Do Mirrors for Gravitational Waves Exist?

Thin superconducting films are predicted to be highly reflective mirrors for gravitational waves at microwave frequencies. The quantum mechanical non-localizability of the negatively charged Cooper pairs, which is protected from the localizing effect of decoherence by an energy gap, causes the pairs to undergo non-picturable, non-geodesic motion in the presence of a gravitational wave. This non-geodesic motion, which is accelerated motion through space, leads to the existence of mass and charge supercurrents inside the superconducting film. On the other hand, the decoherence-induced localizability of the positively charged ions in the lattice causes them to undergo picturable, geodesic motion as they are carried along with space in the presence of the same gravitational wave. The resulting separation of charges leads to a virtual plasma excitation within the film that enormously enhances its interaction with the wave, relative to that of a neutral superfluid or any normal matter. The existence of strong mass supercurrents within a superconducting film in the presence of a gravitational wave, dubbed the "Heisenberg-Coulomb effect," implies the specular reflection of a gravitational microwave from a film whose thickness is much less than the London penetration depth of the material, in close analogy with the electromagnetic case. The argument is developed by allowing classical gravitational fields, which obey Maxwell-like equations, to interact with quantum matter, which is described using the BCS and Ginzburg-Landau theories of superconductivity, as well as a collisionless plasma model. Several possible experimental tests of these ideas, including mesoscopic ones, are presented alongside comments on the broader theoretical implications of the central hypothesis.Comment: 59 pages, 2 figure

Capturing the essence of folding and functions of biomolecules using Coarse-Grained Models

The distances over which biological molecules and their complexes can function range from a few nanometres, in the case of folded structures, to millimetres, for example during chromosome organization. Describing phenomena that cover such diverse length, and also time scales, requires models that capture the underlying physics for the particular length scale of interest. Theoretical ideas, in particular, concepts from polymer physics, have guided the development of coarse-grained models to study folding of DNA, RNA, and proteins. More recently, such models and their variants have been applied to the functions of biological nanomachines. Simulations using coarse-grained models are now poised to address a wide range of problems in biology.Comment: 37 pages, 8 figure

Sex determination

Multicellular animals are a diverse lot, with widely varied body plans and lifestyles. One feature they share, however, is a nearly universal reliance on sexual reproduction for species propagation. Humans have long been fascinated by human sex differences and formal theories on how human sex is determined date at least to Aristotle (in De Generatione Animalium, ca. 335 BCE). However, it is only in the past couple of decades that the genetic and molecular programs responsible for generating the two sexes have been understood in any detail. Sex, it turns out, can be established by many very different and fast-evolving mechanisms, but often these involve a conserved class of transcriptional regulators, the DM domain proteins

Brownian dynamics of elongated particles in a quasi-2D isotropic liquid

We demonstrate experimentally that the long-range hydrodynamic interactions in an incompressible quasi 2D isotropic fluid result in an anisotropic viscous drag acting on elongated particles. The anisotropy of the drag is increasing with increasing ratio of the particle length to the hydrodynamic scale given by the Saffman-Delbr\"uck length. The micro-rheology data for translational and rotational drags collected over three orders of magnitude of the effective particle length demonstrate the validity of the current theoretical approaches to the hydrodynamics in restricted geometry. The results also demonstrate crossovers between the hydrodynamical regimes determined by the characteristic length scales