3,114 research outputs found
Nineteen Figures and Counting: Contextualization and Conservation Treatment of a Jacob Spoel Painting
This study focuses on the research, technical analysis, and treatment of an 1852 Jacob Spoel painting (Untitled, acc.62.28, 80cm H x 105cm W x 1.75cm D) owned by the Memorial Art Gallery and described as a ‘family gathering.’ When received by the department, the painting was not in a fit state for display; it was not structurally sound and had a disfiguring varnish reducing the readability of the composition. Technical research, multimodal imaging, radiography, and instrumental analysis, including x-ray fluorescence spectroscopy, Raman spectroscopy, cross-sectional analysis, and Fourier transform infrared spectroscopy, were carried out to understand the materials and techniques used by the artist. Results played a part in shaping the treatment strategy, and the painting was successfully stabilized and returned to a suitable condition for exhibition
2023-2024 Catalog
The 2023-2024 Governors State University Undergraduate and Graduate Catalog is a comprehensive listing of current information regarding:Degree RequirementsCourse OfferingsUndergraduate and Graduate Rules and Regulation
Towards Reliable and Accurate Global Structure-from-Motion
Reconstruction of objects or scenes from sparse point detections across multiple views is one of the most tackled problems in computer vision. Given the coordinates of 2D points tracked in multiple images, the problem consists of estimating the corresponding 3D points and cameras\u27 calibrations (intrinsic and pose), and can be solved by minimizing reprojection errors using bundle adjustment. However, given bundle adjustment\u27s nonlinear objective function and iterative nature, a good starting guess is required to converge to global minima. Global and Incremental Structure-from-Motion methods appear as ways to provide good initializations to bundle adjustment, each with different properties. While Global Structure-from-Motion has been shown to result in more accurate reconstructions compared to Incremental Structure-from-Motion, the latter has better scalability by starting with a small subset of images and sequentially adding new views, allowing reconstruction of sequences with millions of images. Additionally, both Global and Incremental Structure-from-Motion methods rely on accurate models of the scene or object, and under noisy conditions or high model uncertainty might result in poor initializations for bundle adjustment. Recently pOSE, a class of matrix factorization methods, has been proposed as an alternative to conventional Global SfM methods. These methods use VarPro - a second-order optimization method - to minimize a linear combination of an approximation of reprojection errors and a regularization term based on an affine camera model, and have been shown to converge to global minima with a high rate even when starting from random camera calibration estimations.This thesis aims at improving the reliability and accuracy of global SfM through different approaches. First, by studying conditions for global optimality of point set registration, a point cloud averaging method that can be used when (incomplete) 3D point clouds of the same scene in different coordinate systems are available. Second, by extending pOSE methods to different Structure-from-Motion problem instances, such as Non-Rigid SfM or radial distortion invariant SfM. Third and finally, by replacing the regularization term of pOSE methods with an exponential regularization on the projective depth of the 3D point estimations, resulting in a loss that achieves reconstructions with accuracy close to bundle adjustment
Analytical validation of innovative magneto-inertial outcomes: a controlled environment study.
peer reviewe
Management of socio-economic transformations of business processes: current realities, global challenges, forecast scenarios and development prospects
The authors of the scientific monograph have come to the conclusion that мanagement of socio-economic transformations of business processes requires the use of mechanisms to support of entrepreneurship, sectors of the national economy, the financial system, and critical infrastructure. Basic research focuses on assessment the state of social service provision, analysing economic security, implementing innovation and introducing digital technologies. The research results have been implemented in the different models of costing, credit risk and capital management, tax control, use of artificial intelligence and blockchain. The results of the study can be used in the developing of policies, programmes and strategies for economic security, development of the agricultural sector, transformation of industrial policy, implementation of employment policy in decision-making at the level of ministries and agencies that regulate the management of socio-economic and European integration processes. The results can also be used by students and young scientists in the educational process and conducting scientific research on global challenges and creation scenarios for the development of socio-economic processes
Biomaterials for Bone Tissue Engineering 2020
This book presents recent advances in the field of bone tissue engineering, including molecular insights, innovative biomaterials with regenerative properties (e.g., osteoinduction and osteoconduction), and physical stimuli to enhance bone regeneration
Development of Quantitative Bone SPECT Analysis Methods for Metastatic Bone Disease
Prostate cancer is one of the most prevalent types of cancer in males in the United States. Bone is a common site of metastases for metastatic prostate cancer. However, bone metastases are often considered “unmeasurable” using standard anatomic imaging and the RECIST 1.1 criteria. As a result, response to therapy is often suboptimally evaluated by visual interpretation of planar bone scintigraphy with response criteria related to the presence or absence of new lesions. With the commercial availability of quantitative single-photon emission computed tomography (SPECT) methods, it is now feasible to establish quantitative metrics of therapy response by skeletal metastases. Quantitative bone SPECT (QBSPECT) may provide the ability to estimate bone lesion uptake, volume, and the number of lesions more accurately than planar imaging. However, the accuracy of activity quantification in QBSPECT relies heavily on the precision with which bone metastases and bone structures are delineated. In this research, we aim at developing automated image segmentation methods for fast and accurate delineation of bone and bone metastases in QBSPECT. To begin, we developed registration methods to generate a dataset of realistic and anatomically-varying computerized phantoms for use in QBSPECT simulations. Using these simulations, we develop supervised computer-automated segmentation methods to minimize intra- and inter-observer variations in delineating bone metastases. This project provides accurate segmentation techniques for QBSPECT and paves the way for the development of QBSPECT methods for assessing bone metastases’ therapy response
Recommended from our members
Analysis of bendable osteochondral allograft treatment and investigations of articular cartilage wear mechanics
Osteoarthritis is a highly prevalent, debilitating disease characterized by the wear and degradation of articular cartilage. While many surgical interventions exist, few are consistently effective and those that are effective are not necessarily suitable for all patients. The objective of this dissertation is to improve patient care through the development of a new surgical technique and through basic science studies which seek to better understand articular cartilage wear initiation. Four studies, which address this objective are summarized below.
Osteochondral allograft transplantation provides a safe and effective treatment option for large cartilage defects, but its use is limited partly due to the difficulty of matching articular surface curvature between donor and recipient. We hypothesize that bendable osteochondral allografts may provide better curvature matching for patella transplants in the patellofemoral joint. The finite element study presented in Chapter 2 investigates patellofemoral joint congruence for unbent and bendable osteochondral allografts, at various flexion angles. Finite element models were created for 12 femur-patella osteochondral allograft pairings. Two grooves were cut into the bony substrate of each allograft, allowing the articular layer to bend. Patellofemoral joints with either unbent (OCA) or permanently bent (BOCA) allografts were articulated from 40 to 70 degrees flexion and contact area was calculated. OCAs and BOCAs were then shifted 6 mm distally toward the tibia (S-OCA, S-BOCA) to investigate the influence of proximal-distal alignment on congruence. On average, no significant difference in contact area was found between native patellofemoral joints and either OCAs or BOCAs (p > 0.25), indicating that both types of allografts restored native congruence. This result provides biomechanical support in favor of an emerging surgical procedure. S-BOCAs resulted in a significant increase in contact area relative to the remaining groups (p < 0.02). The fact that bendable osteochondral allografts produced equally good results implies that these bendable allografts may prove useful in future surgical procedures, with the possibility of transplanting them with a small distal shift. Surgeons who are reluctant to use osteochondral allografts for resurfacing patellae based on curvature matching capabilities may be more amenable to adopting bendable osteochondral allografts.
The recent development of bendable osteochondral allografts provides the potential for improved osteoarthritis treatment for joints whose current treatment is unsatisfactory. One such joint is the carpometacarpal joint in the thumb. While the current standard of care for carpometacarpal osteoarthritis, ligament reconstruction and tendon interposition, can reduce pain in the joint, it does not restore full joint function and mobility. A proposed alternative includes using an osteochondral allograft harvested from the femoral trochlea in a donor knee, machining grooves in the bone to allow the allograft to bend, and replacing the trapezium with this bent osteochondral allograft [1,2]. Chapter 3 of this dissertation discusses adjustments to the original design of the bendable allograft and the design of a custom surgical tool to perform the proposed surgery. Specification changes of the allograft included an overall size reduction in order to better fit within the carpometacarpal joint, minimum bone thickness requirements to avoid bone cracking during the surgical procedure, and a reduction from three grooves to two grooves, which provided sufficient bending yet avoided fracture of the allograft. The surgical tool was designed to be a custom forceps device, whose primary features included (1) jaws with an angled face to match the angle of allograft bending and (2) insertion holes for the Kirschner wire and compression screws used to anchor the allograft in the bent position. These customizations allow the tool to be used to bend the allograft, fix it in the bent configuration, and place the allograft in its proper position in the hand during anchoring of the bent allograft to the native trapezium.
The final two studies presented in this dissertation focus on furthering our current understanding of wear and structure-function relationships of articular cartilage. We hypothesize that cartilage wears due to fatigue failure in reciprocating compression instead of reciprocating friction. Chapter 4 compares reciprocating sliding of immature bovine articular cartilage against glass in two testing configurations: (1) a stationary contact area configuration (SCA), which results in static compression, interstitial fluid depressurization and increasing friction coefficient during reciprocating sliding, and (2) a migrating contact area configuration (MCA), which maintains fluid pressurization and low friction while producing reciprocating compressive loading during reciprocating sliding. Contact stress, sliding duration, and sliding distance were controlled to be similar between test groups. SCA tests exhibited an average friction coefficient of μ=0.084±0.032, while MCA tests exhibited a lower average friction coefficient of μ=0.020±0.008 (p<10^(-4)).
Despite the lower friction, MCA cartilage samples exhibited clear surface damage with a significantly greater average surface deviation from a fitted plane after wear testing (R_q=0.125±0.095 mm) than cartilage samples slid in a SCA configuration (R_q=0.044±0.017 mm, p=0.002), which showed minimal signs of wear. Polarized light microscopy confirmed that delamination damage occurred between the superficial and middle zones of the articular cartilage in MCA samples. The greatest wear was observed in the group with lowest friction coefficient, subjected to cyclical instead of static compression, implying that friction is not the primary driver of cartilage wear. Delamination between superficial and middle zones imply the main mode of wear is fatigue failure under cyclical compression, not fatigue or abrasion due to reciprocating frictional sliding.
The final study of this dissertation, presented in Chapter 5, investigates the importance of collagen fibril distribution in articular cartilage computational models. Finite element models were created to approximate a bovine humeral head and replicate previous experimental loading conditions [3]. Five different finite element analyses were run, each using a different fibril distribution model. Three of the models used two, four, or eight discrete fibril bundles, while two models used continuous fibril distributions with either isotropic or depth-dependent ellipsoidal distributions.
Two primary findings arose from this investigation. The first was the discovery that as the fibril distribution became more isotropic, the strain throughout the tissue decreased, even though the contact area between the articular surface and rigid platen remained relatively equal across distribution models. This suggests that computational models which approximate the collagen fibrils with an isotropic distribution may be underestimating the strain through the depth of the tissue. The second primary finding was that in the discrete distribution model with two fibril bundles, which followed the classically described Benninghoff structure [4], the greatest magnitude of shear strain during compressive loading was observed in the middle zone. However, the highest magnitude of shear strain observed in the isotropic fibril distribution model occurred in the deep zone near the subchondral surface. The observed results suggest that the type of fibril distribution used to model collagen in articular cartilage plays a role in depth-dependent strain magnitude and strain distribution
- …