Analysis of Different Filters for Image Despeckling : A Review

Digital image acquisition and processing in clinical diagnosis plays a significant part. Medical images at the time of acquisition can be corrupted via noise. Removal of this noise from images is a challenging problem. The presence of signal dependent noise is referred as speckle which degrades the actual quality of an image. Considering, several techniques have been developed focused on speckle noise reduction. The primary purpose of these techniques was to improve visualization of an image followed by preprocessing step for segmentation, feature extraction and registration. The scope of this paper is to provide an overview of despeckling techniques

Evaluation of Digital Speckle Filters for Ultrasound Images

Ultrasound (US) images are inherently corrupted by speckle noise causing inaccuracy of medical diagnosis using this technique. Hence, numerous despeckling filters are used to denoise US images. However most of the despeckling techniques cause blurring to the US images. In this work, four filters namely Lee, Wavelet Linear Minimum Mean Square Error (LMMSE), Speckle-reduction Anisotropic Diffusion (SRAD) and Non-local-means (NLM) filters are evaluated in terms of their ability in noise removal and capability to preserve the image contrast. This is done through calculating four performance metrics Peak Signal to Noise Ratio (PSNR), Ultrasound Despeckling Assessment Index (USDSAI), Normalized Variance and Mean Preservation. The experiments were conducted on three different types of images which is simulated noise images, computer generated image and real US images. The evaluation in terms of PSNR, USDSAI, Normalized Variance and Mean Preservation shows that NLM filter is the best filter in all scenarios considering both speckle noise suppression and image restoration however with quite slow processing time. It may not be the best option of filter if speed is the priority during the image processing. Wavelet LMMSE filter is the next best performing filter after NLM filter with faster speed

Evaluation of Digital Speckle Filters for Ultrasound Images

Ultrasound (US) images are inherently corrupted by speckle noise causing inaccuracy of medical diagnosis using this technique. Hence, numerous despeckling filters are used to denoise US images. However most of the despeckling techniques cause blurring to the US images. In this work, four filters namely Lee, Wavelet Linear Minimum Mean Square Error (LMMSE), Speckle-reduction Anisotropic Diffusion (SRAD) and Non-local-means (NLM) filters are evaluated in terms of their ability in noise removal and capability to preserve the image contrast. This is done through calculating four performance metrics Peak Signal to Noise Ratio (PSNR), Ultrasound Despeckling Assessment Index (USDSAI), Normalized Variance and Mean Preservation. The experiments were conducted on three different types of images which is simulated noise images, computer generated image and real US images. The evaluation in terms of PSNR, USDSAI, Normalized Variance and Mean Preservation shows that NLM filter is the best filter in all scenarios considering both speckle noise suppression and image restoration however with quite slow processing time. It may not be the best option of filter if speed is the priority during the image processing. Wavelet LMMSE filter is the next best performing filter after NLM filter with faster speed

Ultrasound Imaging Innovations for Visualization and Quantification of Vascular Biomarkers

The existence of plaque in the carotid arteries, which provide circulation to the brain, is a known risk for stroke and dementia. Alas, this risk factor is present in 25% of the adult population. Proper assessment of carotid plaque may play a significant role in preventing and managing stroke and dementia. However, current plaque assessment routines have known limitations in assessing individual risk for future cardiovascular events. There is a practical need to derive new vascular biomarkers that are indicative of cardiovascular risk based on hemodynamic information. Nonetheless, the derivation of these biomarkers is not a trivial technical task because none of the existing clinical imaging modalities have adequate time resolution to track the spatiotemporal dynamics of arterial blood flow that is pulsatile in nature. The goal of this dissertation is to devise a new ultrasound imaging framework to measure vascular biomarkers related to turbulent flow, intra-plaque microvasculature, and blood flow rate. Central to the proposed framework is the use of high frame rate ultrasound (HiFRUS) imaging principles to track hemodynamic events at fine temporal resolution (through using frame rates of greater than 1000 frames per second). The existence of turbulent flow and intra-plaque microvessels, as well as anomalous blood flow rate, are all closely related to the formation and progression of carotid plaque. Therefore, quantifying these biomarkers can improve the identification of individuals with carotid plaque who are at risk for future cardiovascular events. To facilitate the testing and the implementation of the proposed imaging algorithms, this dissertation has included the development of new experimental models (in the form of flow phantoms) and a new HiFRUS imaging platform with live scanning and on-demand playback functionalities. Pilot studies were also carried out on rats and human volunteers. Results generally demonstrated the real-time performance and the practical efficacy of the proposed algorithms. The proposed ultrasound imaging framework is expected to improve carotid plaque risk classification and, in turn, facilitate timely identification of at-risk individuals. It may also be used to derive new insights on carotid plaque formation and progression to aid disease management and the development of personalized treatment strategies