1,961,340 research outputs found
Pulsed Laser Interactions with Space Debris: Target Shape Effects
Among the approaches to the proposed mitigation and remediation of the space
debris problem is the de-orbiting of objects in low Earth orbit through
irradiation by ground-based high-intensity pulsed lasers. Laser ablation of a
thin surface layer causes target recoil, resulting in the depletion of orbital
angular momentum and accelerated atmospheric re-entry. However, both the
magnitude and direction of the recoil are shape dependent, a feature of the
laser-based remediation concept that has received little attention. Since the
development of a predictive capability is desirable, we have investigated the
dynamical response to ablation of objects comprising a variety of shapes. We
derive and demonstrate a simple analytical technique for calculating the
ablation-driven transfer of linear momentum, emphasizing cases for which the
recoil is not exclusively parallel to the incident beam. For the purposes of
comparison and contrast, we examine one case of momentum transfer in the
low-intensity regime, where photon pressure is the dominant momentum transfer
mechanism, showing that shape and orientation effects influence the target
response in a similar, but not identical, manner. We address the related
problem of target spin and, by way of a few simple examples, show how ablation
can alter the spin state of a target, which often has a pronounced effect on
the recoil dynamics.Comment: 51 pages, 14 figures, to appear in Advances in Space Researc
Solving multi-target haptic problems in menu interaction
While haptic feedback has been shown to enhance user performance and satisfaction in single target interactions in desktop user interfaces, it is not clear whether this will hold for more realistic, multi-target interactions. Here we present an experimental study of haptically enhanced menus. We evaluate a visual condition, a haptic condition and an adjusted haptic condition designed to support menu interactions. We conclude that thoughtful design can create multi-target haptic augmentations that provide performance benefits
Acceleration by Strong Interactions
Beyond the attractive strong potential needed for hadronic bound states,
strong interactions are predicted to provide repulsive forces depending on the
color charges involved. The repulsive interactions could in principle serve for
particle acceleration with highest gradients in the order of GeV/fm. Indirect
evidence for repulsive interactions have been reported in the context of heavy
meson production at colliders. In this contribution, we sketch a thought
experiment to directly investigate repulsive strong interactions. For this we
prepare two quarks using two simultaneous deep inelastic scattering processes
off an iron target. We discuss the principle setup of the experiment and
estimate the number of electrons on target required to observe a repulsive
effect between the quarks.Comment: 6 pages, 7 figure
Protein Functional Families to characterise drug-target interactions.
The quest for “magic bullets” has been the driving force in drug discovery during the last two decades. However, the increasing rate of drug failure over this period has occurred concurrently with the assumption that a drug is a selective ligand for a single target. It now seems likely that polypharmacology is the rule rather than the exception [1].
Our previous research shows that protein domains are a good proxy for drug targets, and that drug polypharmacology emerges as a consequence of the multi-domain composition of proteins [2]. In this study, we investigate further the idea that the domain is the druggable entity within a protein target. We have identified a specific class of domains (CATH Functional Families) as the best currently available for identifying drug-target interactions. We show how this opens a new direction in target identification with potential application in drug repurposing.1. Hopkins, AL. (2008) Network pharmacology: the next paradigm in drug discovery. Nat Chem Biol; 4: 682
2. Moya-García AA & Ranea JAG (2013) Insights into polypharmacology from drug-domain associations. Bioinformatics 29: 1934–1937)Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. Universidad de Granad
Final-state interactions in deep-inelastic scattering from a tensor polarized deuteron target
Deep-inelastic scattering (DIS) from a tensor polarized deuteron is sensitive
to possible non-nucleonic components of the deuteron wave function. To
accurately estimate the size of the nucleonic contribution, final-state
interactions (FSIs) need to be accounted for in calculations. We outline a
model that, based on the diffractive nature of the effective hadron-nucleon
interaction, uses the generalized eikonal approximation to model the FSIs in
the resonance region, taking into account the proton-neutron component of the
deuteron. The calculation uses a factorized model with a basis of three
resonances with mass GeV as the relevant set of effective hadron states
entering the final-state interaction amplitude for inclusive DIS. We present
results for the tensor asymmetry observable for kinematics accessible
in experiments at Jefferson Lab and Hermes. For inclusive DIS, sizeable effects
are found when including FSIs for Bjorken , but the overall size of
remains small. For tagged spectator DIS, FSIs effects are largest at
spectator momenta around 300 MeV and for forward spectator angles.Comment: 7 pages, 3 figures, proceedings of the Tensor Polarized Solid Target
Workshop March 10-12, 2014 (Jefferson Lab, Newport News, USA
Structure Functions are not Parton Probabilities
The common view that structure functions measured in deep inelastic lepton
scattering are determined by the probability of finding quarks and gluons in
the target is not correct in gauge theory. We show that gluon exchange between
the fast, outgoing partons and target spectators, which is usually assumed to
be an irrelevant gauge artifact, affects the leading twist structure functions
in a profound way. This observation removes the apparent contradiction between
the projectile (eikonal) and target (parton model) views of diffractive and
small x_{Bjorken} phenomena. The diffractive scattering of the fast outgoing
quarks on spectators in the target causes shadowing in the DIS cross section.
Thus the depletion of the nuclear structure functions is not intrinsic to the
wave function of the nucleus, but is a coherent effect arising from the
destructive interference of diffractive channels induced by final state
interactions. This is consistent with the Glauber-Gribov interpretation of
shadowing as a rescattering effect.Comment: 35 pages, 8 figures. Discussion of physical consequences of final
state interactions amplified. Material on light-cone gauge choices adde
Charged Particle Production in Proton-, Deuteron-, Oxygen- and Sulphur-Nucleus Collisions at 200 GeV per Nucleon
The transverse momentum and rapidity distributions of net protons and
negatively charged hadrons have been measured for minimum bias proton-nucleus
and deuteron-gold interactions, as well as central oxygen-gold and
sulphur-nucleus collisions at 200 GeV per nucleon. The rapidity density of net
protons at midrapidity in central nucleus-nucleus collisions increases both
with target mass for sulphur projectiles and with the projectile mass for a
gold target. The shape of the rapidity distributions of net protons forward of
midrapidity for d+Au and central S+Au collisions is similar. The average
rapidity loss is larger than 2 units of rapidity for reactions with the gold
target. The transverse momentum spectra of net protons for all reactions can be
described by a thermal distribution with `temperatures' between 145 +- 11 MeV
(p+S interactions) and 244 +- 43 MeV (central S+Au collisions). The
multiplicity of negatively charged hadrons increases with the mass of the
colliding system. The shape of the transverse momentum spectra of negatively
charged hadrons changes from minimum bias p+p and p+S interactions to p+Au and
central nucleus-nucleus collisions. The mean transverse momentum is almost
constant in the vicinity of midrapidity and shows little variation with the
target and projectile masses. The average number of produced negatively charged
hadrons per participant baryon increases slightly from p+p, p+A to central
S+S,Ag collisions.Comment: 47 pages, submitted to Z. Phys.
Complementarity of dark matter detectors in light of the neutrino background
Direct detection dark matter experiments looking for WIMP-nucleus elastic
scattering will soon be sensitive to an irreducible background from neutrinos
which will drastically affect their discovery potential. Here we explore how
the neutrino background will affect future ton-scale experiments considering
both spin-dependent and spin-independent interactions. We show that combining
data from experiments using different targets can improve the dark matter
discovery potential due to target complementarity. We find that in the context
of spin-dependent interactions, combining results from several targets can
greatly enhance the subtraction of the neutrino background for WIMP masses
below 10 GeV/c and therefore probe dark matter models to lower
cross-sections. In the context of target complementarity, we also explore how
one can tune the relative exposures of different target materials to optimize
the WIMP discovery potential.Comment: 13 pages, 12 figures, 3 table
Bilinear Graph Neural Network with Neighbor Interactions
Graph Neural Network (GNN) is a powerful model to learn representations and
make predictions on graph data. Existing efforts on GNN have largely defined
the graph convolution as a weighted sum of the features of the connected nodes
to form the representation of the target node. Nevertheless, the operation of
weighted sum assumes the neighbor nodes are independent of each other, and
ignores the possible interactions between them. When such interactions exist,
such as the co-occurrence of two neighbor nodes is a strong signal of the
target node's characteristics, existing GNN models may fail to capture the
signal. In this work, we argue the importance of modeling the interactions
between neighbor nodes in GNN. We propose a new graph convolution operator,
which augments the weighted sum with pairwise interactions of the
representations of neighbor nodes. We term this framework as Bilinear Graph
Neural Network (BGNN), which improves GNN representation ability with bilinear
interactions between neighbor nodes. In particular, we specify two BGNN models
named BGCN and BGAT, based on the well-known GCN and GAT, respectively.
Empirical results on three public benchmarks of semi-supervised node
classification verify the effectiveness of BGNN -- BGCN (BGAT) outperforms GCN
(GAT) by 1.6% (1.5%) in classification accuracy.Codes are available at:
https://github.com/zhuhm1996/bgnn.Comment: Accepted by IJCAI 2020. SOLE copyright holder is IJCAI (International
Joint Conferences on Artificial Intelligence), all rights reserve
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