69,297 research outputs found
Exact generator and its high order expansions in the time-convolutionless generalized master equation: Applications to the spin-boson model and exictation energy transfer
The time-convolutionless (TCL) quantum master equation provides a powerful
tool to simulate reduced dynamics of a quantum system coupled to a bath. The
key quantity in the TCL master equation is the so-called kernel or generator,
which describes effects of the bath degrees of freedom. Since the exact TCL
generators are usually hard to calculate analytically, most applications of the
TCL generalized master equation have relied on approximate generators using
second and fourth order perturbative expansions. By using the hierarchical
equation of motion (HEOM) and extended HEOM methods, we present a new approach
to calculate the exact TCL generator and its high order perturbative
expansions. The new approach is applied to the spin-boson model with different
sets of parameters, to investigate the convergence of the high order expansions
of the TCL generator. We also discuss circumstances where the exact TCL
generator becomes singular for the spin-boson model, and a model of excitation
energy transfer in the Fenna-Matthews-Olson complex
Exciting Changes are Coming to The Christian Librarian
Back in 1996 I came on board the TCL team with a dream. My hope was to make TCL a peer reviewed publication. Now, many years later, I am excited to say this dream will soon become a reality! Beginning in 2009, TCL will carry peer reviewed content
Flow cytometric characterization and clinical outcome of CD4+ T-cell lymphoma in dogs: 67 cases.
BackgroundCanine T-cell lymphoma (TCL) is conventionally considered an aggressive disease, but some forms are histologically and clinically indolent. CD4 TCL is reported to be the most common subtype of TCL. We assessed flow cytometric characteristics, histologic features when available, and clinical outcomes of CD4+ TCL to determine if flow cytometry can be used to subclassify this group of lymphomas.ObjectiveTo test the hypothesis that canine CD4+ T-cell lymphoma (TCL) is a homogeneous group of lymphomas with an aggressive clinical course.AnimalsSixty-seven dogs diagnosed with CD4+ TCL by flow cytometry and treated at 1 of 3 oncology referral clinics.MethodsRetrospective multivariable analysis of outcome in canine CD4+ TCL including patient characteristics, treatment, and flow cytometric features.ResultsThe majority of CD4+ TCL were CD45+, expressed low class II MHC, and exhibited an aggressive clinical course independent of treatment regimen (median survival, 159 days). Histologically, CD4+ TCL were classified as lymphoblastic or peripheral T cell. Size of the neoplastic lymphocytes had a modest effect on both PFI and survival in this group. A small number of CD4+ TCL were CD45- and class II MHC high, and exhibited an apparently more indolent clinical course (median survival not yet reached).Conclusions and clinical importanceAlthough the majority of CD4+ TCL in dogs had uniform clinical and flow cytometric features and an aggressive clinical course, a subset had a unique immunophenotype that predicts significantly longer survival. This finding strengthens the utility of flow cytometry to aid in the stratification of canine lymphoma
Magnetism and effect of anisotropy with one dimensional monatomic chain of cobalt by a Monte Carlo simulation
The magnetic properties of the one dimensional (1D) monatomic chain of Co
reported in a previous experimental work are investigated by a classical Monte
Carlo simulation based on the anisotropic Heisenberg model. In our simulation,
the effect of the on-site uniaxial anisotropy, Ku, on each individual Co atom
and the nearest neighbour exchange interaction, J, are accounted for. The
normalized coercivity HC(T)/HC(TCL) is found to show a universal behaviour,
HC(T)/HC(TCL) = h0(e^{TB/T}-e) in the temperature interval, TCL < T < TBCal,
arising from the thermal activation effect. In the above expression, h0 is a
constant, TBCal is the blocking temperature determined by the calculation, and
TCL is the temperature above which the classical Monte Carlo simulation gives a
good description on the investigated system. The present simulation has
reproduced the experimental features, including the temperature dependent
coercivity, HC(T), and the angular dependence of the remanent magnetization,
MR(phi,theta), upon the relative orientation (phi,theta) of the applied field
H. In addition, the calculation reveals that the ferromagnetic-like open
hysteresis loop is a result of a slow dynamical process at T < TBCal. The
dependence of the dynamical TBCal on the field sweeping rate R, the on-site
anisotropy constant Ku, and the number of atoms in the atomic chain, N, has
been investigated in detail.Comment: 20 pages, 7 figures included, J Phys Condens Matter, In Pres
Editorial
The first TCL issue of the new year is now under my belt. As the new Design Editor, the January 2000 TCL was a labor of love. It was also one of trial and error. I learned how to logically arrange the pages and articles within the issue. I experimented with various graphical changes but tried to keep a recognizable style in the grand TLC tradition
Time-Contrastive Learning Based Deep Bottleneck Features for Text-Dependent Speaker Verification
There are a number of studies about extraction of bottleneck (BN) features
from deep neural networks (DNNs)trained to discriminate speakers, pass-phrases
and triphone states for improving the performance of text-dependent speaker
verification (TD-SV). However, a moderate success has been achieved. A recent
study [1] presented a time contrastive learning (TCL) concept to explore the
non-stationarity of brain signals for classification of brain states. Speech
signals have similar non-stationarity property, and TCL further has the
advantage of having no need for labeled data. We therefore present a TCL based
BN feature extraction method. The method uniformly partitions each speech
utterance in a training dataset into a predefined number of multi-frame
segments. Each segment in an utterance corresponds to one class, and class
labels are shared across utterances. DNNs are then trained to discriminate all
speech frames among the classes to exploit the temporal structure of speech. In
addition, we propose a segment-based unsupervised clustering algorithm to
re-assign class labels to the segments. TD-SV experiments were conducted on the
RedDots challenge database. The TCL-DNNs were trained using speech data of
fixed pass-phrases that were excluded from the TD-SV evaluation set, so the
learned features can be considered phrase-independent. We compare the
performance of the proposed TCL bottleneck (BN) feature with those of
short-time cepstral features and BN features extracted from DNNs discriminating
speakers, pass-phrases, speaker+pass-phrase, as well as monophones whose labels
and boundaries are generated by three different automatic speech recognition
(ASR) systems. Experimental results show that the proposed TCL-BN outperforms
cepstral features and speaker+pass-phrase discriminant BN features, and its
performance is on par with those of ASR derived BN features. Moreover,....Comment: Copyright (c) 2019 IEEE. Personal use of this material is permitted.
Permission from IEEE must be obtained for all other uses, in any current or
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or promotional purposes, creating new collective works, for resale or
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this work in other work
Tensor Contraction Layers for Parsimonious Deep Nets
Tensors offer a natural representation for many kinds of data frequently
encountered in machine learning. Images, for example, are naturally represented
as third order tensors, where the modes correspond to height, width, and
channels. Tensor methods are noted for their ability to discover
multi-dimensional dependencies, and tensor decompositions in particular, have
been used to produce compact low-rank approximations of data. In this paper, we
explore the use of tensor contractions as neural network layers and investigate
several ways to apply them to activation tensors. Specifically, we propose the
Tensor Contraction Layer (TCL), the first attempt to incorporate tensor
contractions as end-to-end trainable neural network layers. Applied to existing
networks, TCLs reduce the dimensionality of the activation tensors and thus the
number of model parameters. We evaluate the TCL on the task of image
recognition, augmenting two popular networks (AlexNet, VGG). The resulting
models are trainable end-to-end. Applying the TCL to the task of image
recognition, using the CIFAR100 and ImageNet datasets, we evaluate the effect
of parameter reduction via tensor contraction on performance. We demonstrate
significant model compression without significant impact on the accuracy and,
in some cases, improved performance
A novel representation of energy and signal transformation in measurement systems
This work presents a novel representation of energy and signal transformation in a measurement system, which is essentially a transducer conversion logic or language (TCL). Using two-port and three-port transducers as basic building blocks, it can be utilized to model any measurement system. It has the key features of object-orientation and consists of only text with very simple syntax. The TCL can be easily handled and processed by computers. This paper has demonstrated its use in description, classification, and computer-aided analysis and design of measuring instruments with some preliminary test results. It will find wide applications in modeling, analysis, design, and education in measurement, control, and information processing
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