Information Integration - the process of integration, evolution and versioning

At present, many information sources are available wherever you are. Most of the time, the information needed is spread across several of those information sources. Gathering this information is a tedious and time consuming job. Automating this process would assist the user in its task. Integration of the information sources provides a global information source with all information needed present. All of these information sources also change over time. With each change of the information source, the schema of this source can be changed as well. The data contained in the information source, however, cannot be changed every time, due to the huge amount of data that would have to be converted in order to conform to the most recent schema.\ud In this report we describe the current methods to information integration, evolution and versioning. We distinguish between integration of schemas and integration of the actual data. We also show some key issues when integrating XML data sources

Prediction of Metabolic Pathways Involvement in Prokaryotic UniProtKB Data by Association Rule Mining

The widening gap between known proteins and their functions has encouraged the development of methods to automatically infer annotations. Automatic functional annotation of proteins is expected to meet the conflicting requirements of maximizing annotation coverage, while minimizing erroneous functional assignments. This trade-off imposes a great challenge in designing intelligent systems to tackle the problem of automatic protein annotation. In this work, we present a system that utilizes rule mining techniques to predict metabolic pathways in prokaryotes. The resulting knowledge represents predictive models that assign pathway involvement to UniProtKB entries. We carried out an evaluation study of our system performance using cross-validation technique. We found that it achieved very promising results in pathway identification with an F1-measure of 0.982 and an AUC of 0.987. Our prediction models were then successfully applied to 6.2 million UniProtKB/TrEMBL reference proteome entries of prokaryotes. As a result, 663,724 entries were covered, where 436,510 of them lacked any previous pathway annotations

GXQuery: Extending XQuery for Querying Graph-structured XML Data

XML data can be naturally modeled as a graph. Existing query languages to XML can only express queries of matching XML document with a tree-structured schema with structural and value constraints without the consideration of graph features. The ability of such query languages cannot satisfy various requirements of querying graph-structured XML data. In this paper, GXQuery is presented as an extension of XQuery, an XML query language recommended byW3C, to express more flexible query on graph-structured XML. GXQuery expressions can match XML documentwith graph-structured schema with not only structural and value constraints, but also topological constraints