123,349 research outputs found
Tunable photon blockade in a hybrid system consisting of an optomechanical device coupled to a two-level system
We study photon blockade and anti-bunching in the cavity of an optomechanical
system in which the mechanical resonator is coupled to a two-level system
(TLS). In particular, we analyze the effects of the coupling strength (to the
mechanical mode), transition frequency, and decay rate of TLS on the photon
blockade. The statistical properties of the cavity field are affected by the
TLS, because the TLS changes the energy-level structure of the optomechanical
system via dressed states formed by the TLS and the mechanical resonator. We
find that the photon blockade and tunneling can be significantly changed by the
transition frequency of the TLS and the coupling strength between the TLS and
the mechanical resonator. Therefore, our study provides a method to tune the
photon blockade and tunneling using a controllable TLS.Comment: 11 page
Translesion synthesis in mammalian cells
DNA damage blocks the progression of the replication fork. In order to circumvent the damaged bases, cells employ specialized low stringency DNA polymerases, which are able to carry out translesion synthesis (TLS) past different types of damage. The five polymerases used in TLS in human cells have different substrate specificities, enabling them to deal with many different types of damaged bases. PCNA plays a central role in recruiting the TLS polymerases and effecting the polymerase switch from replicative to TLS polymerase. When the fork is blocked PCNA gets ubiquitinated. This increases its affinity for the TLS polymerases, which all have novel ubiquitin-binding motifs, thereby facilitating their engagement at the stalled fork to effect TLS
What is moving in silica at 1 K? A computer study of the low-temperature anomalies
Though the existence of two-level systems (TLS) is widely accepted to explain
low temperature anomalies in many physical observables, knowledge about their
properties is very rare. For silica which is one of the prototype glass-forming
systems we elucidate the properties of the TLS via computer simulations by
applying a systematic search algorithm. We get specific information in the
configuration space, i.e. about relevant energy scales, the absolute number of
TLS and electric dipole moments. Furthermore important insight about the
real-space realization of the TLS can be obtained. Comparison with experimental
observations is included
Analysis of high quality superconducting resonators: consequences for TLS properties in amorphous oxides
noise caused by microscopic Two-Level Systems (TLS) is known to be very
detrimental to the performance of superconducting quantum devices but the
nature of these TLS is still poorly understood. Recent experiments with
superconducting resonators indicates that interaction between TLS in the oxide
at the film-substrate interface is not negligible. Here we present data on the
loss and frequency noise from two different Nb resonators with and
without Pt capping and discuss what conclusions can be drawn regarding the
properties of TLS in amorphous oxides. We also estimate the concentration and
dipole moment of the TLS.Comment: 8 pages, 5 figure
The dissipative two-level system under strong ac-driving: a combination of Floquet and Van Vleck perturbation theory
We study the dissipative dynamics of a two-level system (TLS) exposed to
strong ac driving. By combing Floquet theory with Van Vleck perturbation theory
in the TLS tunneling matrix element, we diagonalize the time-dependent
Hamiltonian and provide corrections to the renormalized Rabi frequency of the
TLS, which are valid for both a biased and unbiased TLS and go beyond the known
high-frequency and rotating-wave results. In order to mimic environmental
influences on the TLS, we couple the system weakly to a thermal bath and solve
analytically the corresponding Floquet-Bloch-Redfield master equation. We give
a closed expression for the relaxation and dephasing rates of the TLS and
discuss their behavior under variation of the driving amplitude. Further, we
examine the robustness of coherent destruction of tunneling (CDT) and
driving-induced tunneling oscillations (DITO). We show that also for a moderate
driving frequency an almost complete suppression of tunneling can be achieved
for short times and demonstrate the sensitiveness of DITO to a change of the
external parameters.Comment: 21 pages, 18 figures; published versio
Sparsity-Cognizant Total Least-Squares for Perturbed Compressive Sampling
Solving linear regression problems based on the total least-squares (TLS)
criterion has well-documented merits in various applications, where
perturbations appear both in the data vector as well as in the regression
matrix. However, existing TLS approaches do not account for sparsity possibly
present in the unknown vector of regression coefficients. On the other hand,
sparsity is the key attribute exploited by modern compressive sampling and
variable selection approaches to linear regression, which include noise in the
data, but do not account for perturbations in the regression matrix. The
present paper fills this gap by formulating and solving TLS optimization
problems under sparsity constraints. Near-optimum and reduced-complexity
suboptimum sparse (S-) TLS algorithms are developed to address the perturbed
compressive sampling (and the related dictionary learning) challenge, when
there is a mismatch between the true and adopted bases over which the unknown
vector is sparse. The novel S-TLS schemes also allow for perturbations in the
regression matrix of the least-absolute selection and shrinkage selection
operator (Lasso), and endow TLS approaches with ability to cope with sparse,
under-determined "errors-in-variables" models. Interesting generalizations can
further exploit prior knowledge on the perturbations to obtain novel weighted
and structured S-TLS solvers. Analysis and simulations demonstrate the
practical impact of S-TLS in calibrating the mismatch effects of contemporary
grid-based approaches to cognitive radio sensing, and robust
direction-of-arrival estimation using antenna arrays.Comment: 30 pages, 10 figures, submitted to IEEE Transactions on Signal
Processin
Evidence for hydrogen two-level systems in atomic layer deposition oxides
Two-level system (TLS) defects in dielectrics are known to limit the
performance of electronic devices. We study TLS using millikelvin microwave
loss measurements of three atomic layer deposited (ALD) oxide
films--crystalline BeO (), amorphous
(), and amorphous ()--and
interpret them with room temperature characterization measurements. We find
that the bulk loss tangent in the crystalline film is 6 times higher than in
the amorphous films. In addition, its power saturation agrees with an amorphous
distribution of TLS. Through a comparison of loss tangent data to secondary ion
mass spectrometry (SIMS) impurity analysis we find that the dominant loss in
all film types is consistent with hydrogen-based TLS. In the amorphous films
excess hydrogen is found at the ambient-exposed surface, and we extract the
associated hydrogen-based surface loss tangent. Data from films with a factor
of 40 difference in carbon impurities revealed that carbon is currently a
negligible contributor to TLS loss.Comment: 11 pages, 4 figures (preprint format
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