2,092 research outputs found

    Exploring missing heritability in neurodevelopmental disorders:Learning from regulatory elements

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    In this thesis, I aimed to solve part of the missing heritability in neurodevelopmental disorders, using computational approaches. Next to the investigations of a novel epilepsy syndrome and investigations aiming to elucidate the regulation of the gene involved, I investigated and prioritized genomic sequences that have implications in gene regulation during the developmental stages of human brain, with the goal to create an atlas of high confidence non-coding regulatory elements that future studies can assess for genetic variants in genetically unexplained individuals suffering from neurodevelopmental disorders that are of suspected genetic origin

    Transformative learning relationships and the adult educator’s countertransference: a Jungian arts-based duoethnography

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    Transformative learning theory developed from Jack Mezirow’s seminal work on perspective transformation, is a predominant paradigm within adult education scholarship. Recent developments include Jungian perspectives in transformative learning that challenge the dominance of Mezirow’s rational conceptualisation and the exclusion of non-rational and unconscious aspects of learning. Whilst Jungian contributors elevate the role of the unconscious in transformative learning theory, scant attention is paid to the unconscious dynamics between educator and adult learner set within an intersubjective matrix. What is absent is any mention that feelings stirred up in the process of transformative learning might belong within a reciprocal relationship. Jung, who is arguably the pioneer of countertransference, offers a definite point of view about the importance of the subjective responses of the analyst and his/her ability to be influenced and impacted by the client. If the analyst is to transform others, then the analyst needs to be transformed. This relationship of mutual transformation is reconceptualised as a transformative learning relationship. A transformative learning relationship provides an intersubjective frame for exploring countertransferences and the emotional experience of the adult educator. The devised research method of collaborative imaginative engagement is an innovative post-Jungian extension of Jung’s method of active imagination, that involves two adult educators making and working with images of countertransference. The findings are presented as an arts-based duoethnographic portrayal of a co- individuation process between two adult educators. This duoethnographic process of co-individuation prototypes transformative reciprocity within the educator/learner relationship. This research addresses the imbalance or ‘one sidedness’ within transformative learning theory, that overlooks the educator’s subjective and intersubjective experience in favour of the learner’s experience. In doing so, the research contributes a more holistic and collaborative understanding of transformative learning that shows how both learner and educator can be inextricably bound together through a process of mutual transformation

    Stories from the river: developing political awareness within psychotherapy in counselling sexual violence

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    From the stories in the river (Solnit, 2020) to the process of unfolding within the counselling room; this thesis invites, you, the reader, to join my fictive clients and I on a journey of observing how the ideologies (Kearney, 2018) of a post Trump era have continued to simmer within ourselves as individuals as well as the practice of counselling and psychotherapy when working with those who have experienced sexual violence. From the noticing of the ideologies instilled within our identities, to the re-emergence of the structural inequalities of oppression in the political world around us, the phenomenological contextualism of this process grapples with how the experience of relating between counsellor and client initiates the unfolding of such ideologies. A journey that may bring anxiety as counselling training has continued to ignore the context of these ideologies, leaving trainees with expectations of how this may be separate to the process (Kearney, 2018) rather than an important part of it. The hope, or rather the invitation, is to discover a language for this once ignored area of counselling theory and show you, the reader, how I grapple with the parts of my identity affected by Trumpism within the counselling room as I work within the streams of Islamophobia, Transphobia, and Neoliberal Feminist forced ideologies upon individuals who have experienced sexual violence through the reflective process of intersectional feminism. With fictionalisation and the display of my own reflexivity (Etherington, 2004), this journey from the river, to creation of my fictive clients, to the murky soup it generates, and the tasting that follows, leaves blueprints to how trainees, and you, the reader, may also wonder upon and discover their own language for the articulating these ideologies that appear within the counselling session when working with those who have experienced sexual violence

    Planetary Hinterlands:Extraction, Abandonment and Care

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    This open access book considers the concept of the hinterland as a crucial tool for understanding the global and planetary present as a time defined by the lasting legacies of colonialism, increasing labor precarity under late capitalist regimes, and looming climate disasters. Traditionally seen to serve a (colonial) port or market town, the hinterland here becomes a lens to attend to the times and spaces shaped and experienced across the received categories of the urban, rural, wilderness or nature. In straddling these categories, the concept of the hinterland foregrounds the human and more-than-human lively processes and forms of care that go on even in sites defined by capitalist extraction and political abandonment. Bringing together scholars from the humanities and social sciences, the book rethinks hinterland materialities, affectivities, and ecologies across places and cultural imaginations, Global North and South, urban and rural, and land and water

    Exploring missing heritability in neurodevelopmental disorders:Learning from regulatory elements

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    Reframing museum epistemology for the information age: a discursive design approach to revealing complexity

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    This practice-based research inquiry examines the impact of an epistemic shift, brought about by the dawning of the information age and advances in networked communication technologies, on physical knowledge institutions - focusing on museums. The research charts adapting knowledge schemas used in museum knowledge organisation and discusses the potential for a new knowledge schema, the network, to establish a new epistemology for museums that reflects contemporary hyperlinked and networked knowledge. The research investigates the potential for networked and shared virtual reality spaces to reveal new ‘knowledge monuments’ reflecting the epistemic values of the network society and the space of flows. The central practice for this thesis focuses on two main elements. The first is applying networks and visual complexity to reveal multi-linearity and adapting perspectives in relational knowledge networks. This concept was explored through two discursive design projects, the Museum Collection Engine, which uses data visualisation, cloud data, and image recognition within an immersive projection dome to create a dynamic and searchable museum collection that returns new and interlinking constellations of museum objects and knowledge. The second discursive design project was Shared Pasts: Decoding Complexity, an AR app with a unique ‘anti-personalisation’ recommendation system designed to reveal complex narratives around historic objects and places. The second element is folksonomy and co-design in developing new community-focused archives using the community's language to build the dataset and socially tagged metadata. This was tested by developing two discursive prototypes, Women Reclaiming AI and Sanctuary Stories

    Care for the Land: Restoration as Interspecies Care Labor and Emergent Activism at the Hawaiian Fishpond-scape

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    In the last two decades, environmental NGOs on the islands of Hawai’I have been leading efforts to restore traditional land practices and foodways, among them fishpond, or loko i’a, which are traditional aquaculture infrastructures that ensure a stable production of fish protein. This ethnographic study of loko i’a restoration projects is informed by four months of fieldwork grounded in participant observation at Paepae O He’eia, a non-profit organization on the windward side of O’ahu heading the restorative effort at He’eia fishpond. My thesis addresses the ethics of care, labor, and Indigenous worldmaking emerging from ecological and cultural restoration of fishponds that have been neglected and disrepaired due to colonialism and climate disasters. The project explores fishpond restoration at He’eia to understand their centrality for community building for all beings, for human and other-than human actors, as well as creating more expansive frameworks of Indigenous sovereignty and activism. By investigating the role and contradictions of environmental “care” practices, I illuminate multispecies collaborative survival, resistance, and Indigenous world-making practices in the age of the Anthropocene

    Throwing therapy at the problem mental health and humanitarian intervention in Palabek refugee settlement, northern Uganda

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    This thesis examines the social, moral, and political lives of humanitarian mental health interventions in a refugee settlement in Uganda. It is written at the junction of two increasingly significant trends: the search for durable solutions for mass displacement, and the establishment of the field of global mental health as a key actor in the management of psychological suffering across the Global South. Through a scalar structure, it interrogates the intersections of psychological programmes with socio-economic conditions of chronic poverty and food insecurity, from policy discourses to refugees’ phenomenological experiences of suffering. In so doing, it critically examines the political significance and therapeutic potential of mental health interventions in extremely resource-poor contexts. Global mental health scholars and practitioners have developed approaches to refugee mental health based on three assumptions: that refugees’ emotional distress should be tackled by purely psychological interventions; that these programmes are clinically significant and politically neutral; and that the ‘contextual’ factors that should be considered in their implementation mostly concern ‘local’ interpretations of mental health and illness which diverge from Western biomedical frameworks. By ethnographically exploring experiences of psychological suffering among South Sudanese – and particularly Acholi – refugees in the settlement of Palabek, northern Uganda, this thesis disputes these contentions. Based on fourteen months of in-depth ethnographic fieldwork, this thesis puts forward a critique of global mental health and humanitarian interventions that takes seriously the role of poverty and power in shaping refugees’ afflictions. This thesis shows that forms of suffering experienced by refugees in Uganda are closely linked to the structural constraints of life in displacement. It shows how these interventions intersect with refugees’ phenomenological experiences of temporality and moral personhood. In so doing it argues that, when divorced from direct engagement with forms of structural injustice, current global mental health approaches actively ‘do harm’ by contributing to refugees’ psychological afflictions. Finally, this thesis proposes new directions for refugee and global mental health; it argues for a ‘temporal turn’ in refugee mental health which foregrounds refugees’ moral agency, and for the central role of livelihood interventions in generating therapeutic outcomes
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