The Evening Light

https://scholarexchange.furman.edu/ninety-six-press/1017/thumbnail.jp

The De-Ubiquitinylating Enzyme, USP2, Is Associated with the Circadian Clockwork and Regulates Its Sensitivity to Light

We have identified a novel component of the circadian clock that regulates its sensitivity to light at the evening light to dark transition. USP2 (Ubiquitin Specific Protease 2), which de-ubiquitinylates and stabilizes target proteins, is rhythmically expressed in multiple tissues including the SCN. We have developed a knockout model of USP2 and found that exposure to low irradiance light at ZT12 increases phase delays of USP2−/− mice compared to wildtype. We additionally show that USP2b is in a complex with several clock components and regulates the stability and turnover of BMAL1, which in turn alters the expression of several CLOCK/BMAL1 controlled genes. Rhythmic expression of USP2 in the SCN and other tissues offers a new level of control of the clock machinery through de-ubiqutinylation and suggests a role for USP2 during circadian adaptation to environmental day length changes

(Un)Dressing Decadence: Masquerade and Murder in Mascara

It opens on a blue vista of sea. A white villa looks out over the waves and glows in the evening light. A woman comes out, encased in a tight-fitting white trouser suit. She climbs into a car and drives off. The sea remains, its waves stretching out to the horizon as in a painting by René Magritte. Night falls. We see the woman driving in close-up, her face lit pale yellow by passing cars. We may recognize her as Charlotte Rampling, the cinema’s perverse glamour icon par excellence. Yet her image here is altered, her hair cropped short so she resembles an androgynous boy. Her throat rises from the up-curving collar of her white suit, which encases her like the sculpted calyx of a lily. One earring dangles from one ear. Its white geometrical swirls suggest a sculpture by Constantin Brâncuşi

La Cascade Restaurant at the Sheen Falls Lodge Hotel Dinner Menu, Winter, 2012

“La Cascade Restaurant is one of the best restaurants in Kerry, Ireland boasting an elegant, classical dining room at Sheen Falls Lodge Hotel Kenmare with two Rosettes from the AA for its distinctive style and creative menus. With panoramic windows overlooking the Sheen Waterfalls and onto the bay, the sun\u27s rays flood into the room as guests settle down to breakfast and plan their day. Then, as the evening light changes and dusk approaches, the gentle glow of candlelight and the sounds of the grand piano all beckon guests to dinner. The seasonal menu reflects innovative and creative dishes carefully prepared by Executive Chef Heiko Reibandt and his kitchen brigade. There is an abundance of local produce such as fresh seafood daily from Castletownbere, small cheese-makers such as Milleen\u27s and organic vegetables from local suppliers all creating dishes full of flavour and aroma. “ Taken from La Cascade websitehttps://arrow.tudublin.ie/menus21c/1032/thumbnail.jp

Faculty concert: William Sharp, baritone, Robert Merfeld, piano, Peter Zazofsky, violin, Michael Reynolds, cello

This is the concert program of the Faculty Concert: William Sharp, baritone, Robert Merfeld, piano, Peter Zazofsky, violin, Michael Reynolds, cello performance on Thursday, March 23, 2000 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue. Works performed were Hier in meines Vaters Statte by Johann Sebastian Bach, Sturze zu Boden by J. S. Bach, Nichts ist es spat und fruhe by J. S. Bach, Under the Resurrection Palm by David Liptak, Six Songs for voice, violin, and piano, Op. 54 by Louis Spohr, and La Bonne Chanson, Op. 62 by Gabriel Faure. Digitization for Boston University Concert Programs was supported by the Boston University Humanities Library Endowed Fund

Spartan Daily, October 5, 1934

Volume 23, Issue 11https://scholarworks.sjsu.edu/spartandaily/2190/thumbnail.jp

Turkdean Roman Villa, Gloucestershire: archaeological investigations 1997-1998

Before the transmission of the first ‘live’ Time Team television programme on 23 August 1997, the existence of a Roman villa near Chalkhill Barn in the parish of Turkdean, 12 miles north-east of Cirencester and 2 miles from the Fosse Way, was hardly known to the archaeological community (FIG. 1). That a Roman building did exist in this location had, however, been suspected for a number of years by the landowner, the late Mr Wilf Mustoe. Distinctive linear parchmarks suggestive of buildings had been clearly visible at ground level in the grass pasture each dry summer, and in 1976 Mr Mustoe made a measured sketch plan of them on the back of an envelope. Subsequently the sketch was drawn up into a scale plan entitled ‘Roman villa’ by Simon Goddard, a relation. There was little knowledge of the site outside of Mr Mustoe's family until it was independently ‘discovered’ by local archaeologist Roger Box in August 1996 whilst fortuitously flying over the site in a helicopter. In the evening light Mr Box instantly recognised the parchmarks of an unmistakable Roman villa and took a series of photographs (FIG. 2). Mr Box showed his photographs to Mr Mustoe, and with his agreement wrote to Time Team suggesting that this would be an excellent site for a television programme. Arrangements were duly set in place and the evidence of the cropmarks was confirmed by a trial geophysical survey in March 199