5,339,475 research outputs found
The Amnesiac Consciousness of the Contemporary Holocaust Novel: Lily Brett’s Too Many Men and Jonathan Safran Foer’s Everything Is Illuminated
No abstract (available)
Water for food, water for life: a comprehensive assessment of water management in agriculture: summary. In Arabic
Water management / Irrigation management / Policy / Water scarcity / Poverty / Water rights / Ecosystems / Rainfed farming
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Electrospray synthesis of PLGA TIPS microspheres
We successfully demonstrate the synthesis of polymer microspheres using a single electrospray source, and show their physical characterisation. Electrospray has proven to be a versatile method to manufacture particles, giving tight control over size with quasi-monodisperse size distributions. It is a liquid atomisation technique that generates a monodisperse population of highly charged liquid droplets over a broad size range (nanometres to tens of microns). The droplets contain liquid precursors for the in-flight synthesis of particles, and control over the trajectory of these droplets can be precisely manipulated with the use of electric fields to drive them to a grounded substrate. This study reports a method to synthesize poly(lactic-co-glycolic) acid (PLGA) microspheres using the electrospray and thermally induced phase separation (TIPS) techniques, followed by subsequent freeze-drying, for particle production. These microspheres are of interest as vehicles for controlled drug release systems
Are There Good Mistakes? A Theoretical Analysis of CEGIS
Counterexample-guided inductive synthesis CEGIS is used to synthesize
programs from a candidate space of programs. The technique is guaranteed to
terminate and synthesize the correct program if the space of candidate programs
is finite. But the technique may or may not terminate with the correct program
if the candidate space of programs is infinite. In this paper, we perform a
theoretical analysis of counterexample-guided inductive synthesis technique. We
investigate whether the set of candidate spaces for which the correct program
can be synthesized using CEGIS depends on the counterexamples used in inductive
synthesis, that is, whether there are good mistakes which would increase the
synthesis power. We investigate whether the use of minimal counterexamples
instead of arbitrary counterexamples expands the set of candidate spaces of
programs for which inductive synthesis can successfully synthesize a correct
program. We consider two kinds of counterexamples: minimal counterexamples and
history bounded counterexamples. The history bounded counterexample used in any
iteration of CEGIS is bounded by the examples used in previous iterations of
inductive synthesis. We examine the relative change in power of inductive
synthesis in both cases. We show that the synthesis technique using minimal
counterexamples MinCEGIS has the same synthesis power as CEGIS but the
synthesis technique using history bounded counterexamples HCEGIS has different
power than that of CEGIS, but none dominates the other.Comment: In Proceedings SYNT 2014, arXiv:1407.493
Human-Centric Program Synthesis
Program synthesis techniques offer significant new capabilities in searching for programs that satisfy high-level specifications. While synthesis has been thoroughly explored for input/output pair specifications (programming-by-example), this paper asks: what does program synthesis look like beyond examples? What actual issues in day-to-day development would stand to benefit the most from synthesis? How can a human-centric perspective inform the exploration of alternative specification languages for synthesis? I sketch a human-centric vision for program synthesis where programmers explore and learn languages and APIs aided by a synthesis tool
On the use of observation equivalence in synthesis abstraction
In a previous paper we introduced the notion of synthesis abstraction, which allows efficient compositional synthesis of maximally permissive supervisors for large-scale systems of composed finite-state automata. In the current paper, observation equivalence is studied in relation to synthesis abstraction. It is shown that general observation equivalence is not useful for synthesis abstraction. Instead, we introduce additional conditions strengthening observation equivalence, so that it can be used with the compositional synthesis method. The paper concludes with an example showing the suitability of these relations to achieve substantial state reduction while computing a modular supervisor
The Materials Science Procedural Text Corpus: Annotating Materials Synthesis Procedures with Shallow Semantic Structures
Materials science literature contains millions of materials synthesis
procedures described in unstructured natural language text. Large-scale
analysis of these synthesis procedures would facilitate deeper scientific
understanding of materials synthesis and enable automated synthesis planning.
Such analysis requires extracting structured representations of synthesis
procedures from the raw text as a first step. To facilitate the training and
evaluation of synthesis extraction models, we introduce a dataset of 230
synthesis procedures annotated by domain experts with labeled graphs that
express the semantics of the synthesis sentences. The nodes in this graph are
synthesis operations and their typed arguments, and labeled edges specify
relations between the nodes. We describe this new resource in detail and
highlight some specific challenges to annotating scientific text with shallow
semantic structure. We make the corpus available to the community to promote
further research and development of scientific information extraction systems.Comment: Accepted as a long paper at the Linguistic Annotation Workshop (LAW)
at ACL 201
Reconstitution of recombination-associated DNA synthesis with human proteins.
The repair of DNA breaks by homologous recombination is a high-fidelity process, necessary for the maintenance of genome integrity. Thus, DNA synthesis associated with recombinational repair must be largely error-free. In this report, we show that human DNA polymerase delta (δ) is capable of robust DNA synthesis at RAD51-mediated recombination intermediates dependent on the processivity clamp PCNA. Translesion synthesis polymerase eta (η) also extends these substrates, albeit far less processively. The single-stranded DNA binding protein RPA facilitates recombination-mediated DNA synthesis by increasing the efficiency of primer utilization, preventing polymerase stalling at specific sequence contexts, and overcoming polymerase stalling caused by topological constraint allowing the transition to a migrating D-loop. Our results support a model whereby the high-fidelity replicative DNA polymerase δ performs recombination-associated DNA synthesis, with translesion synthesis polymerases providing a supportive role as in normal replication
Application of Permutation Group Theory in Reversible Logic Synthesis
The paper discusses various applications of permutation group theory in the
synthesis of reversible logic circuits consisting of Toffoli gates with
negative control lines. An asymptotically optimal synthesis algorithm for
circuits consisting of gates from the NCT library is described. An algorithm
for gate complexity reduction, based on equivalent replacements of gates
compositions, is introduced. A new approach for combining a group-theory-based
synthesis algorithm with a Reed-Muller-spectra-based synthesis algorithm is
described. Experimental results are presented to show that the proposed
synthesis techniques allow a reduction in input lines count, gate complexity or
quantum cost of reversible circuits for various benchmark functions.Comment: In English, 15 pages, 2 figures, 7 tables. Proceeding of the RC 2016
conferenc
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