Differential genetic advantages in youth and in aging, or how to die healthy

Human society ages at a steady rate, that is, the proportion of adult and elderly individuals increases constantly because of improved living conditions and the advances in medical care. This means that very soon the tradeoff between the advantages in old age conferred by alleles disadvantageous or neutral in young age would begin to show, providing the fascinating opportunity of studying the interplay between genetic factors and environment outside the framework of reproductive capacity and in the unique milieu of the aging cell. Being healthy and/or health-conscious in youth does not guarantee for successful aging or even that the person would live up to the average life expectancy of the population. Therefore, successful aging and longevity are related to a healthy-conscious attitude to a degree only. The present paper reviews the basic genetic and evolutionary mechanisms which have operated during human history so as to ensure survival of humankind and the possible factors preventing or contributing to successful aging

Us, Them, and Me! Intergroup and personal challenges of aging successfully

This Keynote Address was delivered at the 73 rd . Annual New York State Communication Association Conference on October 16, 2015. After an anecdotal foray into how he came to study “geronto-communication”, Dr. Giles reviewed his and others’ research and theory on the interfaces between intergenerational communication, subjective health, and aging across many Western and Asian settings. This programmatic body of work was, in large part, guided by communication accommodation theory (which was briefly overviewed). Thereafter, Dr. Giles introduced various views of successful aging and the role of communication practices therein. This led to the formulation and testing of a new theoretical framework, the communication ecology model of successful aging. The thrust of this work is even more poignant as lifespan boundaries and expectations are being incrementally extended

Tracing the Origins of Successful Aging: The Role of Childhood Conditions and Societal Context

This study investigates the role of childhood conditions and societal context in older Europeans’ propensity to age successfully, controlling for later life risk factors. Successful aging was assessed following Rowe and Kahn’s conceptualization, using baseline interviews from the first two waves of the Survey of Health, Ageing and Retirement in Europe (SHARE). These data were merged with retrospective life-histories of participants from 13 Continental European countries, collected in 2008-09 as part of the SHARELIFE project. Our sample consists of 22,474 men and women, who are representative of the non-institutionalized population aged 50 or older (mean age: 63.3) in their respective country. Estimating multilevel logistic models, we controlled for demographics (age, sex), childhood conditions (SES, health, cognition), later life risk factors (various dimensions of SES and health behaviors), as well as country-level measures of public social expenditures and social inequality. There is an dependent association of childhood living conditions with elders’ odds of aging well. Higher parental SES, better math and reading skills, as well as self-reports of good childhood health were positively associated with successful aging, even if contemporary characteristics were controlled for. Later-life SES and health behaviors exhibited the expected correlations with our dependent variable. Moreover, higher levels of public social expenditures and lower levels of income inequality were associated with a greater probability to meet Rowe and Kahn’s successful aging criterion. We conclude that unfavorable childhood conditions exhibit a harmful influence on individuals’ chances to age well across all European welfare states considered in this study. Policy interventions should thus aim at improving the conditions for successful aging throughout the entire life-course.

Determinants of successful aging: implications from Japan

W obliczu zjawiska wydłużania się średniej długości ludzkiego życia, ważne jest, by naukowo zająć się problematyką jego jakości, ponieważ dłuższemu życiu nie zawsze towarzyszy dobre zdrowie. Ludzie żyją dłużej, ale ich stan zdrowia może się pogarszać. Optymistyczny jest fakt, że ludność Europy Środkowo-Wschodniej, w tym Polacy, żyją coraz dłużej i dłużej pozostają w dobrej kondycji, pojawiają się jednak problemy charakterystyczne dla szybko starzejących się społeczeństw. Z tego punktu widzenia Japonia może służyć jako cenny przykład do zrozumienia wyzwań stojących przed starzejącym się społeczeństwem. Rząd japoński zogniskował swoją uwagę na integracji społecznej (problemie niesprawiedliwego i bolesnego wykluczenia z powodu podeszłego wieku), która okazuje się niezmiernie istotna dla starszych osób. Ponadto w Japonii funkcjonują odpowiednie programy państwowe i prywatne, a także opracowano mechanizmy pozwalające cieszyć się przywilejami wieku poprzez promowanie aktywnego stylu życia. Poza tym obserwuje się rosnące zainteresowanie nowymi technologiami, przede wszystkim robotami, wykorzystywanymi m.in. w dziedzinie opieki nad seniorami. Podsumowując, ponieważ zjawisko starzenia się społeczeństw jest powszechne i ostatecznie będzie dotyczyć każdego kraju na świecie, przypadek Japonii może służyć jako przykład empiryczny dla innych krajów, które wkrótce staną przed podobnymi wyzwaniami. Autorka stwierdza, że wskazane jest podejmowanie większej liczby przedsięwzięć, dzięki którym można szerzyć wiedzę i wymieniać się doświadczeniami i właśnie konferencja „2014 – New Opportunities for Japan and V-4 Cooperation” znakomicie wpisuje się swoimi założeniami w ten nurt.The organizers of the conference wish to acknowledge the National Bank of Poland’s generous funding of this publication

Sleep and inflammation in resilient aging.

Sleep quality is important to health, and increasingly viewed as critical in promoting successful, resilient aging. In this review, the interplay between sleep and mental and physical health is considered with a focus on the role of inflammation as a biological pathway that translates the effects of sleep on risk of depression, pain and chronic disease risk in aging. Given that sleep regulates inflammatory biologic mechanisms with effects on mental and physical health outcomes, the potential of interventions that target sleep to reduce inflammation and promote health in aging is also discussed

Aging in the Social Space

A publication called Aging in the Social Space is a compilation of studies, which deal with theoretical understanding and empirical solutions, learning about problem spheres, specifying content parallels of social, legal, economic, moral and ethical views on senior issues in society, which are closely related to each other and are interconnected. This publication focus on the case study of Poland. It is supposed to provide a multidimensional view of old age issues and issues related to aging and care for old people in society. We believe that it is natural also to name individual spheres, in which society has some eff ect, either direct or indirect, within issues concerning seniors. Learning about these spheres is the primary prerequisite for successful use of social help to seniors in society

Psychological principles of successful aging technologies: A mini-review

Based on resource-oriented conceptions of successful life-span development, we propose three principles for evaluating assistive technology: (a) net resource release; (b) person specificity, and (c) proximal versus distal frames of evaluation. We discuss how these general principles can aid the design and evaluation of assistive technology in adulthood and old age, and propose two technological strategies, one targeting sensorimotor and the other cognitive functioning. The sensorimotor strategy aims at releasing cognitive resources such as attention and working memory by reducing the cognitive demands of sensory or sensorimotor aspects of performance. The cognitive strategy attempts to provide adaptive and individualized cuing structures orienting the individual in time and space by providing prompts that connect properties of the environment to the individual's action goals. We argue that intelligent assistive technology continuously adjusts the balance between `environmental support' and `self-initiated processing' in person-specific and aging-sensitive ways, leading to enhanced allocation of cognitive resources. Furthermore, intelligent assistive technology may foster the generation of formerly latent cognitive resources by activating developmental reserves (plasticity). We conclude that `lifespan technology', if co-constructed by behavioral scientists, engineers, and aging individuals, offers great promise for improving both the transition from middle adulthood to old age and the degree of autonomy in old age in present and future generations. Copyright (C) 2008 S. Karger AG, Basel

Promoting Successful Cognitive Aging: A Comprehensive Review

Promoting successful cognitive aging is a topic of major importance to individuals and the field of public health. This review presents a coherent framework not only for evaluating factors, protective activities, and enhancing agents that have already been proposed, but also ones that will be put forward in the future. The promotion of successful cognitive aging involves the dual goals of preventing loss of information processing capacity and cognitive reserve, and enhancing brain capacity and cognitive reserve. Four major lines of evidence are available for evaluating whether a proposed factor promotes successful cognitive aging: 1) epidemiologic/cohort studies; 2) animal/basic science studies; 3) human "proof-of-concept" studies; and 4) human intervention studies. Each line of evidence has advantages and limitations that will be discussed. Through illustrative examples, we trace the ways in which each method informs us about the potential value of several proposed factors. Currently, lines of converging evidence allow the strongest case to be made for physical and cognitively stimulating activities. Although epidemiological data seem to favor the use of statins to lower the risk of dementia, more definitive recommendations await further randomized controlled studies. There is presently no clear evidence that antioxidants or Ginkgo biloba promote successful cognitive aging. The impact of resveratrol, fish oil, and a long list of other proposed agents needs to be determined. Clinicians remain well-positioned to identify and aggressively treat vascular risk factors, diabetes, sleep disorders, and other conditions that may reduce brain capacity, and to encourage activities that can build cognitive reserve