Variable convalescence and therapy after cadaveric renal transplantation under cyclosporin A and steroids

The postoperative convalescence period was analyzed for 42 consecutive patients who had cadaveric renal transplantation under therapy with cyclosporin A and steroids. Twenty-two of the patients underwent transplantation for the first time, and the other 20 had retransplantation. None of the recipients has died. With follow-up period of two to eight months, the survival rate of grafts is 96 per cent after first transplantation and 85 per cent after retransplantation. Immunosuppression with a standard regimen was used for all patients at the outset. Early convalescence was highly variable, often necessitating adjustments of cyclosporin A and steroid dosage to accommodate the possibilities of rejection or cyclosporin A nephrotoxicity, or both, simultaneously. Management problems were more frequent and complex in patients undergoing retransplantation. From the results, a classification of convalescence patterns was evolved, with recommendations about how standardized initial therapy should be adjusted if the renal graft does not function promptly or deteriorates later

Systemic hypertension in cats with acute kidney injury

Retrospective study of cats presenting to the Queen Mother Hospital for Animals, Royal Veterinary College with acute kidney injury between 2007 and 2015. Systolic blood pressure was measured using Doppler sphygmomanometry and systemic hypertension was defined pressures ê150 mmHg. Median systolic blood pressure measurement, grade of acute kidney injury (as defined by the International Renal Interest Society), serum creatinine on admission, anuria or oliguria, length of hospitalisation, survival to discharge and six‐month survival were all recorded

Wars, disasters and kidneys

This paper summarizes the impact that wars had on the history of nephrology, both worldwide and in the Ghent Medical Faculty notably on the definition, research and clinical aspects of acute kidney injury. The paper briefly describes the role of 'trench nephritis' as observed both during World War I and II, supporting the hypothesis that many of the clinical cases could have been due to Hantavirus nephropathy. The lessons learned from the experience with crush syndrome first observed in World War II and subsequently investigated over many decades form the basis for the creation of the Renal Disaster Relief Task Force of the International Society of Nephrology. Over the last 15 years, this Task Force has successfully intervened both in the prevention and management of crush syndrome in numerous disaster situations like major earthquakes

Surgical Treatment of Anuria

This article is written in detail concerning with the indication and treatment for the following 5 groups of anuria 1. Prerenal anuria . T h e cause is the disorder of circulation, metabolism, internal secretion or innervation of the splanchinic nerve. This group is easily cured with novocainization. 2. Renal anuria : Disfunction of the kidney is usually caused by inflammation or tumor. This group is treated with pelvic lavage, decapsulation, partial nephrectomy or peritoneal lavage. 3. Post r e nal anuria : When the urinary tract is occluded by stone or tumor, diagnosis is easy. These causes are exterminated with several popular surgical procedures. Plasty of the urinary tract, however, is necessary as secondary operation. 4. Arenal anuria :Nephrectomized patients are apt to suffer from the diseases of the contralateral kidney. In such a case, surgical application, such as homotransplantation of the kidney or use of a permanent artificial kidney, must be performed without hesitation while the affected kidney is still in the reversible condition. 5. Reflex anuria This is categorized in the prerenal an u ria. Surgeon may often have a experience of this disorder after a major operation