101,473 research outputs found
Bayesian Best-Arm Identification for Selecting Influenza Mitigation Strategies
Pandemic influenza has the epidemic potential to kill millions of people.
While various preventive measures exist (i.a., vaccination and school
closures), deciding on strategies that lead to their most effective and
efficient use remains challenging. To this end, individual-based
epidemiological models are essential to assist decision makers in determining
the best strategy to curb epidemic spread. However, individual-based models are
computationally intensive and it is therefore pivotal to identify the optimal
strategy using a minimal amount of model evaluations. Additionally, as
epidemiological modeling experiments need to be planned, a computational budget
needs to be specified a priori. Consequently, we present a new sampling
technique to optimize the evaluation of preventive strategies using fixed
budget best-arm identification algorithms. We use epidemiological modeling
theory to derive knowledge about the reward distribution which we exploit using
Bayesian best-arm identification algorithms (i.e., Top-two Thompson sampling
and BayesGap). We evaluate these algorithms in a realistic experimental setting
and demonstrate that it is possible to identify the optimal strategy using only
a limited number of model evaluations, i.e., 2-to-3 times faster compared to
the uniform sampling method, the predominant technique used for epidemiological
decision making in the literature. Finally, we contribute and evaluate a
statistic for Top-two Thompson sampling to inform the decision makers about the
confidence of an arm recommendation
Bayesian Active Edge Evaluation on Expensive Graphs
Robots operate in environments with varying implicit structure. For instance,
a helicopter flying over terrain encounters a very different arrangement of
obstacles than a robotic arm manipulating objects on a cluttered table top.
State-of-the-art motion planning systems do not exploit this structure, thereby
expending valuable planning effort searching for implausible solutions. We are
interested in planning algorithms that actively infer the underlying structure
of the valid configuration space during planning in order to find solutions
with minimal effort. Consider the problem of evaluating edges on a graph to
quickly discover collision-free paths. Evaluating edges is expensive, both for
robots with complex geometries like robot arms, and for robots with limited
onboard computation like UAVs. Until now, this challenge has been addressed via
laziness i.e. deferring edge evaluation until absolutely necessary, with the
hope that edges turn out to be valid. However, all edges are not alike in value
- some have a lot of potentially good paths flowing through them, and some
others encode the likelihood of neighbouring edges being valid. This leads to
our key insight - instead of passive laziness, we can actively choose edges
that reduce the uncertainty about the validity of paths. We show that this is
equivalent to the Bayesian active learning paradigm of decision region
determination (DRD). However, the DRD problem is not only combinatorially hard,
but also requires explicit enumeration of all possible worlds. We propose a
novel framework that combines two DRD algorithms, DIRECT and BISECT, to
overcome both issues. We show that our approach outperforms several
state-of-the-art algorithms on a spectrum of planning problems for mobile
robots, manipulators and autonomous helicopters
PerfWeb: How to Violate Web Privacy with Hardware Performance Events
The browser history reveals highly sensitive information about users, such as
financial status, health conditions, or political views. Private browsing modes
and anonymity networks are consequently important tools to preserve the privacy
not only of regular users but in particular of whistleblowers and dissidents.
Yet, in this work we show how a malicious application can infer opened websites
from Google Chrome in Incognito mode and from Tor Browser by exploiting
hardware performance events (HPEs). In particular, we analyze the browsers'
microarchitectural footprint with the help of advanced Machine Learning
techniques: k-th Nearest Neighbors, Decision Trees, Support Vector Machines,
and in contrast to previous literature also Convolutional Neural Networks. We
profile 40 different websites, 30 of the top Alexa sites and 10 whistleblowing
portals, on two machines featuring an Intel and an ARM processor. By monitoring
retired instructions, cache accesses, and bus cycles for at most 5 seconds, we
manage to classify the selected websites with a success rate of up to 86.3%.
The results show that hardware performance events can clearly undermine the
privacy of web users. We therefore propose mitigation strategies that impede
our attacks and still allow legitimate use of HPEs
A model for incorporating a clinically-feasible exercise test in paraplegic annual reviews : a tool for stratified cardiopulmonary stress performance classification and monitoring
To identify and characterize an exercise test for use in routine spinal cord injury clinical review, and (ii) to describe levels of, and factors affecting, cardiopulmonary stress performance during exercise in the chronic paraplegic population in Scotland, UK. Cross-sectional study Queen Elizabeth National Spinal Injuries Unit (Glasgow, Scotland) 48 subjects with chronic paraplegia resulting from spinal cord injury at neurological levels T2-L2 Peak oxygen uptake, peak power output, gas exchange threshold and peak heart rate were determined from an incremental arm-cranking exercise test. Using a general linear model, the effects of gender, high (injury level above T6) versus low paraplegia, time since injury, body mass and age on peak oxygen uptake and peak power output were investigated. All 48 subjects completed the arm-cranking exercise test, which was shown to be practical for fitness screening in paraplegia. Men (n=38) had a peak oxygen uptake of 1.302 +/- 0.326 l.min-1 (mean +/- s.d.) and peak power output of 81.6 +/- 23.2W, which was significantly higher than for women (n=10), at 0.832 +/- 0.277 l.min-1 and 50.1 +/- 27.8 W, respectively. There was large intersubject variability in cardiopulmonary performance during arm-cranking exercise testing, but the overall mean for the Scottish population was lower than reference values from other countries. Arm-cranking exercise tests are feasible in the clinical environment. The motivation for their implementation is threefold: (i) to determine cardiopulmonary stress performance of individual paraplegic patients, (ii) to stratify patients into cardiovascular risk categories, and (iii) to monitor the effects of targeted exercise prescription
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