composites with addition of organoclay and carbon fiber

ly 15-19, 2013, p. 123.[[sponsorship]]Polymer Processing Society[[cooperationtype]]國外[[conferencetype]]國際[[conferencedate]]20130715~20130719[[booktype]]電子版[[iscallforpapers]]Y[[conferencelocation]]Nuremberg, German