1 research outputs found
A Codon Frequency Obfuscation Heuristic for Raw Genomic Data Privacy
Genomic data provides clinical researchers with vast opportunities to study
various patient ailments. Yet the same data contains revealing information,
some of which a patient might want to remain concealed. The question then
arises: how can an entity transact in full DNA data while concealing certain
sensitive pieces of information in the genome sequence, and maintain DNA data
utility? As a response to this question, we propose a codon frequency
obfuscation heuristic, in which a redistribution of codon frequency values with
highly expressed genes is done in the same amino acid group, generating an
obfuscated DNA sequence. Our preliminary results show that it might be possible
to publish an obfuscated DNA sequence with a desired level of similarity
(utility) to the original DNA sequence.Comment: 8 Pages, 15 Figure